Step 2 CS Flashcards
48yo F epigastric pain: DD and workup
- PUD
- Cholecystitis
- Gastritis
- Functional or nonulcer dyspepsia
- Perforated ulcer
- Gastric CA
PUD
Rectal exam, occult blood (PUD)
Upper endoscopy (PUD, Gastric CA, Perforation)
Acute Chole
AST/ALT/Bili/Alk Phos/Lipase (Acute chole)
U/S Abd (acute chole)
HIDA (acute chole)
Gastritis
H.Pylori antibody testing (gastritis)
21yo F RLQ pain: DD and workup
- PID
- Appendicitis
- Ruptured ectopic
- Ruptured ovarian cyst
- Adnexal torsion
- Gastroenteritis
- Abortion
- Endometriosis
Appi
- Rectal exam (Appi)
- CBC (Api)
PID
- Pelvic exam (PID)
- Cervical cultures (PID)
Ectopic
- Urine HCG (ectopic)
- U/S abd/pelvis (GI/GU)
- CT abd/pelvis (GI/GU)
- Laparoscopy (GI/GU)
UTI
5. UA (UTI)
21yo F RLQ pain: PE
Appi
- psoas
- obturator
- rovsing’s
UTI/Pyleo
-CVA tenderness
74yo M with pain in R arm: DD and workup
- humeral fracture
- osteoporosis
- shoulder dislocation
- elder abuse
- rotator cuff tear
Humeral fracture/shoulder dislocation
1. XR: R shoulder/arm AP and lateral
Rotator Cuff tear
2. MRI: shoulder
Osteoporosis
3. DEXA bone scan
21yo M with sore throat: DD and workup
- infectious mononucleosis
- acute HIV infection
- viral pharyngitis
- bacterial pharyngitis
Infectious Mononucleosis
- CBC
- Peripheral Smear
- Monospot
- Anti-EBV antibodies
Bacterial/Viral Pharyngitis
- Rapid streptococcal antigen
- Throat culture
Acute HIV infection
7. HIV antibody and viral load
55yo M with blood in stool: DD and workup
- Colorectal CA
- Hemorrhoids
- Diverticulosis
- Angiodysplasia
- Pseudomembranous Colitis (C. Diff)
- Other infectious colitis
- UC
Colorectal CA
- Rectal exam (occult blood)
- CBC
- Colonoscopy
- Flexible proctosigmoidoscopy
Hemorrhoids
5. Anoscopy
Diverticulosis
- CT abd/pelvis
- Double-contrast (air contrast) barium enema
Infection/Inflammatory Bowel Disease
- Stool for C. Difficile toxin
- Fecal leukocytes
46yo M with chest pain: DD and workup
- Myocardial ischemia or infarction
- Cocaine-induced myocardial ischemia
- GERD
- Aortic Dissection
- Pericarditis
- Pneumothorax
- Pulmonary embolism
- Costochondritis
Myocardial Ischemia
- EKG
- Cardiac enzymes (CPK, CPK-MB, troponin)
- Transthoracic echo (TTE)
- Cardiac catheterization
- Cholesterol panel
Aortic Dissection
- CXR
- Transesophageal echo (TEE)
- CT chest with IV contrast
GERD
8. upper endoscopy
7mo M with 1day h/o fever 101F, runny nose, sick contact brother UTI 1 week ago, attends daycare
DD and workup
- Viral URI
- PNA
- Meningitis
- UTI
- Otitis Media
- Gastroenteritis
- Occult bacteremia
Otitis Media
- Pneumatoci otoscopy
- Tympanometry
Occult Bacteremia
3. CBC with Diff, blood culture
UTI
- UA and urine culture
- Renal U/S
- Voiding cysturethrogram
Meningitis
- LP with CSF analysis
- CT Head
PNA
- CXR
- Bronchoscopy
Viral URI
8. Serum antibody titers
18mo F with 2day h/o fever, pulling R ear, difficulty swallowing, maculopapular facial rash spread to trunk, daycare.
DD and workup
- otitis media
- meningococcal meningitis
- Scarlet fever
- fifth disease or other viral exanthem
- varicella
Otitis Media
- Pneumatic Otoscopy
- Tympanometry
Meningitis
- LP with CSF analysis
- Platelets, PT/PTT, D-dimer, fibrin split products, fibrinogen
- CBC with diff, blood culture, UA and Urine Culture
Scarlet Fever
6. Throat culture
Fifth Disase
7. Parvovirus B19 IgM antibody
Varicella
- Skin Scrapings
- Varicella antibody titer
26yo M presents with 1 week h/o cough, fever, runny nose, sore throat. Extensive sexual history. Productive cough. Stabbing pleuritic pain in R chest. On PE tactile fremitus and decreased breath sounds on R side.
DD and workup
- URI associated cough
- Acute bronchitis
- Pneumonia
- Pleurodynia
- Aspiration
- CXR
- CBC
- Sputum gram stain and culture
- Urine Leginonella antigen, serum Mycoplasma PCR, cold agglutinin measurement
- Bronchoscopy with bronchoalveolar lavage
- Pulse oximetry or ABG
- HIV antibody
54yo F with PMH chronic bronchitis 2/2 smoking history presents with 1mo h/o productive cough with blood streaks, weight loss, exposed to TB at work.
DD and workup
- Pulmonary TB
- lung CA
- Lung abscess
- Atypical PNA
- Typical PNA
- COPD exacerbation
- Wegener’s granulomatosis
- CBC
- C-ANCA
- Blood cultures
- PPD
- Sputum: gram stain, AFB smear, routine cultures, mycobacterial cultures, cytology
- CXR: PA and lateral
- CT chest
- Bronchoscopy
- Lung biopsy
52yo F with 3wk h/o jaundice, light stools, dark urine, RUQ pain dull intermittent.
DD and workup
- Extrahepatic biliary obstruction
- Pancreatic CA
- Choledocholithiasis
- Chonangiocarcinoma
- Carcinoma of the ampulla
- sphincter of oddi dysfunction - Viral hepatitis
- Acetaminophen liver toxicity
- Alcohol hepatitis
- Primary Biliary Cirrhosis
- AST/ALT/bilirubin/alk phos
- CBC (chronic liver dx –> splenomegaly –> low platelets)
- PT/PTT (coagulopathy 2/2 liver failure)
- Viral hepatitis serologies
- Acetaminophen level
- Abd U/S
- Abd CT
- MRCP/ERCP
Neurological Exam
- Mini-mental status exam
- CNs 2-12: visual acuity, H test, facial sensation + motor, auditory, “ahhh”, twist head, tongue protrusion
- Motor exam
- Sensory Exam: sensation, sterognosis, graphesthesia, 2 point discrimination
- DTRs
- Gait: tandem, walk on heels and toes
- Cerebellum: finger-nose, heel-shin, rapid hand mvmts
- Romberg sign
Mini-mental status exam (folstein)
- Orientation to time, place
- Name 3 objects, ask patient to repeat all 3
- Serial 7’s from 100 to 5, spell WORLD backwards
- Ask to recall 3 objects from before
- Name objects: pencil, watch, phone
- Repeat “no ifs, and or buts”
- Follow 3 step command: put paper in R hand.. etc.
- Obey the following: CLOSE EYES
- Write a sentence
- Copy a design
65yo F with 1yr h/o difficulty remembering after death of husband, progressively worse. Problems with daily activities, frequent falls, weakness in LUE 2/2 stroke
DD and workup
- Alzheimer’s Disease
- Vascular dementia
- Depression
- Hypothyroidism
- Vitamin B12 deficiency
- Subdural hematoma
- CBC (Vit B12 def macrocytic anemia)
- Electrolytes, Calcium, glucose, BUN/Cr (metabolic probs can cause cognitive dysfunction)
- Serum B12, TSH, RPR (reversible causes)
- CT head or MRI brain (mass, hematoma, stroke, normal pressure hydrocephalus)
- EEG
56yo M PMH DM last 25yrs presents with episodes of palpatations and diaphoresis after missing meals, inability to maintain erection, loss of sensation in stocking-like distribution
DD and workup
- Insulin-induced hypoglycemia
- Peripheral neuropathy: diabetic or alcoholic
- Multiple myeloma
- Diabetic autonomic neuropathy, vascular disease or med-induced ED
Diabetes
- Serum glucose, HbA1c
- UA, urine microalbumin, BUN/Cr
- Nerve conduction studies
Erectile dysfunction
- Genital Exam
- Doppler U/S penis
Multiple Myeloma
4. CBC, SPEP
53yo M with intermittent dizziness last 2 days. Room spinning around him. Episodes last 20mins, progressively worse. Hearing loss in L ear started yesterday. +N/V
DD and Workup
- Meniere’s disease (episodic vertigo, low-freq hearing loss, tinnitus, aural fullness. Caused by syphilis and head trauma)
- Orthostatis hypotension 2/2 dehydration (diarrhea and loop diuretic use)
- Benign Paroxysmal Positional Vertigo (transient vertigo with changes in head movement, no hearing loss)
- Labyrinthitis (2/2 viral infection, hearing loss, tinnitus, virtigo continuous lasts days-week)
- Perilymphatic fistula (hearing loss 2/2 trauma, virtigo lasts seconds)
- Acoustic Neuroma
- Dix-Hallpike maneuver (BPPV)
- VDRL/PRP (r/o syphilus –> Meniere’s disease)
- Audiometry (hearing function)
- MRI brain (central vestibular lesions)
- Brain stem auditory evoked potentials (help dx central vestibular disease)
- electronystagmography
Depression Screening
SIG EM CAPS Sleep Interest Guilt Energy Mood Concentration Appetite Psychomotor agitation/retardation Suicidal Ideation
46yo M c/o fatigue last 3 months started after unsuccessful attempt to save friend after car accident, multiple past sexual partners
DD and workup
- Depression SIG EM CAPS
- Adjustment d/o with depressed mood
- hypothyroidism
- OSA
- PTSD
- HIV infection (h/o STDs)
- CBC (r/o anemia)
- TSH (r/o hypothyroidism)
- Ambulatory nocturnal oximetry (r/o OSA)
- polysomnography (Dx OSA)
- HIV antibody (r/o HIV infection)
- MRI brain (intracranial mass)
32yo F c/o fatigue and weakness for 5mo, increases during the day, domestic abuse by husband, reports polyuria/polydypsia/nocturia.
DD and workup
- Domestic Violence
- Depression
- DM
- Diabetes insipidus
- Anemia
- Myasthenia Gravis
- Hypothyroidism
Anemia
1. CBC, iron level, TIBC, ferritin, serum B12 (investigate anemia)
Diabetes Mellitus
- UA
- Serum glucose, HbA1c
Hypothyroidism
5. TSH
Central DI
- Electrolytes (hypernatremia)
- MRI brain (mass lesions in central DI)
- DDAVP nasal spray test “vasopressin challenge test”
61yo M c/o fatigue and weakness for 6mo. Weight loss, nausea, epigastric pain radiates to back, feels sad, lost interest, drinks alcohol
DD and workup
- Depression, SIG EM CAPS
- Pancreatic CA: weight loss, epigastric pain to rads to back, depression may be an early finding
- Chronic pancreatitis: alcohol use
- PUD: epigastric pain (h/e wt loss unusual)
- Hypothyroidism: fatigue, weakness
- CBC, stool for occult blood: blood loss 2/2 PUD
- Glucose: screen for DM 2/2 pancreatic dysfunction
- Amylase, lipase
- AST/ALT/Bili/Alk Phos
- TSH
- Abd XR: pancreatic calcification
- Abd CT: pancreatic CA
- Upper endoscopy: PUD
35yo F with headaches 2-3x/day for 2 weeks, last 1-2hrs, pounding, right hemisphere, worse with stress and light, alleviated with darkness.
DD and workup
- Migraine: POUND criteria
- Tension HA
- Depression
- Pseudotumor cerebri
- Intracranial mass lesion
- Cluster HA
- Sinusitis
- CBC: look for leukocytosis
- CT head or MRI brain: severe acute HA, chronic unexplained HA or positive neurological exam.
- LP: opening pressure in pseudotumor cerebri
- CT sinus: sinusitis
migraine criteria
POUND Pulsatile One day duration Unilateral Nausea/Vomiting Disabling in intensity
57yo M presents to the ER with bloody urine, CVA tenderness R, polyuria, straining, nocturia, weak stream, dribbling
DD and workup
- Bladder CA: cigarette smoking
- Urolithiasis: sudden severe colicky pain
- Benign Prostatic Hypertension: usually hematuria is microscopic
- Prostate CA
- Renal cell CA: hematuria, flank pain, palpable mass
- Glomerulonephritis
- UTI: hematuria, unusual in males
- Genital exam
- rectal exam
- UA: RBC casts = glomerular dx
- Urine Cx r/o UTI
- Urine cytology
- BUN/Cr
- PSA
- Renal U/S
- Cystoscopy
- CT abd/pelvis
- IVP
differential diagnosis of hematuria:
HITTERS Hematologic or coagulation d/o Infection Trauma Tumor Exercise Renal d/o Stones
clots = bleeding from lower urinary tract
gross blood = malignancy
54yo M with HTN f/u started on HCTZ and propronolol, presents with ED and decreased libido
DD and workup
- Drug induced erectile-dysfunction (antihypertensives, alcohol, Beta-blockers also decrease libido)
- Hypogonadism (low testosterone 2/2 age)
- ED caused by vascular disease (A/W angina, PVD, diminished pulses, hair loss on legs).
- Depression (psychogenic causes can decrease libido and erections)
- Alcohol-related ED
- Peyronie’s Disease: fibrous plaque of tunica albuginea can cause penile scarring and ED
- Genital Exam r/o peyrione’s dx
- Rectal exam r/o prostate dx or masses
- Serum glucose r/o DM causing ED
- Testosterone r/o hypogonadism
- LH/FSH r/o hypogonadism
- Prolactin, TSH r/o pituitary abnormalities
- Ferritin r/o hemochromatosis
- MRI brain r/o pitutary lesion
- Doppler U/S Penis assess blood flow
- Dynamic cavernosography
- BUN/Cr, electrolytes, cholesterol, UA, EKG: long term care of HTN and HLD
33yo F with 2day h/o knee pain, no trauma, h/o fatigue and painful wrists and fingers, morning stiffness last 6mo, oral ulcers, raynaud’s, weight loss.
DD and workup
- Gout
- Pseudogout
- SLE
- RA
- Gonococcal septic arthritis
- Nongonococcal septic arthritis
- Osteoarthritis
- Pelvic exam and cultures (Gonococcal septic arthritis)
- Knee aspiration and synovial fluid analysis (r/o septic arthritis, gout, pseudogout)
- XR knee and hands (r/o RA, gout, pseudogout, OA)
- CBC (low in SLE, leukocytosis in gout + septic arthritis)
- ANA, anti-dsDNA, RF (SLE, RA)
- Blood culture (septic arthritis)
66yo M presents with R hand tremor occurs at rest, worse with fatigue, bradykinesia, muscle rigiditiy
DD and workup
- Parkinson’s Disease (resting tremor 6Hz freq, rigidity, bradykinesia, postural instability)
- Essential Tremor (worse when hand stretched out or action tremor worse at end of movement FTN)
- Physiologic tremor (10hz, worse with meds, anxiety, excitement, caffeine)
- midbrain lesion (2/2 trauma, stroke, demyelination)
- Drug-induced tremor (BB, nicotine, TCAs, steroids)
- Psychogenic tremor
- Wilson’s disease (resting tremor
- Hypterthyroidism
- TSH: screen for hyperthyroidism
- Heavy metal screen: mercury, arsenic toxicity
- MRI brain (midbrain, BG)
- Ceruloplasmin, slit lamp, AST/ALT, CBC, 24-hr urinary copper, liver biopsy
49yo M presents with syncope a few hours ago, suddently felt light headed, palpatations, LOC, fell. Unconcious with shaking for 30sec. No confusion or neurological defects following.
DD and Workup
- Convulsive syncope (seizure-like activity after syncope, no seizure workup required)
- Vasovagal syncope (preceded by N/sweating/tachy/feeling faint, postmicturition syncope)
- Cardiac arrhythmia: EKG, Holter monitor, ECHO
- Drug-induced orthostatic hypotension
- Seizure: EEG, MRI
- Aortic Stenosis: ECHO
Workup
- CBC, electrolytes: r/o anemia, electrolyte imb
- CXR r/o lung mass or cardiomyopathy
- CT head r/o brain mass/hemorrhage or MRI brain for focal deficits
- EKG, Holter r/o arrhythmia
- ECHO r/o aortic stenosis or atrial myxoma
- Prolactin elevated 1hr following gen seizure
- EEG r/o seizure activity
30yo F with PMH Bipolar d/o treated with lithium presents with 20lb weight gain over 3months. Recently stopped smoking. Dry skin, cold intol.
DD and workup
- Smoking cessation (gain 5lbs)
- Hypothyroidism: TSH
- Lithium-related obesity (wt gain S/E)
- Familial obesity: screen for comp (Glu, HLD, TG)
- Pregnancy (urine hCG)
- Cushing’s syn (dexamethasone suppression test, 24-hr urine free cortisol)
- TSH (hypothyroidism)
- urine hCG (pregnancy)
- Glucose, cholesterol, TG (complications of obesity)
- Dexamethasone supp test (cushing)
- 24hr urine free cortisol (cushing)
36yo F with amenorrhea for 3mo, milky d/c from breast, abnormal facial hair, weight gain.
DD and workup
- Pregnancy: urine hCG
- Hyperprolactinoma: prolactin, MRI brain
- PCOS: LH/FSH, testosterone, DHEAS, exam
- Thyroid disease: hyper or hypo TSH
- Premature ovarian failure: LH/FSH
- Asherman’s syndrome
- Pelvic/breast exam: visualization
- Urine hCG: preg
- LH/FSH: PCOS
- Prolactin/TSH: thyroid and hyperprolactinemia
- Electrolytes, glucose,BUN/Cr, ALT/Bili/Alk Phos: renal and hepatic function, hypercortisolism
- Testosterone, DHEAS: hyperandrogenism 2/2 PCOS or ovarian/adrenal tumors
- MRI brain: pituitary
- Hysteroscopy: Asherman’s
28yo F presents with dysparunia superficially and with deep thrusting, white d/c, fishy odor, vaginal pruritus.
DD and Workup
- Vulvovaginitis: pelvic exam, wet mount, KOH prep, “whiff” test
- Cervicitis: cervical cultures
- Endometrosis: laparoscopy
- Vulvodynia
- Domestic violence
- Pelvic tumor: Pelvic CT
- Vaginismus: fear of intercourse
- Pelvic exam
- Wet mount, KOH prep, “whiff” test (BV “fishy odor” after KOH, candida hyphae, trichomonas motile)
- Cervical cultures
- Imaging r/o masses
- Laparoscopy: gold standard for endometriosis dx
51yo construction worker c/o lower back pain s/p lifting heavy boxes 1 wk ago. Pain is 8/10 sharp and radiates to L thigh and foot. Worse w/ movement. Difficulty urinating and incomplete emptying of bladder 6mo ago.
DD and workup
- Disk herniation
- Lumbar muscle strain
- Degenerative arthritis
- Lumbar spinal stenosis
- Metastatic prostate CA
- Multiple myeloma
- Malingering
- Rectal exam: saddle anesthesia, prostate mass, sphincter tone
- XR lumbar spine: degeneration, masses, stenosis
- MRI lumbar spine: herniation
- PSA: prostate CA
- CBC, Ca, BUN/CR: multiple myeloma
- serum and urine protein electrophoresis: MM
6mo F with 1day h/o diarrhea, weakness, drowsiness, fever 100.5, 6 watery BM/day, no blood, no urination.
DD and workup
- Rotavirus: causes 60% of acute ped infectious diarrhea
- Bacterial diarrhea: Shigella, Salmonella, Campylobacter, Yersinia
- Malabsorption: milk intolerance, too young for juice
- UTI or pyelonephritis: diarrhea can be a response
- Intissusseption: Abd pain, vomiting, bloody stools
- Bacteremia: fever, drowsiness, no UOP
- Rotavirus enzyme immunoassay
- Electrolytes
- Stool leukocytes, Culture, Ova and parasitology, pH
- UA
- Abd XRay
- Blood Cx
A 75yo M presents with bilateral hearing loss 1 yo progressively worsening. No ear pain, discharge, vertigo, LOB or trauma.
DD and workup
- Presbycusis = age related hearing loss
- Cochlear nerve damage due to loud noise
- Otosclerosis = elderly, conductive hearing loss
- Meniere’s disease (2/2 trauma, syphilis)
- Ototoxicity (asprin, ABX)
- Acoustic neuroma
- Audiometry (assess hearing)
- Tympanography (conduction of sound in middle ear)
- Brain stem auditory evoked potentials
- CT head r/o intracranial process, bleed
- VDRL/RPR r/o syphilis a/w meneire’s dx
8yo M continuing to wet the bed, never had continence, no dysuria, hematuria, fever or urgency. No abd pain or constipation. No recent stress in family.
DD and workup
- Monosymptomatic primary nocturnal enuresis
- Secondary enuresis
- UTI
- Constipation (may put pressure on bladder)
- Sleep apnea (enuresis a/w sleep apnea + narcolepsy)
- Functional bladder disorder
- Genital exam (examine genitals for abnormalities)
- UA
- Urine culture
- First-morning urine specific gravity (indicates if ADH released)
- Renal U/S (look for structural abnormalities)
- BUN/Cr to evaluate renal function
25yo M presents hours after MVA with L chest pain, LUQ pain, L pleuritic pain with decreased breath sounds, recent diagnosis of infectious mononucleosis. Reports dyspnea and productive cough with low grade fever.
DD and workup
- Pneumothorax = trauma, dyspnea
- Hemothroax = trauma, dyspnea
- Pneumonia = resp distress, cough, fever
- Rib fracture = L chest pain and pleuritic pain
- Splenic rupture 2/2 mono
- Pleuritis = viral inflammation of pleura
- CXR r/o pneumothorax and hemothroax
- CT abd r/o free air in abd and splenic laceration
- Pulse Oximetry
- Urine toxicology
- Blood alcohol level
- Sputum gram stain and culture (PNA)
25yo F presents to the ED after being sexually assaulted. Presents with SOB and palpitations. R chest pain is non-radiating, exacerbated by movement and deep breaths and relieved by sitting still.
DD and workup
- Rib/bone fracture (2/2 trauma, causes pain on inspiration and cough)
- Pneumothorax/hemathorax: CXR
- STDs: sexual assault victims require Trichomoniasis, chlamydia, gonorrhea, HIV and Hep B
- Pregnancy: all sexual assault victims
- Pelvic exam: evaluate for trauma
- Urine hCG: preg
- Wet mount, KOH prep, cervical culture
- XR skeletal survey: look for broken bones
- HIV antibody, VDRL, HBV antigen
- CXR: pneumothorax, pleural effusions, rib fractures
- Evidence collection using rape kit
” PEARLS”
Partnership, Empathy, Apology, Respect, Legitimization, Support
Partnership: work together with ur patient to identify the main concerns ( let’s deal with this together, …or we can do this…use these type of sentence )
Empathy: acknowledge and show understanding of the patient’s feelings (that sounds hard,…you look upset…)
Apology: take personal responsibility when it is appropriate to do so ( I’m sorry I was late,…or even I’m sorry this happened to you)
Respect: value the patient’s choices, behaviors, and decisions ( you have obviously worked hard on this…)
Legitimization: validates and shows understanding for the patient’s feelings and choices ( Anyone would be confused or sad or upset by this situation )
Support: should be continually offered to the patient ( I’ll be here when you need me…)
28yo G0 presents with positive pregnancy test. FH of diabetes, thyroid problems and obesity.
DD and workup
- Normal pregnancy
- Ectopic pregnancy
- Molar pregnancy
- Breast/pelvic exam
- Urine hCG
- U/S pelvis (intraurterine vs. extrauterine)
- CBC, serum glucose (FH diabetes and anemia)
- TSH (FH thyroid problems).
- RPR, rubella IgG, HBsAg, HIV antibody (prenatal trans)
- Blood type, Rh, antibody screen (Rho antibody)
- Pap smear (r/o cervical dysplasia and CA)
- Cervical GC DNA testing
- UA, urine culture (pregnant women at risk UTIs)
20yo F college student presents with insomnia. Very stressed about about school performance. She drinks 5 cups of coffee/day, has lost weight, sweaty palms.
DD and workup
- Anxiety
- Caffeine-induced insomina
- Hyperthyroidism
- Insomnia due to depression
- Adjustment insomnia 2/2 any significant life event
- Illicit drug use
- OSA
- TSH, free T4 r/o hyperthyroidism
- CBC with diff, chem 8 r/o cancer (wt loss, fatigue)
- Urine toxicology r/o stimulant use
- Polysomnography r/o OSA
- ECG: changes 2/2 hyperthyroid and anxiety d/o
27yo M presents with hearing voices and seeing strange writing on the wall since yesterday. Believes someone may be sending him messages. Admits to illicit drug use 2 days before. Has h/o PCP, MDMA (ecstacy).
DD and workup
- Substance-induced psychosis
- Brief psychotic d/o 2/2 stressful event
- Psychosis 2/2 medical condition
- Narcolepsy: visual hallucinations before falling asleep
- Seizure: visual hallucinations of epileptic origin
- Urine toxicology
- Mental status exam: neurologic d/o
- electrolytes: detect underlying medical condition
- LFT: detect underlying medical condition
- TSH, free T4: detect underlying medical condition
- EEG: seizure activity
- Polysomnogram: narcolepsy
10yo F presents with 1mo diagnosis of DM (unknown type), presented with excessive thirst and urination. Mom comes to the office because she is concerned.
DD and workup
- T1 DM
- T2 DM
- Secondary cause of DM such as Cushing’s
- Basal metabolic profile: serum electrolytes and glucose
- HgA1C
- UA, urine microalbumin
- Insulin and C-peptide levels: can identify T1DM
- Islet cell antibodies: identify T1DM
- 24-hour urine free cortisol (r/o coexisting Cushing’s)
35yo F presents with R calf pain few days duration. Constant pain, aggravated by walking and extending knee. A/w swelling, redness, warmth. Recent 15hr flight. Bandage on skin from recent fall. +Homan’s sign. FH of DVT
DD and workup
- DVT
- Cellulitis
- Rupture of Baker’s cyst
- Hematoma
- Rupture of medial head of gastrocnemius
- spasm due to injury or sprain
- Doppler U/S: DVT
- D-dimer: DVT
- Hypercoagulability testing: underlying condition
- CBC with diff: infection, leukocytosis
- CPK and myoglobin levels: muscle injury
- CT venography: DVT
- MRI: DVT
31yo M presents with pain on plantar surface of R heel, training for a marathon, worse in the morning and after prolonged sitting.
DD and workup
- Plantar Fasciitis
- Calcaneal stress fracture
- Achilles Tendinitis
- Retrocalcaneal Bursitis
- Tarsal tunnel syndrome
- Foreign body
- Ankle sprain
- XR right ankle: check for bone spurs or calcification
- Bone Scan r/o calcaneal stress fracture
- MRI r/o soft tissue involvement
5day old M presents with yellow discoloration of the eyes and skin for 2 days
DD and workup
- Physiologic Jaundice
- ABO or Rh incompatibility
- Neonatal sepsis
- Cephalohematoma
- Breast-FEEDING jaundice
- Polycythemia
- Familial neonatal hyperbilirubinemia
- Total and indirect bilirubin: phototherapy when >15
- Blood typing
- Direct Coombs test
- CRP: infection
- CBC: H/H for hemolysis, infection
- Titers for CMV, toxo, rubella: TORCH infections
DD for 1-2week old infant jaundice (late onset)
DD and workup
- Breast milk jaundice
- Biliary atresia
- Metabolic disorders: hypothyroid, galactosemia, spherocytosis, G6PD
2yo F c/o sudden noisy breathing progressively worse, was playing with toys, consistent sound heard best on inhalation.
DD and workup
- Foreign body aspiration
- Croup: barking cough, 6mo-3yrs
- Laryngitis: hoarse voice, 5+yrs
- Epiglottitis: drooling, better leaning forward, 2-6yo
- Retropharyngeal abscess: muffled, drooling, less than 6yo
- Angioedema: stridor and facial edema
- Peritonsillar abscess: sore throat and tonsillitis, 10+
- Laryngeal papilloma: hoarse voice, 3mo-3yo
- ABG: assess ventilation
- CXR: PA and lateral
- XR neck: AP and lateral (steeple sign, thumbprint sign)
- CBC with diff: r/o infection
- Direct laryngoscopy: laryngomalacia or lesions
- Bronchoscopy: foreign body aspiration
32yo M presents for pre-employment medical exam. Chronic cough for many years, productive white sputum 1/2 tsp. Immigrated from Africa 1 mo ago. Chronic smoker. Past work history of coal miner. Never tested for TB.
DD and workup
- Pulmonary TB (immigrant)
- COPD/chronic bronchitis (smoking history)
- Pulmonary silicosis (h/o coal mining)
- Asthma (can cause chronic cough)
- GERD (can cause chronic cough)
- CXR: PA and lateral: TB, silicosis, cough, asthma
- PPD: TB
- Sputum gram stain, AFB smear, routine and mycobacterial sputum cultures: infection
- CBC: infection
62yo M presents with hoarseness x3mo, weight loss, fatigue, smoking and drinking history, FH hypothyroidism and lung cancer. Flu 1 wk ago.
DD and workup
- Laryngeal cancer (drinking, smoking)
- Vocal cord polyps/nodules (overuse voice)
- Laryngitis (flu, viral infection)
- Hypothyroidism (causes hoarseness, FH)
- Mitral valve stenosis (LAE, compress recurrent laryn n)
- CBC: infection, anemia a/w hypothyroidism
- Laryngoscopy: gold standard for larynx evaluation
- TSH: hypothyroidism
- CT chest/neck: mass growth
- ECHO (MVS)
67yo F presents with 2day h/o neck pain/stiffness and LUE numbness. Happened after quick rotation to the left. Recent weight loss. PMH osteopenia on DEXA.
DD and workup
- disk herniation: radiculopathy
- cervical fracture 2/2 osteopenia
- neck muscle strain
- osteoarthritis: compression of nerves
- cervical spondlosis
- metastatic cancer: wt loss, spinal lesion, metastatic CA
- multiple myelomaL spinal lesions
- C-spine X-ray: radiculopathy
- C-spine MRI:
- Nerve conduction studies: cause of loss of sensation
- CBC, calcium, BUN/Cr: multiple myeloma
- Serum and urine protein electrophoresis
11mo F presents with tonic-clonic seizure, 2 day h/o fever 102.9, decreased PO and UOP, postictal drowsiness
DD and workup
- simple febrile seizures: isolated seizure
- meningitis: kid 102
- LP: meningitis
- CBC, electrolytes: infection, electrolyte ab
- Blood Cx, UA, Urine Cx: septic
- CT head: brain abscess, encephalitis, hemorrhage
- EEG: epileptic activity