STI Flashcards

1
Q

Painful, irregularly chapped, deep red ulcerations, with red halo.

A

Chancroid

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2
Q

How to Dx Chancroid

A

Culture - definitive dx

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3
Q

What should you test a patient for that has been dx with chancroid

A

Test for HIV at time of dx

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4
Q

First line Tx for chancroid

A

First line - Azithromycin X 1

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5
Q

Disease caused by 3 unique strains of chlamydia trachomatis

A

LGV - Lymphogranuloma venereum

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6
Q

In LGV what s/s would you see during the primary stage

A

small, painless erosions, that heal quickly

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7
Q

In LGV what s/s would you see during the inguinal stage

A

lymphadenopathy, may have HA or fever

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8
Q

In LGV what s/s would you see during the late stage

A

Anorectal swelling, peri-rectal abscess, fistulae, or swelling or ulcerations on labia

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9
Q

How do you confirm dx of LGV

A

Confirm with serological LCG complement fixation test.

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10
Q

When diagnosing LGV if the titer is 1:16 what does that mean

A

suspected LGV

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11
Q

When diagnosing LGV if the titer is >1:64 what does that mean

A

Diagnostic for LGV

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12
Q

First line treatment for LGV

A

Doxycycline 100 mg BID x 21 days

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13
Q

Herpes simplex virus HSV - what are the two types and where are they located

A

HSV 1 - oral “cold sores”

HSV 2 - genital herpes

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14
Q

Multiple, painful, vesicular or ulcerated lesions that last 12 days during an initial breakout and 4-5 days during a reoccurring breakout.

A

S/S HSV

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15
Q

Causes flu-like symptoms, and patient may feel tingling at the site of a lesion before the lesion presents

A

HSV

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16
Q

how to DX HSV

A

NAAT - nucleic acid amplification testing (to detect nucleic acid sequence of organisms)

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17
Q

Tx for HSV

A

Acyclovir

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18
Q

Other name for poxvirus

A

Molluscum contagiosa

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19
Q

Pearly, raised painless, flesh-colored lesions with dimpled centers

A

Mulluscum contagiosum

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20
Q

How to dx Mulluscum contagiosum

A

By visual inspection

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21
Q

How to tx Mulluscum contagiosum

A

No treatment

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22
Q

How long do Mulluscum contagiosum lesions last

A

month to years

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23
Q

Can you be reinfected with Mulluscum contagiosum

A

Once healed; lifetime immunity

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24
Q

If Mulluscum contagiosum lesions become a problem to look at what can be done

A

Cryotherapy - will scar

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25
Q

What are the three stages of syphilis

A

Primary (chancre), Secondary (rash), and Late (gumma lesions)

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26
Q

S/S primary Syphilis

A

Painless ulcer at initial site of contact called a chancre

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27
Q

S/S secondary syphilis

A

Secondary; maculopapular rash on palms of hands and soles of the feet, flu like s/s

28
Q

S/S late syphilis

A

Late stage; cardiac, near, ophthalmic, auditory, and gummatous lesions (gammas)

29
Q

What is a gumma lesion and when would you expect to see a gumma lesion

A

Center necrotic tissue and has a rubbery texture - late stage syphilis

30
Q

If a patient has syphilis what should you also test for

A

HIV

31
Q

How to dx syphilis

A

Dark field microscopy

32
Q

What will be seen on dark field microscopy if a patient has syphilis

A

+ for spirochetes

33
Q

hat are 4 most common STI

A

Chamydia, gonorrhea, syphilis, and trichomonas

34
Q

How are Chamydia, gonorrhea, syphilis, and trichomonas cured

A

abx tx

35
Q

What are the 3 common viral STI

A

HSV, HIV, HPV

36
Q

Tx of primary and secondary syphilis

A

Benzathine PCN G; IM x1

37
Q

Tx of late stage syphilis

A

PCN B IM weekly for 3 doses

38
Q

What STI gives women these symptoms Frothy, malodorous (yellow-green) discharge, vulvar irritation

A

Women S/S of Trichomonaisis

39
Q

What STI increases risk of men getting urethritis, epidymitis, and prostatitis ?

A

Trichomonaisis

40
Q

How to dx Trichomonaisis

A

Cervical wet mount, NAAT, APTIMA T, amplified DNA assay.

41
Q

Cervical wet mount smear shows motile protozoa and WBC, with a vaginal Ph of >5 - what STI am I ?

A

Trichomonaisis

42
Q

If you see a “strawberry cervix” What STI would I most likely have contacted ?

A

Trichomonaisis

43
Q

Tx for Trichomonaisis

A

Metronidazole

44
Q

If I have Trichomonaisis, and I have been put on the first line abx tx, what fun substance should I avoid if I don’t want to vomit all over myself

A

Alcohol

45
Q

GNID

A

Neisseria gonorrhea

46
Q

If I have gonorrhea and I am a women what symptoms may I have ?

A

purulent, yellow, or green vaginal discharge, bleeding, pain in intercourse, or pelvic pain.

47
Q

Dx gonorrhea

A

Gonococcal culture & NAAT

48
Q

If you are trying to dx gonorrhea where do you collect swabs

A

women: endocervical men: urethral

49
Q

The tx combo for gonorrhea

A

Ceftriaxine 250 mg IM X1 PLUS azithromycin 1 gram PO x1

50
Q

If I am given Ceftriaxine 250 mg IM X1 PLUS azithromycin 1 gram PO x1, what STI do I most likely have ?

A

Gonorrhea

51
Q

What two STI can be asymptomatic most a lot of the time

A

Gonorrhea and Chlamydia

52
Q

How to Dx chlamydia

A

NAAT

53
Q

If you want to dx a patient with chlamydia where do you do the swabs?

A

Women; vaginal

Men: urethral, rectal, or first catch urine specimen

54
Q

Tx for chlamydia (2 options)

A

Azithromycin 1 gram PO x1 or doxycycline 100 mg PO BID x7 days

55
Q

What are the high risk HPV stereotypes

A

16 and 18

56
Q

What are the low risk HPV stereotypes

A

6 and 11

57
Q

What does HPV 16 and 18 predispose you too?

A

cervical carcinoma CA

58
Q

What does HPV 6 and 11 predispose you too?

A

Genital warts

59
Q

External warts that are flat. popular, or pedunculate lesions, single of multiple and of different sizes

A

HPV

60
Q

If I have wart-like lesions that are asymptomatic what STI should I be tested for ?

A

HPV

61
Q

Dx of HPV

A

Visually inspect the lesions. cytology (pap smear), colposcopy

62
Q

Preventative care for cervical CA and HPV

A

Gardisil vaccine

63
Q

Tx for HPV

A

Podofilox BID 3x week for 16 weeks, Imiquimod cream at bedtime 3x week for 16 weeks

64
Q

DX HIV - initial screening test

A

HIV1 / HIV2 antigen/antibody combination immunoassay

65
Q

DX HIV Second screening if HIV1 / HIV2 antigen/antibody combination immunoassay comes back positive

A

Immunoassay to distinguish between HIV1 and HIV2 antibodies

66
Q

If Immunoassay to distinguish between HIV1 and HIV2 antibodies was inconclusive what test do you run to dx HIV

A

NAAT - the HIV viral load testing

67
Q

Tx for HIV1

A

Two NRTIs + a third drug from another ARV class (INSTI, NNRTI, PI) + PK