Steven Johnson Syndrome AndaToxic Epidermal Necrolysis Flashcards
1
Q
Steven Johnson Syndrome definition
A
Total body blistering and detachment <10%
10% mortality
2
Q
SJS/TEN overlap definition
A
Total body blistering and detachment 10-30%
3
Q
TEN definition
A
Total BSA blistering and detachment 30%
Mortality 30%
4
Q
Most common causes of SJS and TEN
A
Sulfa drugs, anticonvulsants, allopurinol, NSAIDs, ABX
5
Q
S/s of SJS and TEN
A
Fever 102.2, sore throat, conjunctivitis, acute onset of painful/dusky/target like lesions, interstitial/pulmonary involvement
6
Q
Diagnostics for SJS and TENS
(Labs plus procedures)
A
CBC, CMP, LFTs (eosinophils, transminitis)
Frozen skin biopsy
7
Q
SJS and TENS treatment plan
A
Immediate discontinuation of drug, IVF, wound care, infection prevention, ophthalmologic support, respiratory support, prednisone
