STI Flashcards
what should be done first speculum or STI check
STI check
how to test for GC/CT in female
Vulvovaginal swab - NAAT
how to test for STI in men
first void urine
what extra test should you perform is symptomatic eg discharge
microscopy
what is a normal vaginal pH
3.5-4.5
what additional step must be done in vaginal microscopy
wet prep
treatment of chlamydia
doxycycline 100mg BD for 1 week
treatment of PID
1G ceftriaxone IM, Doxycycline 100mg BD 2weeks, metronidazole 400mg BD 2 weeks
most common STI
chlamydia
incubation of chlamydia
7-21 days
what serovars of chlamydia are responsible for neonatal conjunctivitis and PID
serovars D-K
what serovars of chlamydia are responsible for
lymphogranuloma venerum
serovars L1-L3
what discharge colour is seen in chlamydia in men
milky
what type of organism is gonorrhoea
gram negative intracellular diplococci
treatment of gonorrhoea
Im ceftriaxone 1G
what STI should test for cure be done in
gonorrhoea
incubation time for gonorrhoea
1-5 days
management of HSV 1
aciclovir
cause of genital blisters
HSV 1
what causes syphilis
treponema pallidum
sphiroceate
syphilis
how is syphilis diagnosed
serology - PCR
treatment of syphilis
benzylypenicillin
condylomata lata
syphilis
macular follicular pustular rsh on palms and soles
syphilis
what test must be done in syphilis until negative
rapid plasma reagent
most common viral STI
HPV
high risk HPV
18, 16
low risk hpv
6,11
what HPVS are vaccinated for
6,11,16,18
what HPV responsible for palmer warts
1/2
cauliflower warts
HPV
treatment of HPV warts
podophyllotoxin
imiquimid
cryotherapy
what type of HIV was responsible for epidemic
group M of HIV -1
what HIV Is seen mostly in Africa
HIV 2
What surface antigens are seen on an HIV cell
GP120, GP 40
what receptor does HIV bind to on a non infected cell
CCR5 co-receptor and CD4 receptor
what enzyme is responsible for replicating viral DNA
reverse transcriptase
how long after HIV exposure is infection established
72 hours
how long after HIV exposure is PEP effective
72 hours
how is HIV disseminated
via lymph
what cells are targeted in HIV
CD4+ cells (T-cells)
what is a normal CD4 count
500-1600
a CD4 count of less than what is bad
200
average time to death from HIV without treatment
9-11
what is the CD4 count seen in Pneumocystic pneumonia -PCP (pneumocystis jiroveci)
<200
what CD4 count is toxoplasmosis seen at
<150
multiple ring enhancing lesions on CT in HIV
toxoplasmosis
CD4 count when infected with CMV
<50
what causes progressive multifocal leukoencephalopathy seen in HIV and what is CD4 count
John Cunningham virus cd4<100
what is HAART - how many drugs, how many classes
HIghyl active anti-retroviral therapy
combo of 3 drug for at least 2 different drug classes
a viral load of what is untransmissable
<200
what drugs make up PrEP
tenofovir and emricitabine
how long is post exposure prophylaxis taken for
4 weeks
what is condylomata acuminata
genital warts caused by HPV
what rashes are seen in secondary syphilis
condylomata lata
maculo rash on palms, soles and trunk
buccal snail trail
examples of non -treponemal tests in syphilis
Rapis plasma reagent
venreal disease researh lab
treatment of syphilis
IM ben pen
things seen in teritary syphilis
argyly robertson pupil
gumma
what is argyl robertson pupil
accomodates but doesnt constrict to light
incubation time of syphilis
9-90 days
symptoms of epidydimo-orchitis
testcular pain and swelling
discharge may be present but often not
causes of epididymo-orchitis
younger adults -chlamydia and gonorrhoea
older - e.coli
investigation of epididymo-orchitis
younger- STI screen
older - MSU and culture + microscopy
causes of non-gonococcal urethritis
chlamydia
ureaplasm ureatylicum
mycoplasma genitalium
order ivestigation in STI chec for urethritis
urethral swabs for gram stain and culture
First void urine for NAAT
revtal swab??
how long after gonorrhoea treatment do you test for cure
do you need to partner notify
2-3 weeks
yes
what colour bottle is used to swab for culture nad microscopy
blue
what complication seconday to PID involving th eliver may occure
heaptic adhesin s- fitz-hugh curtis
