STEP 2 CS CASES Flashcards

1
Q

3 yo M presents with a two-day history of fever and pulling on his right ear. He is otherwise healthy, and his immunizations are up to date. His older sister recently had a cold. The child attends a day care center.

A
Acute otitis media 
URI
 Meningitis
 UTI
 W/U: Physical exam (including pneumatic otoscopy) CBC UA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

4 yo M presents with diarrhea, vomiting, lethargy, weakness, and fever. The child attends a day care center where several children have had similar symptoms.

A
Gastroenteritis (viral, bacterial, parasitic)
Food poisoning 
UTI 
URI 
Volvulus 
Intussusception 
W/U: Physical exam
Stool exam and culture
CBC 
Electrolytes 
UA
urine culture 
AXR
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

5 yo M presents with a six-month history of temper tantrums that last 5-10 minutes and immediately follow a disappointment or a discipline. He has no trouble sleeping, has had no change in appetite, and does not display thesebehaviors when he is at day care.

A
Age-appropriate behavior 
ADHD 
Oppositional defiant disorder 
W/U: Physical exam 
Mental status exam
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

9 yo M presents with a two-year history of angry outbursts both in school and at home. His mother complains that he runs around “as if driven by a motor.” His teacher reports that he cannot sit still in class, regularly interrupts his classmates, and has trouble making friends.

A
Attention-deficit hyperactivity disorder (ADHD) 
Oppositional defiant disorder
Manic episode 
Conduct disorder 
W/U: Physical exam 
Mental status exam
TSH, FT4
EEG
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

12-month-old M presents with fever for the last two days accompanied by a maculopapular rash on his face and body. He has not yet received the MMR vaccine.

A
Measles (or other viral exanthem) 
Rubella 
Roseola 
Fifth disease (parvovirus B19) 
Varicella 
Scarlet fever 
Meningitis 
W/U: Physical exam 
CBC 
Viral antibodies/titers 
Throat swab for culture 
LP
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

12 yo F presents with a two-month history of fi ghting in school, truancy, and breaking curfew. Her parents recently divorced, and she just started school in a new district. Before her parents divorced, she was an average student with no behavioral problems.

A
Adjustment disorder 
Substance intoxication/abuse/dependence 
Manic episode 
Oppositional defiant disorder 
Conduct disorder 
W/U: Physical exam 
Mental status exam 
Urine toxicology
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

15 yo M presents with a one-year history of failing grades, school absenteeism, and legal problems, including shoplifting. His parents report that he spends most of his time alone in his room, adding that when he does go out, it is with a new set of friends.

A
Substance abuse 
Conduct disorder 
Oppositional defiant disorder 
Adjustment disorder 
W/U: Urine toxicology 
Mental status exam
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

17 yo F presents with prolonged, excessive menstrual bleeding occurring irregularly over the past six months.

A

Dysfunctional uterine bleeding
Coagulation disorders (e.g., von Willebrand’s disease, hemophilia)
Cervical cancer
Molar pregnancy
Hypothyroidism
Diabetes mellitus
W/U: Pelvic exam, Urine hCG, Cervical cultures, Pap smear CBC, ESR, glucose, PT/PTT, Prolactin, LH/FSH TSH U/S—pelvis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

17 yo M presents with low back pain that radiates to the left leg and began after he fell on his knee during gym class. He also describes areas of loss of sensation in his left foot. The pain and sensory loss do not match any known distribution. He insists on requesting a week off from school because of his injury.

A
Malingering 
Lumbar muscle strain 
Disk herniation
Knee or leg fracture 
Ankylosing spondylitis 
W/U: 
XR—L-spine/knee 
MRI—L-spine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

18 yo F presents with amenorrhea for the past four months. She has lost 95 pounds and has a history of vigorous exercise and cold intolerance.

A
Anorexia nervosa 
W/U: 
CBC 
TSH 
FT4 
ACTH 
FSH 
LH
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

18 yo M boxer presents with severe LUQ abdominal pain that radiates to the left scapula. He had infectious mononucleosis three weeks ago.

A
Splenic rupture 
Kidney stone 
Rib fracture 
Pneumonia 
Perforated peptic ulcer 
Splenic infarct 
W/U: 
Rectal exam 
CBC
electrolytes 
CXR 
CT—abdomen 
U/S—abdomen
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

18 yo M presents with a burning sensation during urination and urethral discharge. He recently had unprotected sex with a new partner.

A
Urethritis 
Cystitis 
Prostatitis 
W/U: Genital ± rectal exam 
UA 
Urine culture 
Gram stain and culture of urethral discharge 
Chlamydia and gonorrhea PCR
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

18 yo M presents with pain in the interphalangeal joints of both hands. He also has scaly, salmon-pink lesions on the extensor surface of his elbows and knees.

A
Psoriatic arthritis 
Rheumatoid arthritis 
SLE 
W/U: RF, ANA, ESR, CBC 
XR—hands XR—pelvis/sacroiliac joints 
Uric acid
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

18 yo obese F presents with a pulsatile headache, vomiting, and blurred vision for the past 2-3 weeks. She is taking OCPs.

A
Pseudotumor cerebri 
Tension headache 
Migraine headache  
Cluster headache 
Meningitis 
Intracranial venous thrombosis 
Intracranial neoplasm 
W/U: Urine hCG 
CBC 
CT—head 
LP—opening pressure and CSF analysis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

19 yo M c/o receiving messages from his television set. He reports that he did not have many friends in high school. In college, he started to suspect his roommate of bugging the phone. In the same time frame, he stopped going to classes because he felt that his professors were saying horrible things about him that no one else noticed. He rarely showered or left his room and has recently been hearing a voice from his television set telling him to “guard against the evil empire.”

A
Schizophrenia 
Schizoid or schizotypal personality disorder Schizophreniform disorder 
Psychotic disorder due to a general medical condition
Substance-induced psychosis 
Depression with psychotic features 
W/U: Mental status exam 
Urine toxicology 
TSH 
CBC 
Electrolytes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

20-day-old M presents with fever, decreased breast-feeding, and lethargy. He was born at 36 weeks as a result of premature rupture of membranes.

A
Neonatal sepsis 
Meningitis 
Pneumonia 
UTI 
W/U: Physical exam 
CBC
Electrolytes 
UA 
Urine culture 
Blood culture 
CXR 
LP—CSF analysis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

20 yo African-American F presents with acute onset of severe chest pain. She has a history of sickle cell disease and multiple previous hospitalizations for pain and anemia management.

A

Sickle cell disease—pulmonary infarction
Pneumonia
Pulmonary embolism
MI
Pneumothorax
Aortic dissection
W/U: CBC, Reticulocyte count, LDH, peripheral smear, ABG, CXR, CPK-MB, troponin, ECG, CT—chest with IV contrast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

20 yo F presents with nausea, vomiting (especially in the morning), fatigue, and polyuria. Her last menstrual period was six weeks ago, and her breasts are full and tender. She is sexually active with her boyfriend, and they use condoms for contraception.

A
Pregnancy 
Gastritis 
Hypercalcemia 
Diabetes mellitus 
UTI 
Depression 
W/U: Urine hCG, Pelvic exam, U/S—pelvis, CBC, electrolytes, calcium, glucose, UA, urine culture, Baseline Pap smear, cervical cultures, rubella antibody, HIV antibody, hepatitis B surface antigen, and VDRL/RPR
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

20 yo M presents with fatigue, thirst, increased appetite, and polyuria.

A
Diabetes mellitus 
Atypical depression 
Primary polydipsia 
Diabetes insipidus 
W/U: Glucose tolerance test, HbA1c UA CBC, electrolytes, glucose, BUN/Cr
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

20 yo M presents with severe RLQ abdominal pain, nausea, and vomiting. His discomfort started yesterday as a vague pain around the umbilicus. As the pain worsened, it became sharp and migrated to the RLQ. McBurney’s and psoas signs are positive.

A

Acute appendicitis
Gastroenteritis
Diverticulitis
Crohn’s disease
Nephrolithiasis
Volvulus or other intestinal obstruction/perforation
W/U: Rectal exam, CBC, electrolytes, AXR, CT—abdomen U/S—abdomen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

21 yo F presents with acute onset of severe RLQ pain, nausea, and vomiting. She has no fever, urinary symptoms, or vaginal bleeding and has never taken OCPs. Her last menstrual period was regular, and she has no history of STDs.

A
Ovarian torsion 
Appendicitis 
Nephrolithiasis 
Ectopic pregnancy 
Ruptured ovarian cyst 
PID 
Bowel infarction or perforation 
W/U: Pelvic exam, Rectal exam, Urine hCG, UA, CBC, Doppler U/S—pelvis, CT—abdomen, Laparoscopy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

21 yo F presents with several episodes of throbbing left temporal pain that lasts for 2-3 hours. Prior to its onset, she sees fl ashes of light in her right visual fi eld and feels weakness and numbness on the right side of her body for a few minutes. Headaches are often associated with nausea and vomiting. She has a family history of migraine.

A
Migraine (complicated) 
Tension headache 
Cluster headache 
Pseudotumor cerebri 
Trigeminal neuralgia 
CNS vasculitis 
Partial seizure 
Intracranial neoplasm
W/U: CBC, ESR, CT—head, MRI—brain, LP with opening pressure.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

23 yo obese F presents with amenorrhea for six months, facial hair, and infertility for the past three years.

A
Polycystic ovary syndrome 
Thyroid disease 
Hyperprolactinemia 
Pregnancy 
Ovarian or adrenal malignancy 
Premature ovarian failure 
W/U: Pelvic exam, Urine hCG, U/S—pelvis, LH/FSH, TSH, prolactin, Testosterone, DHEAS.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

24 yo F presents with bilateral lower abdominal pain that started with the fi rst day of her menstrual period. The pain is associated with fever and a thick, greenish-yellow vaginal discharge. She has had unprotected sex with multiple sexual partners.

A
PID
Endometriosis 
Dysmenorrhea 
Vaginitis 
Cystitis 
Spontaneous abortion 
Pyelonephritis 
W/U: Pelvic exam, Rectal exam, Urine hCG, Cervical cultures, CBC, ESR, UA, urine culture, and U/S—pelvis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

25 yo F presents with a three-week history of diffi culty falling asleep. She sleeps seven hours per night without nightmares or snoring. She recently began college and is having trouble with her boyfriend. She drinks 3-4 cups of coffee a day.

A

Stress-induced insomnia
Caffeine-induced insomnia
Insomnia with circadian rhythm
sleep disorder Insomnia related to major depressive disorder
W/U: Polysomnography, Mental status exam, Urine toxicology, CBC, TSH.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

25 yo F presents with two weeks of a nonproductive cough. Three weeks ago she had a sore throat and a runny nose.

A
Atypical pneumonia 
Reactive airway disease 
URI-associated ("postinfectious") 
Postnasal drip 
GERD 
W/U: CBC, Induced sputum Gram stain and culture, CXR, IgM detection for Mycoplasma pneumoniae, Urine Legionella antigen
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

25 yo M presents with hemiparesis (after a tonic-clonic seizure) that resolves over a few hours.

A
Todd's paralysis 
TIA 
Stroke 
Complicated migraine 
Malingering 
W/U: CBC, electrolytes, EEG, MRI—brain, Doppler U/S—carotid
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

25 yo M presents with high fever, severe headache, confusion, photophobia, and nuchal rigidity. Kernig’s and Brudzinski’s signs are positive.

A
Meningitis 
Migraine 
Subarachnoid hemorrhage 
Sinusitis/encephalitis 
Intracranial or epidural abscess 
W/U: CBC, CT—head, MRI—brain, LP—CSF analysis (cell count, protein, glucose, Gram stain, PCR for antigens, culture)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

25 yo M presents with RUQ pain, fever, anorexia, nausea, and vomiting. He has dark urine and clay-colored stool.

A
Acute hepatitis 
Acute cholecystitis 
Ascending cholangitis 
Choledocholithiasis 
Pancreatitis 
Acute glomerulonephritis
W/U: Rectal exam, CBC, amylase, lipase, AST/ALT/bilirubin/alkaline phosphatase, UA, Viral hepatitis serologies, U/S—abdomen
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

25 yo M presents with watery diarrhea and abdominal cramps. He was recently in Mexico.

A
Traveler's diarrhea 
Giardiasis 
Amebiasis 
Food poisoning 
Hepatitis A 
W/U: Rectal exam, Stool leukocytes, culture, Giardia antigen, Entamoeba histolytica antigen, Electrolytes, AST/ALT/bilirubin/alkaline phosphatase, Viral hepatitis serology
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

26 yo F presents with a 3-kg weight loss over the past two months, accompanied by early-morning awakening, excessive guilt, and psychomotor retardation. She does not identify a trigger for the depressive episode but reports several weeks of increased energy, sexual promiscuity, irresponsible spending, and racing thoughts approximately six months before her presentation.

A
Bipolar I disorder 
Bipolar II disorder 
Cyclothymic disorder 
Major depressive disorder 
Schizoaffective disorder 
W/U: Physical exam, Mental status exam, Urine toxicology
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

26 yo F presents with sore throat, fever, severe fatigue, and loss of appetite for the past week. She also reports epigastric and LUQ discomfort. She has cervical lymphadenopathy and a rash. Her boyfriend recently experienced similar symptoms.

A

Infectious mononucleosis
Hepatitis Viral or bacterial pharyngitis
Acute HIV infection
Secondary syphilis
W/U: CBC, peripheral smear, Monospot test, Throat culture, AST/ALT/bilirubin/alkaline phosphatase, HIV antibody and viral load, Anti-EBV antibodies, VDRL/RPR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

26 yo M presents after falling and losing consciousness at work. He had rhythmic movements of the limbs, bit his tongue, and lost control of his bladder. He was subsequently confused (as witnessed by his colleagues).

A
Seizure 
Complex tonic-clonic seizure
Convulsive syncope 
Substance abuse/overdose 
Malingering 
Hypoglycemia 
W/U: CBC, electrolytes, glucose, Urine toxicology, EEG, MRI—brain, CT—head, LP—CSF analysis, ECG
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

26 yo M presents with severe right temporal headaches associated with ipsilateral rhinorrhea, eye tearing, and redness. Episodes have occurred at the same time every night for the past week and last for 45 minutes.

A
Cluster headache 
Migraine 
Tension headache 
Sinusitis 
Pseudotumor cerebri 
Trigeminal neuralgia 
Intracranial neoplasm
W/U: CBC, ESR, CT—head, MRI—brain LP
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

26 yo M presents with sore throat, fever, rash, and weight loss. He has a history of IV drug abuse and sharing needles.

A
HIV 
Acute retroviral syndrome 
Infectious mononucleosis 
Hepatitis 
Viral pharyngitis 
Streptococcal tonsillitis/scarlet fever 
Secondary syphilis 
W/U: CBC, Peripheral smear, HIV antibody and viral load CD4 count, Monospot test, Throat culture, VDRL/RPR AST/ALT/bilirubin/alkaline phosphatas
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

27 yo F presents with painful wrists and elbows, a swollen and hot knee joint that is painful on fl exion, a rash on her limbs, and vaginal discharge. She is sexually active with multiple partners and occasionally uses condoms.

A
Disseminated gonorrhea 
Rheumatoid arthritis
SLE 
Psoriatic arthritis 
Reiter's arthritis 
W/U: Knee arthrocentesis and synovial fluid analysis (cell count, Gram stain, culture), ANA, anti-dsDNA, ESR, RF, CBC, Blood and cervical cultures XR—knee
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

28 yo F c/o multiple facial and bodily injuries. She claims that she fell on the stairs. She was hospitalized for some physical injuries seven months ago. She presents with her husband.

A
Domestic violence 
Osteogenesis imperfecta 
Substance abuse 
Consensual violent sexual behavior 
W/U: XR—skeletal survey, CT—maxillofacial, Urine toxicology, CBC
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

28 yo F c/o seeing bugs crawling on her bed over the past two days and reports hearing loud voices when she is alone in her room. She has never experienced symptoms such as these in the past. She recently ingested an unknown substance.

A

Substance-induced psychosis
Brief psychotic disorder
Schizophreniform disorder
Schizophrenia
Psychotic disorder due to a general medical condition
W/U: Urine toxicology, Mental status exam, TSH, CBC, Electrolytes, BUN/Cr, AST/ ALT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

28 yo F presents with a thin, grayish white, foul-smelling vaginal discharge.

A
Bacterial vaginosis 
Vaginitis—candidal 
Vaginitis—trichomonal 
Cervicitis (chlamydia, gonorrhea) 
W/U: Pelvic exam, Wet mount, Cervical cultures, KOH prep ("whiff test"), pH of vaginal fluid
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

28 yo F presents with pain in the interphalangeal joints of her hands together with hair loss and a butterfly rash on her face.

A
Systemic lupus erythematosus (SLE) 
Rheumatoid arthritis 
Psoriatic arthritis 
Parvovirus B19 infection 
W/U: ANA, anti-dsDNA, ESR, C3, C4, rheumatoid factor (RF), CBC, XR—hands UA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

28 yo F presents with pain in the metacarpophalangeal joints of both hands. Her left knee is also painful and red. She has morning joint stiffness that lasts for an hour. Her mother had rheumatoid arthritis.

A

Rheumatoid arthritis SLE Disseminated gonorrhea Arthritis associated with infl ammatory bowel disease Osteoarthritis W/U: ANA, anti-dsDNA, ESR, RF, CBC XR—hands, left knee Cervical culture Arthrocentesis and synovial fl uid analysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

28 yo F who is eight weeks pregnant presents with lower abdominal pain and vaginal bleeding.

A

Spontaneous abortion
Ectopic pregnancy
Molar pregnancy
W/U: Pelvic exam, Urine hCG, U/S—pelvis, CBC, PT/PTT, Quantitative serum hCG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

28 yo M presents with constipation (very hard stool) for the last three weeks. Since his mother died two months ago, he and his father have eaten only junk food.

A
Low-fiber diet 
Irritable bowel syndrome 
Substance abuse (e.g., heroin) 
Depression 
Hypothyroidism 
W/U: Rectal exam, TSH, Electrolytes, Urine toxicology
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

29 yo F presents with amenorrhea for the past six months. She has a history of occasional palpitations and dizziness. She lost her fiancé in a car accident.

A

Anxiety-induced amenorrhea

W/U: CBC, TSH, FT4, ACTH, Urine cortisol level, Progesterone challenge test, FSH/LH/estradiol levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

30 yo F presents with alternating constipation and diarrhea and abdominal pain that is relieved by defecation. She has no nausea, vomiting, weight loss, or blood in her stool.

A

Irritable bowel syndrome
Inflammatory bowel disease
Celiac disease
Chronic pancreatitis
GI parasitic infection (ascariasis, giardiasis)
Lactose intolerance
W/U: Rectal exam, stool for occult blood, CBC, Electrolytes Stool for ova and parasitology, AXR, CT—abdomen/pelvis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

30 yo F presents with a thick, white, cottage cheese-like, odorless Vaginal discharge and vaginal itching.

A

Vaginitis—candidal
Bacterial vaginosis
Vaginitis—trichomonal
W/U: Pelvic exam, KOH prep (“whiff test”), Wet mount Cervical cultures, pH of vaginal fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

30 yo F presents with frontal headache, fever, and nasal discharge. There is pain on palpation of the frontal and maxillary sinuses. She has a history of sinusitis.

A
Sinusitis 
Migraine 
Tension headache 
Meningitis 
Intracranial neoplasm
W/U: CBC, XR—sinus, CT—sinus, LP
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

30 yo F presents with multiple facial and physical injuries. She was attacked and raped by two men.

A

Rape
W/U: Pelvic exam, Urine hCG, Wet mount, KOH prep, cervical cultures, XR—skeletal survey, CBC, HIV antibody, Viral hepatitis serologies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

30 yo F presents with periumbilical pain for six months. The pain never awakens her from sleep. It is relieved by defecation and worsens when she is upset. She has alternating constipation and diarrhea but no nausea, vomiting, weight loss, or anorexia.

A

Irritable bowel syndrome
Crohn’s disease
Celiac disease
Chronic pancreatitis
GI parasitic infection (amebiasis, giardiasis)
Endometriosis
W/U: Rectal exam, stool for occult blood, Pelvic exam, Urine hCG, CBC, Electrolytes, CT—abdomen/pelvis, Stool for ova and parasitology, Entamoeba histolytica antigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

30 yo F presents with watery diarrhea and abdominal cramping and bloating. Her symptoms are aggravated by milk ingestion and are relieved by fasting.

A
Lactose intolerance 
Gastroenteritis 
Inflammatory bowel disease
Irritable bowel syndrome 
Hyperthyroidism 
W/U: Rectal exam, Stool exam, Hydrogen breath test, TSH
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

30 yo F presents with weakness, loss of sensation, and tingling in her left leg that started this morning. She is also experiencing right eye pain, decreased vision, and double vision. She reports feeling “electric shocks” down her spine upon fl exing her head.

A
Multiple sclerosis 
Stroke 
Conversion disorder 
Malingering 
CNS tumor 
Neurosyphilis 
Syringomyelia 
CNS vasculitis 
W/U: CBC, ESR, VDRL/RPR, MRI—brain, LP—CSF analysis, Retinal evoked potentials
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

30 yo F presents with wrist pain and a black eye after tripping, falling, and hitting her head on the edge of a table. She looks anxious and gives an inconsistent story.

A

Domestic violence
Factitious disorder
Substance abuse
W/U: XR—wrist, CT—head, Urine toxicology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

30 yo F secretary presents with wrist pain and a sensation of numbness and burning in her palm and the fi rst, second, and third fingers of her right hand. The pain worsens at night and is relieved by loose shaking of the hand. There is sensory loss in the same fi ngers. Exam reveals a positive Tinel’s sign.

A

Carpal tunnel syndrome
Median nerve compression in forearm or arm
Radiculopathy of nerve roots C6 and C7 in cervical spine W/U: Nerve conduction study, EMG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

30 yo M presents with night sweats, cough, and swollen glands of one month’s duration.

A
Tuberculosis 
Acute HIV infection 
Lymphoma 
Leukemia 
Hyperthyroidism 
W/U: PPD, CBC, CXR, Sputum Gram stain, acid-fast stain and culture, HIV antibody, TSH, FT4
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

30 yo M presents with shortness of breath, cough, and wheezing that worsen in cold air. He has had several such episodes over the past four months.

A
Asthma 
GERD 
Bronchitis 
Pneumonitis 
Foreign body 
W/U: CBC, CXR, Peak flow measurement PFTs, Methacholine challenge test
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

32 yo F presents with sudden onset of left lower abdominal pain that radiates to the scapula and back and is associated with vaginal bleeding. Her last menstrual period was fi ve weeks ago. She has a history of PID and unprotected intercourse.

A
Ectopic pregnancy 
Ruptured ovarian cyst 
Ovarian torsion 
PID 
W/U: Pelvic exam, Urine hCG, Cervical cultures, U/S—pelvis, Quantitative serum hCG
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

33 yo F c/o three weeks of fatigue and trouble sleeping. She states that she falls asleep easily but wakes up at 3 A.M. and cannot return to sleep. She also reports an unintentional weight loss of 3.5 kg along with an inability to enjoy the things she once liked to do.

A

Insomnia related to major depressive disorder
Primary hypersomnia
Insomnia with circadian rhythm sleep disorder
W/U: Mental status exam, TSH, CBC, Polysomnography

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

33 yo F presents with ascending loss of strength in her lower legs over the past two weeks. She had a recent URI.

A
Guillain-Barré syndrome 
Multiple sclerosis 
Polymyositis 
Myasthenia gravis 
Peripheral neuropathy 
Tumor in the vertebral canal 
W/U: CBC, electrolytes, CPK, LP—CSF analysis, MRI—spine EMG/nerve conduction study, Tensilon test, Serum B12
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

33 yo F presents with rectal bleeding and diarrhea for the past week. She has had lower abdominal pain and tenesmus for several months.

A
Ulcerative colitis 
Crohn's disease 
Proctitis 
Anal fissure 
Hemorrhoids 
Diverticulosis 
Dysentery 
W/U: Rectal exam, CBC, PT/PTT, AXR, Colonoscopy, CT—abdomen/pelvis, Barium enema
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

33 yo M presents with watery diarrhea, diffuse abdominal pain, and weight loss over the past three weeks. He has not responded to antibiotics.

A
Crohn's disease 
Gastroenteritis 
Ulcerative colitis 
Celiac disease 
Pseudomembranous colitis 
Hyperthyroidism 
Small bowel lymphoma 
Carcinoid 
W/U: Rectal exam, Stool exam and culture, CBC, electrolytes, TSH, CT—abdomen, Colonoscopy, Small bowel serie,s Urinary 5-HIAA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

33 yo M presents with watery diarrhea, vomiting, and diffuse abdominal pain that began yesterday. He also reports feeling hot. Several of his coworkers are also ill.

A

Infectious diarrhea (gastroenteritis)—bacterial, viral, parasitic, protozoal
Food poisoning
Inflammatory bowel disease
W/U: Rectal exam, stool for occult blood, Stool leukocytes and culture, CBC, Electrolytes, CT—abdomen/pelvis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
62
Q

34 yo F nurse presents with worsening cough of six weeks’ duration together with weight loss, fatigue, night sweats, and fever. She has a history of contact with tuberculosis patients at work.

A
Tuberculosis 
Pneumonia 
Lung abscess 
Vasculitis 
Lymphoma 
Metastatic cancer 
HIV/AIDS 
Sarcoidosis 
W/U: CBC, PPD, Sputum Gram stain, acid-fast stain, and culture, CXR, CT—chest, Bronchoscopy, HIV antibody
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
63
Q

34 yo F presents with retrosternal stabbing chest pain that improves when she leans forward and worsens with deep inspiration. She had a URI one week ago.

A
Pericarditis 
Aortic dissection 
MI 
Costochondritis 
GERD 
Esophageal rupture 
W/U: ECG, CPK-MB, troponin, CXR, Echocardiography, CBC, Upper endoscopy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
64
Q

34 yo F presents with stabbing chest pain that worsens with deep inspiration and is relieved by aspirin. She had a URI one week ago. Chest wall tenderness is noted.

A
Costochondritis 
Pneumonia 
MI 
Pulmonary embolism 
Pericarditis 
Muscle strain 
W/U: ECG, CPK-MB, troponin, CXR, CBC
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
65
Q

35 yo F presents with a malodorous, profuse, frothy, greenish vaginal discharge with intense vaginal itching and discomfort.

A
Vaginitis—trichomonal 
Vaginitis—candidal 
Bacterial vaginosis 
Cervicitis (chlamydia, gonorrhea) 
W/U: Pelvic exam, Wet mount, Cervical cultures, pH of the vaginal fluid, KOH prep ("whiff test")
66
Q

35 yo F presents with amenorrhea, cold intolerance, coarse hair, weight loss, and fatigue. She has a history of abruptio placentae followed by hypovolemic shock and failure of lactation two years ago.

A
Sheehan's syndrome 
Premature ovarian failure 
Pituitary tumor 
Thyroid disease 
Asherman's syndrome 
W/U: Pelvic exam, Urine hCG, CBC, LH/FSH, prolactin TSH, FT4, ACTH, MRI—brain, Hysteroscopy
67
Q

35 yo F presents with amenorrhea, galactorrhea, visual field defects, and headaches for the past six months.

A
Amenorrhea secondary to prolactinoma 
Pregnancy 
Thyroid disease 
Premature ovarian failure 
Pituitary tumor 
W/U: Pelvic and breast exam Urine hCG Prolactin LH/FSH, TSH MRI—brain
68
Q

35 yo F presents with intermittent episodes of vertigo, tinnitus, nausea, and hearing loss over the past week.

A

Ménière’s disease Vestibular neuronitis Labyrinthitis Benign positional vertigo Acoustic neuroma W/U: CBC VDRL/RPR (syphilis is a cause of Ménière’s disease) MRI—brain

69
Q

35 yo M policeman c/o feeling tired and sleepy during the day. He changed to the night shift last week.

A

Sleep deprivation
Sleep apnea
Depression Anemia
W/U: CBC, Nocturnal pulse oximetry, Polysomnography

70
Q

35 yo M presents with burning epigastric pain that starts 2-3 hours after meals. The pain is relieved by food and antacids.

A
Peptic ulcer disease 
Gastritis 
GERD 
Cholecystitis 
Chronic pancreatitis 
Mesenteric ischemia 
W/U: Rectal exam, Amylase, lipase, lactate AST/ALT/bilirubin/alkaline phosphatase, Endoscopy (including H. pylori testing), Upper GI series
71
Q

35 yo M presents with painless hematuria. He has a family history of kidney problems.

A

Polycystic kidney disease
Nephrolithiasis
Acute glomerulonephritis (e.g., IgA nephropathy)
UTI
Coagulation disorder
Bladder cancer
W/U: Genitourinary exam, UA, BUN/Cr, PSA, CBC, PT/PTT, U/S—renal, CT—abdomen/pelvis, IVP

72
Q

35 yo M presents with shortness of breath and cough. He has had unprotected sex with multiple sexual partners and was recently exposed to a patient with active tuberculosis.

A

Tuberculosis
Pneumonia (including Pneumocystis jiroveci)
Bronchitis
CHF (cardiomyopathy)
Asthma
Acute HIV infection
W/U: CBC, PPD, Sputum Gram stain, acid-fast stain, silver stain, and culture, CXR, HIV antibody

73
Q

35 yo M presents with sudden severe headache, vomiting, confusion, left hemiplegia, and nuchal rigidity.

A
DDX: 
1 - Subarachnoid hemorrhage 
2 - Migraine 
3 - Meningitis/encephalitis 
4 - Intracranial hemorrhage 
5 - Intracranial neoplasm, 
vertebral a. dissection, intracranial venous thrombosis, acute htn 
W/U: 1 - CBC, PT/PTT, CT head w/o contrast, MRI/MRA brain 3 - LP
74
Q

37 yo F presents with dyspareunia, inability to conceive, and dysmenorrhea.

A
Endometriosis 
Cervicitis 
Vaginismus 
Vulvodynia 
PID 
Depression 
Domestic violence 
W/U: Pelvic exam, Wet mount, KOH prep, cervical cultures, U/S—pelvis, Laparoscopy
75
Q

37 yo M presents with severe epigastric pain, nausea, vomiting, and mild fever. He appears toxic. He has a history of intermittent epigastric pain that is relieved by food and antacids. He also smokes heavily and takes aspirin on a regular basis.

A
Peptic ulcer perforation 
Acute pancreatitis 
Hepatitis 
Cholecystitis 
Choledocholithiasis 
Mesenteric ischemia 
W/U: Rectal exam, CBC, electrolytes, amylase, lipase, lactate AST/ALT/bilirubin/alkaline phosphatase, AXR, Upright CXR, Endoscopy (including H. pylori testing)
76
Q

38 yo M presents with dysphagia and pain on swallowing solids more than liquids. Exam reveals oral thrush.

A
Esophagitis (CMV, HSV, pillinduced) 
Systemic sclerosis 
GERD 
Esophageal stricture 
Zenker's diverticulum 
W/U: CBC, Endoscopy, Barium swallow, HIV antibody CD4 count
77
Q

40 yo F c/o feeling tired, hopeless, and worthless and of having suicidal thoughts. She recently discovered that her husband is homosexual.

A
Depression 
Adjustment disorder 
Hypothyroidism 
Anemia 
W/U: CBC, TSH, HIV/STD testing (given husband's possible risk factors)
78
Q

40 yo F presents with amenorrhea, morning nausea and vomiting, fatigue, and polyuria. Her last menstrual period was six weeks ago, and her breasts are full and tender. She uses the rhythm method for contraception.

A
Pregnancy 
Anovulatory cycle 
Hyperprolactinemia 
UTI 
Thyroid disease 
W/U: Pelvic exam, Urine hCG, U/S—pelvis, CBC, electrolytes, UA, urine culture, Prolactin, TSH, Baseline Pap smear, cervical cultures, rubella antibody, HIV antibody, hepatitis B surface antigen, and VDRL/ RPR
79
Q

40 yo F presents with epigastric pain and coffee-ground emesis. She has a history of rheumatoid arthritis that has been treated with aspirin. She is an alcoholic.

A
Gastritis 
Bleeding peptic ulcer 
Gastric cancer 
Esophageal varices 
Mallory-Weiss tear 
W/U: Rectal exam, CBC, electrolytes, AST/ALT/bilirubin/alkaline phosphatase, Barium swallow, Endoscopy
80
Q

40 yo F presents with fatigue, weight gain, sleepiness, cold intolerance, constipation, and dry skin.

A
Hypothyroidism 
Depression 
Diabetes 
Anemia 
W/U: TSH, FT3, FT4, CBC, Glucose, HbA1c
81
Q

40 yo F presents with occasional double vision and droopy eyelids at night with normalization by morning.

A

Myasthenia gravis
Horner’s syndrome
Multiple sclerosis
Intracranial tumor compressing CN III, IV, or VI
Amyotrophic lateral sclerosis
W/U: Tensilon test, ACh receptor antibodies (in serum), CXR, CT—chest, MRI—brain, EMG

82
Q

40 yo F presents with watery diarrhea and abdominal cramps. Last week she was on antibiotics for a UTI.

A

Pseudomembranous (Clostridium difficile) colitis
Gastroenteritis
Cryptosporidiosis
Food poisoning
Inflammatory bowel disease
W/U: Rectal exam, Stool leukocytes, culture, occult blood, C. difficile toxin in stool, Electrolytes.

83
Q

40 yo M presents with crampy abdominal pain, vomiting, abdominal distention, and inability to pass fl atus or stool. He has a history of multiple abdominal surgeries.

A
Intestinal obstruction 
Small bowel or colon cancer 
Volvulus of the bowel 
Gastroenteritis 
Food poisoning 
Ileus 
Hernia 
W/U: Rectal exam, CBC, electrolytes, AXR, CT—abdomen/pelvis, CXR
84
Q

40 yo M presents with pain in the right groin after a motor vehicle accident. His right leg is fl exed at the hip, adducted, and internally rotated.

A

Hip dislocation—traumatic
Hip fracture
W/U: XR—hip, CT or MRI—hip, CBC, PT/PTT, Blood type and cross-match, Urine toxicology, and blood alcohol level

85
Q

41 yo obese F presents with RUQ abdominal pain that radiates to the right scapula and is associated with nausea, vomiting, and a fever of 101.5°F. The pain started after she had eaten fatty food. She has had similar but less intense episodes that lasted a few hours. Exam reveals positive Murphy’s sign.

A
Acute cholecystitis 
Hepatitis 
Choledocholithiasis 
Ascending cholangitis 
Peptic ulcer disease 
Fitz-Hugh-Curtis syndrome 
W/U: Rectal exam, CBC, AST/ALT/bilirubin/alkaline phosphatase, U/S—abdomen, HIDA scan
86
Q

42 yo F presents with a 7-kg weight loss over the past two months. She has a fi ne tremor, and her pulse is 112.

A
Hyperthyroidism 
Cancer 
HIV infection 
Dieting/diet drugs 
Anorexia nervosa 
Malabsorption 
W/U: TSH, FT4, CBC, electrolytes, HIV antibody, Urine toxicology
87
Q

42 yo F presents with a four-week history of excessive fatigue, insomnia, and anhedonia. She states that she thinks constantly about death. She has suffered fi ve similar episodes in the past, the fi rst in her 20s, and has made two previous suicide attempts. She further admits to increased alcohol use in the past month.

A

Major depressive disorder
Substance-induced mood disorder
Dysthymic disorder
W/U: Physical exam, Mental status exam, Blood alcohol level, TSH, CBC, Urine toxicology

88
Q

43 yo obese F presents with RUQ abdominal pain, fever, and jaundice. She was diagnosed with asymptomatic gallstones one year ago.

A
Ascending cholangitis 
Acute cholecystitis 
Hepatitis 
Choledocholithiasis 
Sclerosing cholangitis 
Fitz-Hugh-Curtis syndrome 
W/U: Rectal exam, CBC, AST/ALT/bilirubin/alkaline phosphatase, Viral hepatitis serologies, U/S—abdomen, MRCP, ERCP
89
Q

44 yo F c/o dizziness on moving her head to the left. She feels that the room is spinning around her head. Tilt test results in nystagmus and nausea.

A
Benign positional vertigo 
Vestibular neuronitis 
Labyrinthitis 
Ménière's disease 
W/U: MRI—brain, Audiogram
90
Q

44 yo F presents with a weight gain of > 11 kg over the past two months. She quit smoking three months ago and is on amitriptyline for depression. She also reports cold intolerance and constipation.

A
Smoking cessation 
Drug side effect 
Hypothyroidism 
Cushing's syndrome 
Polycystic ovary syndrome 
Diabetes mellitus 
Atypical depression 
W/U: CBC, electrolytes, glucose, TSH, 24-hour urine free cortisol, Dexamethasone suppression test
91
Q

44 yo M presents with fatigue, insomnia, and nightmares about a murder that he witnessed in a mall one year ago. Since then, he has avoided that mall and has not gone out at night.

A
Post-traumatic stress disorder (PTSD) 
Depression 
Generalized anxiety disorder 
Psychotic or delusional disorder 
Hypothyroidism 
W/U: CBC, TSH, Calcium, Urine toxicology
92
Q

45 yo diabetic F presents with dysuria, urinary frequency, fever, chills, and nausea over the past three days. There is left CVA tenderness on exam.

A
Acute pyelonephritis 
Nephrolithiasis 
Renal cell carcinoma 
Lower UTI (cystitis, urethritis) 
W/U: UA, Urine culture and sensitivity, CBC, BUN/Cr, U/S—renal, CT—abdomen
93
Q

45 yo F presents with a retrosternal burning sensation that occurs after heavy meals and when lying down. Her symptoms are relieved by antacids.

A
GERD 
Esophagitis 
Peptic ulcer disease 
Esophageal spasm 
MI 
Angina 
W/U: ECG, Barium swallow, Upper endoscopy, Esophageal pH monitoring
94
Q

45 yo F presents with coffee-ground emesis for the last three days. Her stool is dark and tarry. She has a history of intermittent epigastric pain that is relieved by food and antacids.

A
Bleeding peptic ulcer 
Gastritis 
Gastric cancer 
Esophageal varices 
W/U: Rectal exam, CBC, electrolytes, AST/ALT/bilirubin/alkaline phosphatase, Endoscopy (including H. pylori testing if ulcer is confirmed)
95
Q

45 yo F presents with dysphagia for two weeks together with fatigue and a craving for ice and clay.

A
Plummer-Vinson syndrome 
Esophageal cancer 
Esophagitis 
Achalasia 
Systemic sclerosis 
Mitral valve stenosis 
W/U: CBC, Serum iron, ferritin, TIBC, Barium swallow, Endoscopy
96
Q

45 yo F presents with low back pain that radiates to the lateral aspect of her left foot. Straight leg raising is positive. Thepatient is unable to tiptoe.

A

Disk herniation
Lumbar muscle strain
Tumor in the vertebral canal
W/U: XR—L-spine MRI—L-spine

97
Q

45 yo F presents with low back pain that started after she cleaned her house. The pain does not radiate, and there is no sensory deficit or weakness in her legs. Paraspinal muscle tenderness and spasm are also noted.

A
Lumbar muscle strain 
Disk herniation 
Abdominal aortic aneurysm 
Vertebral compression fracture 
W/U: XR—L-spine
98
Q

45 yo F presents with right calf pain. Her calf is tender, warm, red, and swollen compared to the left side. She was started on OCPs two months ago for dysfunctional uterine bleeding.

A
DVT 
Baker's cyst rupture 
Myositis 
Cellulitis 
Superficial venous thrombosis
W/U: Doppler, U/S—right leg, CBC, CPK, D-dimer, PT, aPTT, fibrinogen, XR—right leg
99
Q

45 yo G5P5 F presents with postcoital bleeding. She is a cigarette smoker and takes OCPs.

A

Cervical cancer
Cervical polyp
Cervicitis Trauma (e.g., cervical laceration)
W/U: Pelvic exam, Pap smear, Colposcopy and biopsy

100
Q

45 yo M presents with pain in the lower back and legs during prolonged standing and walking. The pain is relieved by sitting and leaning forward (e.g., pushing a grocery cart).

A
Lumbar spinal stenosis 
Lumbar muscle strain 
Tumor in the vertebral canal 
Peripheral vascular disease 
W/U: XR—L-spine, MRI—L-spine (preferred), CT—L-spine, Ankle-brachial index
101
Q

45 yo M presents with right knee pain with swelling and redness.

A
Septic arthritis 
Gout 
Pseudogout 
Lyme arthritis 
Trauma 
Reiter's arthritis 
W/U: CBC, Knee arthrocentesis and synovial fluid analysis, Blood and urethral cultures, XR—knee, Uric acid, Lyme antibody
102
Q

45 yo M presents with sudden onset of colicky right-sided fl ank pain that radiates to the testicles, accompanied by nausea, vomiting, hematuria, and CVA tenderness.

A
Nephrolithiasis 
Renal cell carcinoma 
Pyelonephritis 
GI etiology (e.g., appendicitis) 
W/U: Rectal exam, UA, Urine culture and sensitivity, BUN/Cr CT—abdomen, U/S—renal IVP
103
Q

46 yo F presents with fever and sore throat.

A
Pharyngitis (bacterial or viral) 
Mycoplasma pneumonia 
Acute HIV infection 
Infectious mononucleosis 
W/U: Throat swab for culture and rapid streptococcal antigen, Monospot test, CBC, HIV antibody and viral load
104
Q

47 yo M presents with impotence that started three months ago. He has hypertension and was started on atenolol four months ago. He also has diabetes and is on insulin.

A
Drug-related ED 
ED caused by hypertension 
ED caused by diabetes mellitus 
Psychogenic ED 
Peyronie's disease 
W/U: Genital exam, Rectal exam, Glucose, CBC
105
Q

48 yo F presents with amenorrhea for the past six months accompanied by hot fl ashes, night sweats, emotional lability, and dyspareunia.

A
Menopause 
Pregnancy
Pituitary tumor 
Thyroid disease 
W/U: Pelvic exam, Urine hCG, LH/FSH, TSH, prolactin, testosterone, DHEAS, CBC, MRI—brain
106
Q

48 yo F presents with a one-week history of auditory hallucinations, stating, “I am worthless” and “I should kill myself.” She also reports a two-week history of weight loss, early-morning awakening, decreased motivation, and overwhelming feelings of guilt.

A

Schizoaffective disorder
Mood disorder with psychotic features
Schizophrenia
Schizophreniform disorder
Psychotic disorder due to a general medical condition
W/U: Mental status exam, Beck Depression Inventory, TSH, CBC, Electrolytes

107
Q

48 yo F presents with dysphagia for both solid and liquid foods that has slowly progressed in severity over the past year. It is associated with regurgitation of undigested food, especially at night.

A
Achalasia 
Plummer-Vinson syndrome 
Esophageal cancer 
Esophagitis 
Systemic sclerosis 
Mitral valve stenosis 
Esophageal stricture 
Zenker's diverticulum 
W/U: CXR, Endoscopy, Barium swallow, Esophageal manometry
108
Q

50 yo F presents with recurrent episodes of bilateral squeezing headaches that occur 3-4 times a week, typically toward the end of her work day. She is experiencing signifi cant stress in her life.

A
Tension headache 
Migraine 
Depression 
Caffeine or analgesic withdrawal 
Hypertension 
Cluster headache 
Pseudotumor cerebri 
Intracranial neoplasm 
W/U: CBC, Electrolytes, ESR, CT—head, LP
109
Q

50 yo M presents with a cough that is exacerbated by lying down at night and improved by propping up on three pillows. He also reports exertional dyspnea.

A
CHF 
Cardiac valvular disease 
GERD 
Pulmonary fibrosis 
COPD 
Postnasal drip 
W/U: CBC, CXR, ECG, Echocardiography, PFTs, BNP
110
Q

50 yo M presents with right shoulder pain after falling onto his outstretched hand while skiing. He noticed deformity of his shoulder and had to hold his right arm.

A

Shoulder dislocation
Fracture of the humerus
Rotator cuff injury
W/U: XR—shoulder, XR—arm, MRI—shoulder

111
Q

50 yo obese F presents with fatigue and daytime sleepiness. She snores heavily and naps 3-4 times per day but never feels refreshed. She also has hypertension.

A
Obstructive sleep apnea 
Hypothyroidism 
Chronic fatigue syndrome 
Narcolepsy 
W/U: CBC, TSH, Nocturnal pulse oximetry, Polysomnography, ECG
112
Q

54 yo F c/o painful intercourse. Her last menstrual period was nine months ago. She has hot fl ashes.

A
Atrophic vaginitis 
Endometriosis 
Cervicitis 
Depression 
Domestic abuse 
W/U: Pelvic exam, Wet mount, KOH prep, cervical cultures U/S—pelvis
113
Q

55 yo F c/o dizziness for the past day. She feels faint and has severe diarrhea that started two days ago. She takes furosemide for her hypertension.

A

Orthostatic hypotension due to dehydration (diarrhea, diuretic use)
Vestibular neuronitis
Labyrinthitis
Benign positional vertigo
Vertebrobasilar insufficiency
W/U: Orthostatic vital signs, CBC, Electrolytes, Stool exam (occult blood, fecal leukocytes)

114
Q

55 yo F c/o dizziness that started this morning and of “not hearing well.” She feels nauseated and has vomited once in the past day. She had a URI two days ago.

A
Labyrinthitis 
Vestibular neuronitis 
Ménière's disease 
Acoustic neuroma 
Vertebrobasilar insufficiency 
W/U: Audiogram, Electronystagmography, MRI/MRA—brain
115
Q

55 yo F c/o dizziness that started this morning. She is nauseated and has vomited once in the past day. She had a URI two days ago and has experienced no hearing loss.

A

Vestibular neuronitis
Labyrinthitis
Ménière’s disease
Benign positional vertigo
Vertigo associated with cervical spine disease/injury
Vertebrobasilar insufficiency
W/U: CBC, Electrolytes, Electronystagmography, MRI/MRA—brain

116
Q

55 yo F presents with gradual altered mental status and headache. Two weeks ago she slipped, hit her head on the ground, and lost consciousness for two minutes.

A
Subdural hematoma 
SIADH (causing hyponatremia) 
Creutzfeldt-Jakob disease 
Intracranial neoplasm 
W/U: Electrolytes, CT—head, MRI—brain, LP
117
Q

55 yo M c/o falling after feeling dizzy and unsteady. He experienced transient LOC. He has hypertension and is on numerous antihypertensive drugs.

A

Drug-induced orthostatic hypotension (causing syncope)
Cardiac arrhythmia
Syncope (vasovagal, other causes)
Stroke
MI
Pulmonary embolism
W/U: Orthostatic vital signs, CBC, Electrolytes, CT—head, ECG, V/Q scan, CT—chest with IV contrast

118
Q

55 yo M presents with a rapidly progressive change in mental status, inability to concentrate, and memory impairment for the past two months. His symptoms are associated with myoclonus and ataxia.

A
Creutzfeldt-Jakob disease 
Vascular dementia 
Lewy body dementia 
Wernicke's encephalopathy 
Normal pressure hydrocephalus 
Chronic subdural hematoma 
Intracranial neoplasm 
Depression 
Delirium 
B12 deficiency 
Neurosyphilis 
W/U: CBC, electrolytes, calcium, Serum B12, VDRL/RPR, MRI—brain (preferred), CT—head, EEG, LP—CSF analysis, Brain biopsy
119
Q

55 yo M presents with crampy bilateral thigh and calf pain, fatigue, and dark urine. He is on simvastatin and clofibrate for hyperlipidemia.

A

Rhabdomyolysis due to simvastatin or clofibrate
Polymyositis
Inclusion body myositis
Thyroid disease
W/U: CBC, CPK, Aldolase, UA, Urine myoglobin, TSH

120
Q

55 yo M presents with fatigue, weight loss, and constipation. He has a family history of colon cancer.

A
Colon cancer 
Hypothyroidism 
Renal failure 
Hypercalcemia 
Depression 
W/U: Rectal exam, stool for occult blood, CBC, electrolytes, calcium, BUN/Cr, AST/ALT, TSH Colonoscopy, Barium enema
121
Q

55 yo M presents with fl ank pain and blood in his urine without dysuria. He has experienced weight loss and fever over the past two months.

A
Renal cell carcinoma 
Bladder cancer 
Nephrolithiasis 
Acute glomerulonephritis 
Pyelonephritis 
Prostate cancer 
 W/U: Genitourinary and rectal exam, UA, urine cytology, BUN/Cr, PSA, CBC, PT/PTT U/S—renal CT—abdomen/pelvis, IVP
122
Q

55 yo M presents with increased dyspnea and sputum production over the past three days. He has COPD and stopped using his inhalers last week. He also stopped smoking two days ago.

A
COPD exacerbation (bronchitis) 
Lung cancer 
Pneumonia 
URI 
CHF 
W/U: CBC, CXR, PFTs, Sputum Gram stain and culture, CT—chest
123
Q

55 yo M presents with pain in the elbow when he plays tennis. His grip is impaired as a result of the pain. There is tenderness over the lateral epicondyle as well as pain on resisted wrist dorsiflexion (Cozen’s test) with the elbow in extension.

A

Tennis elbow (lateral epicondylitis)
Stress fracture
W/U: XR—arm, Bone scan, MRI—elbow

124
Q

55 yo M presents with retrosternal squeezing pain that lasts for two minutes and occurs with exercise. It is relieved by rest and is not related to food intake.

A

Angina
Esophageal spasm
Esophagitis
W/U: ECG, CPK-MB, troponin, CXR, CBC, electrolytes, Exercise stress test, Upper endoscopy/pH monitor, Cardiac catheterization

125
Q

55 yo M presents with sudden onset of severe chest pain that radiates to the back. He has a history of uncontrolled hypertension.

A
Aortic dissection 
MI 
Pericarditis 
Esophageal rupture 
Esophageal spasm 
GERD 
Pancreatitis 
Fat embolism 
W/U: ECG, CPK-MB, troponin CXR, CBC, amylase, lipase, Transesophageal echocardiography (TEE), MRI/MRA—aorta Aortic angiography, Upper endoscopy
126
Q

55 yo M presents with tingling and numbness in the hands and feet (gloveand- stocking distribution) over the past two months. He has a history of diabetes mellitus, hypertension, and alcoholism. There is decreased soft touch, vibratory, and position sense in the feet.

A
Diabetic peripheral neuropathy 
Alcoholic peripheral neuropathy
 B12 deficiency 
Hypocalcemia 
Hyperventilation 
Paraproteinemia/myeloma 
W/U: HbA1c, ESR, Calcium, Serum B12, Serum and urine protein electrophoresis
127
Q

55 yo obese M presents with several months of poor sleep and daytime fatigue. His wife reports that he snores loudly.

A

Obstructive sleep apnea
Daytime fatigue in primary hypersomnia
Insomnia with circadian rhythm sleep disorder
Insomnia related to major depressive disorder
W/U: CBC, TSH, Polysomnography, ECG

128
Q

56 yo F presents with shortness of breath as well as with a productive cough that has occurred over the past two years for at least three months each year. She is a heavy smoker.

A
COPD—chronic bronchitis 
Bronchiectasis 
Lung cancer 
Tuberculosis 
W/U: CBC, Sputum Gram stain and culture, CXR, PFTs, CT—chest PPD
129
Q

56 yo M presents with severe midepigastric abdominal pain that radiates to the back and improves when he leans forward. He also reports anorexia, nausea, and vomiting. He is an alcoholic and has spent the past three days binge drinking.

A
Acute pancreatitis 
Peptic ulcer disease 
Cholecystitis/choledocholithiasis 
Gastritis 
Abdominal aortic aneurysm 
Mesenteric ischemia 
Alcoholic hepatitis 
Mallory-Weiss tear 
W/U: Rectal exam, CBC, electrolytes, BUN/Cr, amylase, lipase, AST/ALT/bilirubin/alkaline phosphatase, U/S—abdomen, CT—abdomen, Upper endoscopy, ECG
130
Q

56 yo obese F presents with right knee stiffness and pain that increases with movement. Her symptoms have gradually worsened over the past 10 years. She noticed swelling and deformity of the joint and is having diffi culty walking.

A

Osteoarthritis
Pseudogout
Gout Meniscal or ligament damage
W/U: XR—knee, CBC, ESR, Knee arthrocentesis and synovial fluid analysis (cell count, Gram stain, culture, crystals), MRI—knee

131
Q

57 yo M c/o daily pain in the right cheek over the past month. The pain is electric and stabbing in character and occurs while he is shaving. Each episode lasts 2-4 minutes.

A
Trigeminal neuralgia 
Tension headache 
Migraine 
Cluster headache 
TMJ dysfunction 
Intracranial neoplasm 
W/U: CBC, ESR, MRI—brain
132
Q

58 yo M presents with bright red blood per rectum and chronic constipation. He consumes a low-fiber diet.

A
Diverticulosis 
Anal fissure 
Hemorrhoids 
Angiodysplasia 
Colorectal cancer 
W/U: Rectal exam, CBC, PT/PTT, Electrolytes, Colonoscopy, CT—abdomen/pelvis
133
Q

58 yo M presents with pleuritic chest pain, fever, chills, and cough with purulent yellow sputum. He is a heavy smoker with COPD.

A
Pneumonia 
Bronchitis 
Lung abscess 
Lung cancer 
Tuberculosis 
Pericarditis 
W/U: CBC, Sputum Gram stain and culture, CXR, CT—chest ECG, PPD
134
Q

60 yo F c/o left arm pain that started while she was swimming and was relieved by rest.

A

Angina/MI
Tendonitis
Osteoarthritis Shoulder dislocation
W/U: CPK-MB, troponin, ECG, CBC, ESR, XR—shoulder, CXR, Echocardiography, Stress test

135
Q

60 yo F presents with pain in both legs that is induced by walking and is relieved by rest. She had cardiac bypass surgery six months ago and continues to smoke heavily.

A

Peripheral vascular disease (intermittent claudication), Leriche’s syndrome (aortoiliac occlusive disease),
Lumbar spinal stenosis (pseudoclaudication),
Osteoarthritis
W/U: Ankle-brachial index, Doppler U/S—lower extremity, Angiography, MRI—lumbar spine

136
Q

60 yo M presents with dull epigastric pain that radiates to the back, together with weight loss, dark urine, and clay-colored stool. He is a heavy drinker and smoker.

A
Pancreatic cancer 
Acute viral hepatitis 
Chronic pancreatitis 
Cholecystitis/choledocholithiasis 
Abdominal aortic aneurysm 
Peptic ulcer disease 
W/U: Rectal exam, CBC, electrolytes, Amylase and lipase AST/ALT/bilirubin/alkaline phosphatase, U/S—abdomen, CT—abdomen
137
Q

60 yo M presents with nocturia, urgency, weak stream, and terminal dribbling. He denies any weight loss, fatigue, or bone pain. He has had two episodes of urinary retention that required catheterization.

A
Benign prostatic hyperplasia (BPH) 
Prostate cancer 
UTI 
Bladder stones 
W/U: Rectal exam, UA, CBC, BUN/Cr, PSA, U/S—prostate (transrectal)
138
Q

60 yo M presents with sudden onset of substernal heavy chest pain that has lasted for 30 minutes and radiates to the left arm. The pain is accompanied by dyspnea, diaphoresis, and nausea. He has a history of hypertension, hyperlipidemia, and smoking.

A
Myocardial infarction (MI) 
GERD 
Angina 
Costochondritis 
Aortic dissection 
Pericarditis 
Pulmonary embolism 
Pneumothorax 
W/U: ECG, CPK-MB, troponin, CXR, CBC, electrolytes, Echocardiography, Cardiac catheterization
139
Q

61 yo obese F presents with profuse vaginal bleeding over the past month. Her last menstrual period was 10 years ago. She has a history of hypertension and diabetes mellitus. She is nulliparous.

A
Endometrial cancer 
Cervical cancer 
Atrophic endometrium 
Endometrial hyperplasia 
Endometrial polyps 
Atrophic vaginitis 
W/U: Pelvic exam, Pap smear, Endometrial biopsy, U/S—pelvis, Endometrial curettage, Colposcopy, Hysteroscopy
140
Q

65 yo F presents with inability to use her left leg and bear weight on it after tripping on a carpet. Onset of menopause was 20 years ago, and she did not receive HRT or calcium supplements. Her left leg is externally rotated, shortened, and adducted, and there is tenderness in her left groin.

A

Hip fracture
Hip dislocation
Pelvic fracture
W/U: XR—hip/pelvis, CT or MRI—hip, CBC, Serum calcium and vitamin D, Bone density scan (DEXA)

141
Q

65 yo F presents with severe, intermittent right temporal headache, fever, blurred vision in her right eye, and pain in her jaw when chewing.

A
Temporal arteritis (giant cell arteritis) 
Migraine 
Cluster headache 
Tension headache 
Meningitis 
Carotid artery dissection 
Pseudotumor cerebri 
Trigeminal neuralgia 
Intracranial neoplasm
W/U: CBC, ESR, CRP, Temporal artery biopsy, Doppler U/S—carotid, MRI—brain
142
Q

65 yo M presents after falling and losing consciousness for a few seconds. He had no warning prior to passing out but recently had palpitations. His past history includes coronary artery bypass grafting (CABG).

A
Cardiac arrhythmia (causing syncope)
Severe aortic stenosis 
Syncope (other causes) 
Seizure 
Pulmonary embolism 
W/U: ECG, Holter monitoring, CBC, electrolytes, Glucose, Echocardiography, CT—head
143
Q

65 yo M presents with pain in the heel of the right foot that is most notable with his first few steps and then improves as he continues walking. He has no known trauma.

A

Plantar fasciitis
Heel fracture
Splinter/foreign body
W/U: XR—heel, Bone scan

144
Q

65 yo M presents with painless hematuria. He is a heavy smoker and works as a painter.

A
Bladder cancer 
Renal cell carcinoma 
Nephrolithiasis 
Acute glomerulonephritis 
Prostate cancer 
Coagulation disorder (i.e., factor VIII antibodies) 
Polycystic kidney disease 
Genitourinary exam 
W/U: UA, urine cytology, BUN/Cr, PSA, CBC, PT/PTT, Cystoscopy, U/S—renal/bladder, CT—abdomen/pelvis, IVP
145
Q

65 yo M presents with postural dizziness and unsteadiness. He has hypertension and was started on hydrochlorothiazide two days ago.

A
Drug-induced orthostatic hypotension
Vestibular neuronitis 
Labyrinthitis 
Benign positional vertigo 
Brain stem or cerebellar tumor 
Acute renal failure 
W/U: Orthostatic vital signs, CBC, Electrolytes, BUN/Cr, MRI—brain
146
Q

65 yo M presents with right foot pain. He has been training for a marathon.

A

Stress fracture
Plantar fasciitis
Foot sprain or strain
W/U: XR—foot, Bone scan—foot, MRI—foot

147
Q

65 yo M presents with worsening cough over the past six months together with hemoptysis, dyspnea, weakness, and weight loss. He is a heavy smoker.

A
Lung cancer 
Tuberculosis 
Lung abscess 
COPD 
Vasculitis (i.e., Wegener's) 
Interstitial lung disease 
CHF 
W/U: CBC, Sputum Gram stain, culture, and cytology, CXR, CT—chest, PPD, Bronchoscopy
148
Q

67 yo M presents with alternating diarrhea and constipation, decreased stool caliber, and blood in the stool for the past eight months. He also reports unintentional weight loss. He is on a low-fi ber diet and has a family history of colon cancer.

A

Colorectal cancer
Irritable bowel syndrome
Diverticulosis
GI parasitic infection (ascariasis, giardiasis)
Inflammatory bowel disease
Angiodysplasia
W/U: Rectal exam, CBC, AST/ALT/bilirubin/alkaline phosphatase, Colonoscopy, Barium enema, CT—abdomen/pelvis

149
Q

67 yo M presents with blood in his stool, weight loss, and constipation. He has a family history of colon cancer.

A
Colorectal cancer 
Anal fissure 
Hemorrhoids 
Diverticulosis 
Ischemic bowel disease 
Angiodysplasia 
Upper GI bleeding 
Inflammatory bowel disease 
W/U: Rectal exam, CBC, PT/PTT, AST/ALT/bilirubin/alkaline phosphatase, CEA, Colonoscopy, CT—abdomen/pelvis, Barium enema
150
Q

68 yo M presents following a 20-minute episode of slurred speech, right facial drooping and numbness, and right hand weakness. His symptoms had totally resolved by the time he got to the ER. He has a history of hypertension, diabetes mellitus, and heavy smoking.

A
Transient ischemic attack (TIA) 
Hypoglycemia 
Seizure 
Stroke 
Facial nerve palsy 
W/U: CBC, Glucose, Electrolytes, ECG, CT—head, MRI—brain, Doppler U/S—carotid, Echocardiography, EEG
151
Q

68 yo M presents with a two-month history of crying spells, excessive sleep, poor hygiene, and a 7-kg weight loss, all following his wife’s death. He cannot enjoy time with his grandchildren and reluctantly admits to thinking he has seen his dead wife in line at the supermarket or standing in the kitchen making dinner.

A

Normal bereavement
Adjustment disorder with depressed mood
Major depressive disorder with psychotic features
Schizoaffective disorder
Depressive disorder not otherwise specified (NOS)
W/U: Physical exam, Mental status exam, TSH, CBC, Urine toxicology

152
Q

68 yo M presents with LLQ abdominal pain, fever, and chills for the past three days. He also reports recent onset of alternating diarrhea and constipation. He consumes a low-fi ber, high-fat diet.

A
Diverticulitis 
Crohn's disease 
Ulcerative colitis 
Gastroenteritis 
Abscess 
W/U: Rectal exam, CBC, electrolytes, CXR, AXR, CT—abdomen
153
Q

68 yo M presents with slurred speech, right facial drooping and numbness, and right hand weakness. Babinski’s sign is present on the right. He has a history of hypertension, diabetes mellitus, and heavy smoking.

A
Stroke 
TIA 
Seizure 
Intracranial neoplasm 
Subdural or epidural hematoma 
W/U: CBC, electrolytes, PT/PTT, CT—head, MRI—brain (preferred,) Doppler U/S—carotid, Echocardiography
154
Q

70 yo diabetic M presents with episodes of palpitations and diaphoresis. He is on insulin.

A
Hypoglycemia 
Cardiac arrhythmias 
Angina 
Hyperthyroidism 
Hyperventilation episodes 
Panic attacks 
Pheochromocytoma Carcinoid 
W/U: Glucose, CBC, electrolytes, TSH, BUN/Cr, ECG, Holter monitor
155
Q

70 yo F presents with acute onset of severe, crampy abdominal pain. She recently vomited and had a massive dark bowel movement. She has a history of CHF and atrial fi brillation, for which she has received digitalis. Her pain is out of proportion to the exam.

A
Mesenteric ischemia/infarction 
Diverticulitis 
Peptic ulcer disease 
Gastroenteritis 
Acute pancreatitis 
Cholecystitis/choledocholithiasis 
MI 
W/U: Rectal exam, CBC, amylase, lipase, lactate, ECG, CPK-MB, troponin, AXR, CT—abdomen, Mesenteric angiography, Barium enema
156
Q

70 yo F presents with acute onset of shortness of breath at rest and pleuritic chest pain. She also presents with tachycardia, hypotension, tachypnea, and mild fever. She is recovering from hip replacement surgery.

A
Pulmonary embolism 
Pneumonia 
Costochondritis 
MI 
CHF 
Aortic dissection 
W/U: ECG, CXR, ABG, CPK-MB, troponin, CBC, electrolytes, CT—chest with IV contrast, Doppler U/S—legs, D-dimer
157
Q

70 yo insulin-dependent diabetic M presents with episodes of confusion, dizziness, palpitation, diaphoresis, and weakness.

A
Hypoglycemia 
Transient ischemic attack 
Arrhythmia 
Delirium 
Angina 
W/U: Glucos,e CBC, electrolytes, Echocardiography, ECG MRI—brain, Doppler U/S—carotid
158
Q

71 yo M presents with nocturia, urgency, weak stream, terminal dribbling, hematuria, and lower back pain over the past four months. He has also experienced weight loss and fatigue.

A
Prostate cancer 
BPH 
Renal cell carcinoma 
UTI 
Bladder stones 
W/U: Rectal exam, UA, CBC, BUN/Cr, PSA, U/S—prostate (transrectal), CT—pelvis, IVP
159
Q

72 yo M presents with memory loss, gait disturbance, and urinary incontinence for the past six months.

A
Normal pressure hydrocephalus 
Alzheimer's disease 
Vascular dementia 
Chronic subdural hematoma 
Intracranial neoplasm 
Depression 
B12 deficiency 
Neurosyphilis 
Hypothyroidism 
W/U: CT—head, LP—opening pressure and CSF analysis, Serum B12, VDRL/RPR, TSH
160
Q

75 yo M presents with dysphagia that started with solids and progressed to liquids. He is an alcoholic and a heavy smoker. He has had an unintentional weight loss of 7 kg over the past four months.

A
Esophageal cancer 
Achalasia 
Esophagitis 
Systemic sclerosis 
Esophageal stricture 
Amyotrophic lateral sclerosis 
W/U: CBC, CXR, Endoscopy with biopsy, Barium swallow, CT—chest
161
Q

81 yo M presents with progressive confusion over the past several years together with forgetfulness and clumsiness. He has a history of hypertension, diabetes mellitus, and two strokes with residual left hemiparesis. His mental status has clearly worsened after each stroke (stepwise decline in cognitive function).

A
Vascular ("multi-infarct") dementia 
Alzheimer's disease 
Normal pressure hydrocephalus 
Chronic subdural hematoma 
Intracranial tumor 
Depression 
B12 deficiency 
Neurosyphilis 
Hypothyroidism 
W/U: CBC, VDRL/RPR, Serum B12, TSH, MRI—brain, CT—head, LP—CSF analysis (rare)
162
Q

84 yo F brought by her son c/o forgetfulness (e.g., forgets phone numbers, loses her way back home) along with diffi culty performing some of her daily activities (e.g., bathing, dressing, managing money, using the phone). The problem has gradually progressed over the past few years.

A
Alzheimer's disease 
Vascular dementia
Depression 
Hypothyroidism 
Chronic subdural hematoma 
Normal pressure hydrocephalus 
Intracranial neoplasm 
B12 deficiency 
Neurosyphilis 
W/U: CBC, VDRL/RPR, Serum B12, TSH, MRI—brain (preferred), CT—head, LP—CSF analysis (rare)