Steroids Flashcards
1
Q
A
2
Q
What are the adverse effects of supraphysiologic doses of glucocorticoids?
A
“moon face” ; fat moves from the extremities to the face and trunk.
“buffalo bump”; fat accumulation
Hirsutism, weight gain, muscle wasting, weakness.
Dermatological: acne (steroid acne, bruising, skin thinning)
Hyperglycaemia
Hypertension; sodium retention, potassium loss
Osteoporosis (> bone catabolism, and influences Vit D)
euphoria/ psychosis
exacerabates peptic ulcers (stimulates gastric acid and pepin production - high doses)
children; growth retardation
Reduces TSH and FSH by pituitary gland
