Sterile and non sterile compounding 7

Question 1

Can non-Commercially formulations still be compounded?

Answer 1

yes

Question 2

what should sterile preparations meet?

Answer 2

identity, potency, quality and purity

Question 3

where should sterile preparations be made?

Answer 3

in a designated area

Question 4

can sterile and nonsterile substances be compounded in the same area?

Answer 4

no

Question 5

What is known as the control or the buffer area?

Answer 5

This is where the Laminar flow bench is located, this areas is kept separate from non-sterile compounding.

Question 6

What is the anteroom used for?

Answer 6

used to decontaminate supplies and equipment

Question 7

What are the compounding sterile preparations categories?

Answer 7

Low, Medium and High Risk

Question 8

Which risk involves no more than three commercially available products, and two entries in the sterile compounding bag?

Answer 8

Low risk

Question 9

Which Risk involves, compounding using aseptic manipulations in an ISO class 5 environment?

Answer 9

Low Risk

Question 10

Which Risk involves, pooling multiple vials or containers to prepare a CSP for one or more patients

Answer 10

Medium Risk

Question 11

Which Risk involves a long compounding process

Answer 11

Medium Risk

Question 12

A high risk, contains ; using a non-sterile formulation to prepare CSP, T or F?

Answer 12

True

Question 13

Which risk, poses a major threat when it involves mixing sterile ingredients in non-sterile devices?

Answer 13

High Risk

Question 14

Can compatibility issues arise between a drug and an IV?

Answer 14

yes

Question 15

What are some factors of incompatibility?

Answer 15

visible or chemical changes

Question 16

What does the EPA set?

Answer 16

they set laws, on where you should and can dispose of pharmaceutical waste

Question 17

What are the categories of hazardous waste?

Answer 17

P U K F

Question 18

What are some characteristics of hazardous waste?

Answer 18

toxicity, corrosivity, ignitability and reactivity

Question 19

What is labeled as commercial chemical products?

Answer 19

P and U, this includes drugs like chemotherapeutics agents, warfarin and nicotine

Question 20

hazardous waste should have a seperate controls and have ?

Answer 20

negative pressure room to house engineering controls

Question 21

What are some antimicrobial preservations?

Answer 21

IV solutions and ophthalmics

Question 22

What is the meaning of antimicrobial preservations?

Answer 22

used for bacteriostatic preparations to prevent bacteria from growing

Question 23

What is the meaning of Antioxidants?

Answer 23

prevent oxidation of the component drug

Question 24

What are chelating agents?

Answer 24

they reduce the toxic effect on metals

Question 25

emulsifiers?

Answer 25

used to create a uniformed concentrations of an active drug in a solution

Question 26

pH buffers?

Answer 26

help stabilize a solution against degradation

Question 27

solute?

Answer 27

a substance dissolved in a solvent

Question 28

tonicity agent?

Answer 28

help adjust formulations to an appropriate isotonic range

Question 29

vehicle

Answer 29

serves as solvent

Question 30

What are some single use containers and what does that mean?

Answer 30

they do not contain microbial preservatives, they can be viles and or ampules

Question 31

viles should not be used no more than ____ hours after the initial needle puncture

Answer 31

6

Question 32

open ampules should be stored, True or False?

Answer 32

false; they should not be stored

Question 33

Multiple use containers have what?

Answer 33

antimicrobial preservatives, this allows for withdrawal of contents over a period of time

Question 34

what is the BUD on the multiple use container?

Answer 34

28 days

Question 35

What is the most common glass container that is used in a sterile preparation?

Answer 35

borosilicate