Step 2 CK Flashcards

1
Q

(Glipizide, glyburide, glimepiride) What kind of medications are these and what do they do?

A

Insulin medications and they increase endogenous secretion of insulin

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2
Q

How does metformin work?

A

Increases insulin sensitivity

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3
Q

What are the side effects for glyburide, glipizide and glimepriride?

A

Hypoglycemia and weight gain

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4
Q

How does rosiglitazone work?

A

Increase insulin sensitivity

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5
Q

What is the side effect of rosiglitazone?

A

weight gain and edema

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6
Q

How do they alpha glucosidase inhibitors work?

A

decrease intestinal absorption of carbohydrates

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7
Q

Whats the symptomatic treatment for hyperthyroidism?

A

Propanolol

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8
Q

Whats the main treatment for hyperthyroidisim?

A

Methimazole or PTU

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9
Q

Whats the definitive treatment for hyperthyroidism?

A

radioactive thyroid ablation or surgery

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10
Q

How do you treat thyroid storm?

A

IV propanolol and steroids

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11
Q

What kind of thyroid nodules has an increase risk of malignancy?

A

Cold nodules

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12
Q

Does increased uptake or decreased uptake hold an increase risk of malignancy?

A

decreased

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13
Q

What condition gives you persistent serum hypercalcemia, low calcium in urine, and normal PTH and no symptoms?

A

Familial hypocalcuric hypercalcemia

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14
Q

How do you treat hypercalcemia?

A

IV fluids and loop diuretics

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15
Q

Which cushings is suppressed with high dose dexamethasone?

A

Cushing disease

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16
Q

What is the treatment for a Prolactinoma?

A

Dopamine agonist (bromocriptine, cabergoline)

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17
Q

What is the treatment for pheochromocytoma?

A

Alpha blockers and beta blockers

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18
Q

What is the neuroimaging finding for schizophrenia?

A

Enlargement of cerebral ventricles

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19
Q

What is the neuroimaging finding for panic disorder?

A

decreased volume of amygdala

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20
Q

What is the neuroimaging finding for autism?

A

increased total brain volume

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21
Q

What is the neuroimaging finding for obsessive compulsive disorder?

A

abnormalities in orbitofrontal cortex and striatum

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22
Q

What is the neuroimaging finding for post traumatic stress disorder?

A

decreased hippocampal volume

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23
Q

What drug is contraindicated in cocaine induced STEMI?

A

Beta blockers

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24
Q

What is the test of choice for meconium ileus and hirschsprung disease?

A

contrast enema

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25
Q

If a patient has recurrent nephrolithiasis what would be the best advice for prevention of stones?

A

decrease Protein in the diet

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26
Q

What kind of hemangioma do you get in infancy?

A

Strawberry hemangioma (superficial hemangioma)

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27
Q

What is the side effect for methimazole?

A

Agranulocytosis

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28
Q

What is the side effect for PTU?

A

Hepatic failure

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29
Q

What is the side effect for the calcium channel blocker amlodipine?

A

Peripheral edema

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30
Q

How do you treat a scaphoid fracture?

A

immobilization

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31
Q

What is the best test to diagnose stones?

A

CT scan without contrast or ultrasound

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32
Q

What is the side effect for amiodarone?

A

Pulmonary toxicity

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33
Q

What is plummer-vinson-syndrome?

A

Where you have esophageal webs, iron deficiency anemia and glossitis

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34
Q

What is the musculature made out of in the upper 3rd of the esophagus?

A

Skeletal muscle

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35
Q

What is the musculature made out of in the lower 3rd of the esophagus?

A

smooth muscle

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36
Q

If you have painfull swallowing what imaging test would you do? (odonophagia)

A

Endoscopy

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37
Q

If you had difficulty swallowing what imaging test would you do? (dysphagia)

A

Barium swallow then endoscopy

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38
Q

What condition gives you chest pain, dysphagia and odynophagia after ingestion of hot or cold liquids?

A

Esophageal spasm

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39
Q

What is the treatment for esophageal spasm?

A

Nitrates or CCB

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40
Q

What muscle is affected in a Zenker diverticulum?

A

cricopharyngeus muscle

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41
Q

What is the most common type of esophageal cancer worldwide?

A

Squamous cell carcinoma

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42
Q

What is the most common esophageal cancer in the United States?

A

Adenocarcinoma

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43
Q

What is the risk factors for squamous cell carcinoma of the esophagus?

A

Alcohol and smoking

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44
Q

What is the risk factors for adenocarcinoma od the esophagus?

A

Barrets esophagus from Chronic GERD

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45
Q

What is the location in the esophagus where you are most likely to find squamous cell carcinoma?

A

upper and middle 3rds of the esophagus

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46
Q

What is the location in the esophagus where you are most likely to find adenocarcinoma?

A

lower 1/3 of the esophagus

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47
Q

How would you diagnose gastritis?

A

upper endoscopy

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48
Q

What is the triple therapy for H.pylori infection?

A

amoxicillin, clindamycin, omeprazole

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49
Q

What are stress ulcers and how do you treat them?

A

Stress ulcers include curling ulcers from burn injuries and cushing ulcers from traumatic brain injury. Treat with prophylactic PPIs

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50
Q

What is a krunkenberg tumor?

A

It is a gastric adenocarcinoma that metastasizes to the ovary

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51
Q

What is MALT?

A

MALT is mucosa-associated lymphoid tissue lymphoma which is a rare gastric tumor associated with chronic H. pylori infection that can be cured with triple therapy

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52
Q

What cancer is associated with an enlarged left supraclavicular lymph node?

A

Gastric cancer

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53
Q

What is the treatment for diarrhea caused by campylobacter?

A

Erythromycin

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54
Q

What is the most common cause of bacterial diarrhea?

A

campylobacter

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55
Q

What is the most common cause of pediatric diarrhea?

A

rotavirus

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56
Q

Whats the most common complication of C. diff?

A

toxic megacolon

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57
Q

What is the treatment for C.diff

A

metronidazole or vancomycin

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58
Q

What is the treatment for entamoeba histolytica?

A

metronidazole

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59
Q

How do you treat salmonella and shigella?

A

TMP-SMX

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60
Q

What does lactose break down into and what enzyme facilitates this?

A

glucose and galactose facilitated by lactase

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61
Q

What condition present with abdominal cramps, wheezing, cutaneous flushing, diarrhea, and right sided cardiac valvular lesions?

A

Carcinoid syndrome

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62
Q

What is the treatment for carcinoid syndrome?

A

octreotide

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63
Q

How do you diagnose carcinoid syndrome?

A

Urine levels of 5-HIAA

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64
Q

What condition gives you periodic crampy abdominal pain, bilious vomiting, abdominal distention and tenderness, no passing of flatus or stools and hyperactive bowel sounds?

A

Small bowel obstruction

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65
Q

What condition gives you continuous diffuse abdominal pain, nausea and vomiting, abdominal distenstion and tenderness, hypoactive bowel sounds and no flatus or bowel movements?

A

Ileus

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66
Q

What is the most common cause of acute lower GI bleeding in older patients?

A

Diverticulosis

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67
Q

What is Charcot’s triad and what condition is it associated with?

A
  1. RUQ pain
  2. Jaundice
  3. Fever/chills
    Associated with ascending cholangitis
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68
Q

What condition is associated with an increased alkaline phosphatase level and increased direct bilirubin?

A

Choledocolithiasis

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69
Q

What is the next step in management for acute ascending cholangitis and choledocolithiasis?

A

ERCP

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70
Q

What are anti-smooth muscle antibodies associated with?

A

Autoimmune hepatitis

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71
Q

What is the treatment for acute hepatitis?

A

supportive care

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72
Q

What is the treatment for chronic hepatitis B?

A

interferon and lamivudine

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73
Q

What is the treatment for chronic hepatitis C?

A

interferon and ribavirin

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74
Q

What condition is associated with increased alkaline phosphatase, jaundice, pruritus, and positive antimitochondrial antibodies?

A

Primary biliary cirrhosis

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75
Q

What is the treatment for primary biliary cirrhosis?

A

ursodeoxycholic acid

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76
Q

What is the treatment for wilsons disease?

A

penicillamine

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77
Q

What is the hallmark finding in pancreatic cancer?

A

nontender, palpable gallbladder

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78
Q

What is the initial workup for a postmenopausal women with an adnexal mass?

A

transvaginal ultrasound and CA-125 level

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79
Q

What is the treatment for a patient with WPW syndrome who is in atrial fibrillation?

A

Procainamide

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80
Q

What is the test of choice for malrotation/volvulus?

A

upper GI series

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81
Q

What medications can you use to drive potassium intracellularly?

A
  1. Insulin
  2. Glucose
  3. Sodium bicarbonate
  4. Albuterol
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82
Q

What is the treatment for pseudotumor cerebri?

A

Acetazolamide

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83
Q

If you have blood at the beginning of urination what should you think of?

A

urethral injury

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84
Q

If you have blood at the end of urination what should you think of?

A

Bladder or prostate problems

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85
Q

At what weight should an infant not get immunizations?

A
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86
Q

Whats the mutation in Marfans syndrome?

A

Fibrillin 1 gene

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87
Q

What are the treatments for BPH

A

Alpha blockers (terazosin, tamsulosin) or finesteride

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88
Q

What is the treatment for bullous impetigo?

A

Oral antibiotics like clindamycin, cephalexin, dicloxcillian

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89
Q

What is the treatment for non-bullous impetigo?

A

topical muciprocin

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90
Q

What is the problem with giving lidocaine to a person who had a MI?

A

It can increase risk for asystole

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91
Q

What is the treatment for measles?

A

vitamin A and supportive care

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92
Q

What are the complications of bronchiolitis in infants?

A

apnea or respiratory failure

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93
Q

What are the complications of subarachnoid hemorrhage?

A
  1. Rebleeding after day 1
  2. Vasospasm after day 3
  3. increased ICP
  4. Seizures
  5. SiADH
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94
Q

What in the spinal fluid and confirm the diagnosis of subarchnoid hemorrhage?

A

Xanthrochromia

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95
Q

recurrent stones since childhood, hexagonal crystals on urnalysis and positive cyanide nitroprusside test is associated with what condition?

A

Cystinuria

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96
Q

What is the abnormality in cystinuria?

A

Defective amino acid transport

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97
Q

Pagets disease of the breast is associated with what kind of cancer?

A

Adenocarcinoma

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98
Q

What biopsy finding are suggestive of bullous pemphigoid?

A

IgG and C3 deposits at the dermal-epidermal junction

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99
Q

What are the autoantibodies targeting in pemphigus vulgaris?

A

desmoglein

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100
Q

What are the autoantibodies targeting in bullous pemphigoid?

A

hemidesmosomes

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101
Q

Pronator drift is associated with what type of brain abnormality?

A

upper motor neuron disease

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102
Q

Which cause of direct hyperbilirubinemia gives you dark granular pigment in the hepatocytes?

A

Dubin johnson syndrome

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103
Q

Leads 2, 3, AVF correlates with what kind of MI?

A

Inferior MI

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104
Q

Whats the antidote to heparin?

A

Protamine sulfate

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105
Q

What is cryoprecipitate?

A

More concentrated form of fresh frozen plasma. Contains factor 8 and fibrinogen

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106
Q

What is the diagnostic test for vWD?

A

ristocetin cofactor assay

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107
Q

What is the treatment for vWD?

A

DDVAP(desmopressin)

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108
Q

What is the difference between the labs in vWD and hemophilia?

A

In vWD there is platelet dysfunction so the bleeding time and PTT is prolonged but in hemophilia PTT is prolonged

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109
Q

What 3 things can give you microangiopathic hemolytic anemia that leads to schistocyted on peripheral blood smear?

A
  1. HUS
  2. DIC
  3. TTP
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110
Q

What is the treatment for TTP?

A

steroids and plasmapheresis

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111
Q

What is the treatment for ITP?

A

Steroids and IVIG

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112
Q

What is contraindicated in patients with HUS?

A

antibiotics

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113
Q

What are some specific tests for iron deficiency anemia?

A

Increased RDW and low ferritin levels

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114
Q

elevated MMA and elevated homocysteine is associated with what?

A

b12 deficiency

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115
Q

Normal MMA and elevated homocysteine levels are associated with that?

A

folate deficiency

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116
Q

What is indicative of a positive schilling test?

A

When a patient suspected of B12 deficiency is given radiolabed B12 and it comes out in the urine. Tell you there is a B12 deficiency

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117
Q

When you have increased LDH levels and decreased haptoglobin what does that tell you?

A

Hemolysis

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118
Q

The presence of auer rods are indicative of what condition?

A

AML

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119
Q

What is the translocation for the philadelphia chromosome and what condition is it associated with?

A

t(9;22) associated with CML

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120
Q

What is the preferred treatment for the M3 subtype of AML?

A

All trans-retnoic acid therapy

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121
Q

What chromosome translocations are associated with M3 subtype of AML?

A

Chromosome 15 and 17

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122
Q

Smudge cells are associated with what condition?

A

CLL

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123
Q

What is the treatment for CML

A

imtinab

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124
Q

Reed Sternberg cells are associated with what condition?

A

Hodgkins lymphoma

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125
Q

Which type of hodgkins disease has the best prognosis?

A

Lymphocyte predominant

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126
Q

What symptoms should raise suspicion for multiple myeloma?

A

anemia, renal failure and bone pain

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127
Q

Dutcher bodies are characteristic of what disease?

A

Waldenstrom’s macroglobulinemia

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128
Q

What is AL amyloid associated with?

A

multiple myeloma and Waldenstroms macroglobulinemia

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129
Q

What is AA amyloid associated with?

A

chronic inflammatory diseases

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130
Q

What is graft vs host disease?

A

Its a type of allogenic infection where donot T lymphocytes attack host tissues in the skin, liver and GI tract

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131
Q

What is the treatment for graft vs host disease?

A

high dose steroids

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132
Q

Whats the problem in hyperacute transplant rejection?

A

Preformed antibodies ABO incompatability

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133
Q

When would you see a reaction in hyperacute transplant rejection and what would that reaction be?

A

within minutes and vascular thrombi or ischemia

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134
Q

What is the problem in acute transplant rejection?

A

T cell mediated response

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135
Q

What are the side effects of HCTZ diuretic?

A

hyperglycemia, hyperlipidemia, hyperuricemia, hypokalemia, hypomaganesium, hyponatremia

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136
Q

What is bronchoalveolar lavage used for?

A

to evaluate for malignancy or opportunistic infections like PCP

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137
Q

What is the single most important prognostic factor in breast cancer?

A

TNM staging

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138
Q

Does central cord syndrome affect the lower extremeties or the upper extremeties?

A

upper extremeties

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139
Q

What is the treatment of choice for syphillis?

A

Penicillin

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140
Q

What is a patient is allergic to penicillin, what is the treatment for syphillis?

A

doxycycline

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141
Q

What is a patient is pregnant with syphilis and they are allergic to penicillin, what is the treatment?

A

desensitized penicillin

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142
Q

What is a patient has tertiary syphillis and they are allergic to penicillin, what is the treatment?

A

ceftriaxone

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143
Q

Ankylosing spondylitis is associated with what eye condition?

A

ANterior uveitis

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144
Q

What is the treatment for gastroparesis?

A

metoclopromamide

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145
Q

What is the management of suspected spleen injury?

A

If hemodynamically unstable do exploratory laparatomy. If hemodynamically stable do a CT scan and decide if surgery is needed

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146
Q

If you suspect endometriosis what is the best way to test for it?

A

Laparascopy

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147
Q

What is the treatment for Printzmetal angina?

A

Nitrates or CCB

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148
Q

What are the contraindications to rotavirus vaccination?

A
  1. History of intussusception
  2. History of GI abnormalities
  3. Anaphylaxis
  4. SCID
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149
Q

After diagnosing a patient with Guillain-Barre syndrome what is the most important next step in management?

A

Assess pulmonary function with spirometry

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150
Q

What receptors are affected in Lambert Eaton syndrome?

A

Presynpatic voltage gated calcium channels

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151
Q

What receptors are affected in Myasthenia gravis?

A

Postsynaptic acteylcholine receptors

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152
Q

Whats unique about blastomycosis?

A

Endemic in Wisconsin, Mississippi, Ohio. Has pulmonary, skin, and lytic bone lesion findings

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153
Q

What conditio can give you these findings; pericardial calcifications, prominent x and y descents, fatigue and dyspnea and fluid overload?

A

Constrictive pericarditis

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154
Q

Where are the endemic areas for tuberculosis constrictive pericarditis?

A

Africa, India and China

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155
Q

What is the treatment for tinea capitis?

A

Oral Griseofulvin

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156
Q

How do you treat uric acid stones?

A

Alkinaztion of the urine with potassium citrate

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157
Q

What is the management for spontaneous bacterial peritonitis?

A

Diagnostic paracentesis

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158
Q

What are the most likely cultured bacteria in spontaneous bacterial peritonitis?

A

E.coli and Klebsiella

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159
Q

Malabsorption, increased alk phos and PTH, decreased calcium and phosphorus are associatef with what condition?

A

Osteomalacia

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160
Q

What is the problem in osteomalacia?

A

Vitamin D deficiency and impaired osteoid matrix mineralization

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161
Q

What is the treatment for hairy cell leukemia?

A

Cladribine

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162
Q

What kind of gait do you get with parkinson disease?

A

hypokinetic gait

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163
Q

Malabsorption, increased alk phos and PTH, decreased calcium and phosphorus are associatef with what condition?

A

Osteomalacia

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164
Q

What is the problem in osteomalacia?

A

Vitamin D deficiency and impaired osteoid matrix mineralization

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165
Q

What is the treatment for hairy cell leukemia?

A

Cladribine

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166
Q

If i have a patient with increased serum iron, decreased TIBC and normochromic and hypochromic RBCs what condition should i be thinking of?

A

Sideroblastic anemia

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167
Q

What is the treatment for sideroblastic anemia?

A

Pyridoxine

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168
Q

What is the next step in treatment of a patient who is having an acute excerbation of COPD who has been given short acting beta agonists, steroids and antibiotics and still isnt responding to treatment?

A

Noninvasive positive pressure ventilation

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169
Q

What is the treatment for stable angina?

A
  1. Beta blockers
  2. CCB
  3. Nitrates
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170
Q

Menniers Disease affects which part of the ear?

A

Inner ear

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171
Q

What is the treatment for SVT?

A

Adenosine

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172
Q

What is the treatment for Ventricular tachycardia?

A

Amiodarone or lidocaine

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173
Q

What are the metabolic abnormalities in tumor lysis syndrome?

A
  1. Hyperuricemia
  2. Hyperkalemia
  3. Hyperphosphatemia
  4. Hypocalcemia
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174
Q

What is the most common cause of pneumonia from 6wks-18yrs?

A

RSV

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175
Q

What is the most common cause of pneumonia in the elderly?

A

Strep pneumo

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176
Q

What is the most common cause of pneumonia in young adults (18-40)?

A

Mycoplasma pneumonia

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177
Q

What is the most common cause of pneumonia in adults?

A

Strep pneumo

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178
Q

What is the most common cause of pneumonia in hospital setting?

A

Gram negatives

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179
Q

What is the most common cause of pneumonia in neonates?

A

Group B strep

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180
Q

What is the most common cause of pneumonia in COPD?

A

H. Flu

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181
Q

What is the most common cause of pneumonia in patients with cystic fibrosis?

A

kids-Staph aureus

Adults- psuedomonas

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182
Q

What is the most common cause of aspiration pneumonia?

A

Anaerobes

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183
Q

What is the most common cause of pneumonia in alcoholics/IV drug abusers?

A

Strep pneumo then klebsiella

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184
Q

What is the treatment for a patient with active TB?

A

2 months of isoniazide, rifampin, ethambutol and pyrazinamide then 4 months of isoniazide and rifampin.

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185
Q

What should you always give with isoniazide to prevent peripheral neuritis?

A

Vitamin B6

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186
Q

What is the treatment for latent TB with a positive PPD test?

A

9 months of isoniazide

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187
Q

What is the side effect of ethambutol?

A

optic neuritis

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188
Q

What is the side effect of rifampin?

A

turns body fluids orange

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189
Q

What is the side effect of isoniazide?

A

Peripheral neuropathy and hepatitis

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190
Q

What is the treatment for strep throat?

A

Penicillin

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191
Q

What can give you odynophagia, trismus, muffled voice, and deviated uvula away from lesion?

A

Peritonsillar abscess

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192
Q

What is the test of choice for sinus imaging?

A

CT scan

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193
Q

What is the treatment for acute bacterial sinusitis?

A

Amoxicillin/clavulanate

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194
Q

What is the treatment for coccidioidomycosis?

A

Fluconazole

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195
Q

What is the most common cause of postviral pneumonia?

A

Staph aureus

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196
Q

What is the prophylactic treatment for meningitis?

A

Rifampin

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197
Q

What is the most common cause of meningitis for elderly patients?

A

Strep pneumo

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198
Q

What is the most common cause of meningitis for patients 6-60yrs?

A

N. meningitidis

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199
Q

What is the most common cause of meningitis for neonates?

A

Group B strep

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200
Q

What is the most common cause of meningitis for kids from 6months-6yrs?

A

Strep pneumo

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201
Q

If you find RBCs in CSF without a history of trauma what should you start to think of?

A

HSV encephalitis

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202
Q

What is the treatment for HIV encephalitis?

A

IV acyclovir

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203
Q

What is the treatment for CMV encephalitis?

A

IV ganciclovir

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204
Q

What type of infection gives you CSF with elevated proteins, low glucose, and elevated WBCs?

A

Bacterial meningitis

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205
Q

What type of condition gives you CSF with high elevated opening pressure?

A

Pseudotumor cerebri

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206
Q

If you have a patient with a triad of headache, fever, and focal neurological deficit what should you be suspicious of?

A

Brain abscess

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207
Q

What is the treatment for a pregnant HIV+ patient who is not currently being treated?

A

zidovudine for mom and baby

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208
Q

What is the only live vaccine you can give HIV+ patients?

A

MMR

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209
Q

What is the treatment for cryptococcal meningitis?

A

IV amphotericin B

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210
Q

An HIV+ patient from Ohio presents with low grade fever, dry cough, malaise, weight loss, hepatosplenomegaly, pancytopenia, hilar lymphadenopathy and palatal ulcers. What condition is this?

A

Disseminated TB

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211
Q

What is the treatment for PCP?

A

TMP-SMX

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212
Q

What organs does CMV hit?

A

eyes, brain, GI, lungs

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213
Q

Foamy macrophages with acid fast bacilli?

A

mycobacterium avium

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214
Q

How do you treat mycobacterium avium?

A

Clarithromycin

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215
Q

If i have an HIV+ patient with a CD4 cell count

A

Azithromycin

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216
Q

What is the treatment for toxoplasmosis?

A

pyrimethamine+sulfadiazine

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217
Q

What is the prophylactic treatment for toxoplasmosis?

A

TMP-SMX or pyrimethamine+dapsone

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218
Q

If i have HIV and a CD4 cell count

A

PCP

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219
Q

If i have HIV and a CD4 cell count

A

Toxoplasmosis

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220
Q

If i have HIV and a CD4 cell count

A

Mycobacterium avium

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221
Q

What condition gives you these 3 stages….1. painless transient papule or ulcer, 2. painfull swelling of inguinal nodes, 3. anal pruritus with discharge, rectal strictures, elepantiasis?

A

Lymphogranuloma venereum

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222
Q

What is the treatment for chlamydia?

A

doxycycline

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223
Q

What is Reiters syndrome?

A

conjunctivitis, urethritis, arthritis

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224
Q

What is the treatment for gonorrhea?

A

ceftriaxone

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225
Q

If i have a patient with a suspected UTI and increased urine pH what should i think of?

A

infection with proteus mirabilis

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226
Q

What is the treatment for an uncomplicated UTI?

A

Nitrofurantoin or TMP-SMX 3-5days

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227
Q

What is the treatment for a UTI in a pregnant woman?

A

Nitrofurantoin 3-7days

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228
Q

What is the treatment for complicated UTI?

A

TMP=SMX or nitrofurantoin for 7-14days

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229
Q

What is first line therapy for pyelonephritis?

A

Fluoroquinolones

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230
Q

What is the first line chemoprophylaxis for chloroquine resistant malaria?

A

Mefloquine

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231
Q

What happens if you give a patient with mono ampicillin?

A

They develop a maculopapular rash

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232
Q

What rash starts on the wrists and ankles and spread centrally?

A

Rocky mountain spotted fever

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233
Q

What is the imaging test of choice for osteomyelitis?

A

MRI

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234
Q

Which immunosuppressant can cause gum hypertrophy?

A

cyclosporine

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235
Q

What is the treatment for dermatitis herpatiformis?

A

Dapsone

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236
Q

What condition could give you proximal muscle weakness in the lower extremities, difficulty ascending or descending stairs or rising from a seated position?

A

Polymyositis

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237
Q

What condition gives you recurrent pyogenic infections at 6 months of age with decreased concentrations of IgG, IgA, IgM, and IgE along with decreased B cells?

A

Brutons agammaglobinemia

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238
Q

What is the treatment for malignant otitis externa?

A

Ciprofloxacin

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239
Q

What can give you envelope shaped crystals?

A

ethylene glycol poisoning

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240
Q

What back condition is excerbated by exstension of the spine (standing and walking downhill) and relieved by flexion (sitting and walking uphill)?

A

Lumbar spinal stenosis

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241
Q

What are the serious side effects associated with cyclophospamide?

A

hemorrhagic cystitis, bladder carcinoma, sterility and myelosuppression

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242
Q

How can you prevent the toxic affects of cyclophosphamide?

A

hydration and MESNA

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243
Q

What is the most common cause of pneumonia in nursing home residents?

A

Strep pneumo

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244
Q

What is the treatment for bacterial meningitis in immunocompromised patients?

A

Vancomycin, ampicillin, cefepime

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245
Q

What is the treatment for bleeding esophageal varices?

A

octreotide

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246
Q

If you have a patient in pre-term labor and it is determined that her baby has bilateral renal agenesis what is the next step in management of the patient?

A

Allow spontaneous vaginal delivery because the condition is incompatible with life

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247
Q

What condition can present after travel or being on a cruise ship and give you a pneumonia like illness with high fever, watery diarrhea, headache, confusion, and hyponatremia?

A

Legionella

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248
Q

How do you treat legionella?

A

Fluoroquinolone

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249
Q

What is advanced sleep phase disorder?

A

Inability to stay awake in the evening after 7pm. Leads to early morning insomnia

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250
Q

What is delayed sleep phase syndrome?

A

Inability to fall asleep at normal bedtimes (10pm-midnight)

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251
Q

What condition can give you acne with monomorphous erythematous papules distributed over the face, arms, and trunk with no open or closed comedones?

A

Sterid acne

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252
Q

what is the main pathopysiologic mechanism underlying acne vulgaris?

A

Androgen excess

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253
Q

When do you do hip ultrasound in a baby with hip dysplasia?

A

2wks-6months

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254
Q

When do you do hip x-ray in a baby with hip dysplasia?

A

4-6months

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255
Q

Which medication is contraindicated in cocaine induced chest pain?

A

Beta blockers

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256
Q

What is the drug of choice for cocaine induced chest pain?

A

Nitrates or calcium channel blockers

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257
Q

What condition can give you an IgM spike and hyperviscosity?

A

Waldenstroms macrogliobinemia

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258
Q

Patient has difficulty reading fine print and has to hold reading material at an arms length in order to read them. What condition does he have?

A

Presbyopia

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259
Q

What is the abnormality in presbyopia?

A

Loss of elasticity in the lens

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260
Q

What eye problem gives you central visual field loss in a patient over age 50?

A

Age related macular degeneration

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261
Q

What eye condition has increased lens opacity and difficulty with night vision and driving at night?

A

Cataracts

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262
Q

What eye condition has elevated intraocular pressure, peripheral visual field defects followed by central visual loss?

A

Open angle glaucoma

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263
Q

If a patient is determined to be legally brain dead do you need permission to take him off life support?

A

NO!

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264
Q

What radiologic finding is associated with pseudogout?

A

Chondrocalcinosis

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265
Q

What is the most common ear pathology in patient with HIV?

A

Serous otitis media

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266
Q

What kind of shoulder injury give you an abducted arm that externally rotated?

A

Anterior shoulder injury

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267
Q

What kind of shoulder injury gives you an adducted arm thats internally rotated?

A

Posterior disclocation

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268
Q

What kind of injury do you get when you fall on an outstretched hand?

A

Colles fracture (distal radius)

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269
Q

If you have a positive valgus stress test what does that tell you?

A

Medial collateral ligament tear

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270
Q

If you have a positve varus stress test what does that tell you?

A

Lateral collateral ligament

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271
Q

In a motor vehicle accident when you have a dashboard injury what conditions does that predispose you to?

A

Posterior disclocation of the hip and PCL injury

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272
Q

What nerve can cause wrist drop?

A

Radial nerve

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273
Q

What nerve can cause foot drop?

A

Peroneal nerve

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274
Q

What nerve can cause claw hand?

A

ulnar nerve

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275
Q

What nerve can be injured in a anterior shoulder disclocation?

A

Axillary nerve

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276
Q

What condition causes pain with reptitive stress and resisted strength testing?

A

Tendinitis

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277
Q

What condition can cause bowel or bladder dysfunction, impotence, and saddle area anesthesia?

A

cauda equina syndrome

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278
Q

What is the treatment for a herniated disk?

A

NSAIDS

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279
Q

What condition gives you lower back pain that radiates to the arms, buttocks, and legs and improves upon flexion at the hips?

A

Spinal stenosis

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280
Q

What condition can give you a soap buble appearance x-ray?

A

Giant cell tumor of bone

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281
Q

What is the treatment for an acute attack of gout?

A

NSAIDS

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282
Q

Whats a side effect of hydroxychloroquine?

A

retinal toxicity

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283
Q

What condition gives you splenomegaly, rheumatoid arthritis and neutropenia?

A

Felty syndrome

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284
Q

Which joint is spared in RA but is present in OA?

A

DIP joint

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285
Q

What endocarditis is associated with lupus?

A

libman Sacks endocarditis

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286
Q

What is the treatment for Raynauds phenomenon?

A

Calcium channel blockers

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287
Q

What is the treatment for fibromyalgia?

A

Antidepressant

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288
Q

What condition causes pain and stiffness in the shoulder and pelvic girdles?

A

polymalgia rheumatica

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289
Q

What is the treatment for polymalgia rheumatica?

A

Steroids

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290
Q

What condition presents in a kid with arthritis and evanescent salmon colored rash?

A

Juvenile idiopathic arthritis

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291
Q

What is the time frame to use tPA in a stroke?

A

within 3hrs from onset of symptoms

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292
Q

How do you treat increased ICP?

A

Mannitol and hyperventilation raising the head of the bed

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293
Q

In the setting of severe hypertension or hemorrhagic stroke what is the treatment?

A

IV labetalol or nicardipine

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294
Q

If you have 100% occlusion of a carotid artery should you do a carotid endarterectomy?

A

NO!!!!

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295
Q

What is the single greatest risk factor for stroke?

A

HTN

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296
Q

What kind of condition can cause pseudodementia in the elderly?

A

subdural hematoma

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297
Q

If you have an intracerebral hemorrhage and start to develop a fixed dilated pupil that goes down and out what should you think of?

A

Uncal herniation

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298
Q

What neurotransmitter is associated with migraine headaches?

A

Serotonin

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299
Q

red wine in a young female is a trigger for what condition?

A

migraine

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300
Q

How do you prophylactically treat a migraine headache?

A

Anticonvulsants, beta blockers, CCB, TCA’s

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301
Q

If you have already developed a migraine headache what is the treatment?

A

NSAIDS or triptans

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302
Q

What bacteria is the most common cause of carvernous sinus thrombosis?

A

Staph aureus

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303
Q

What is the imaging test of choice for cavernous sinus thrombosis?

A

MRI

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304
Q

What kind of seizure has progressive jerking of body regions, hallucinations, but no loss of consciousness?

A

Simple partial seizure

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305
Q

What kind of seizure has episodes of lip smacking associated with impaired level of consciousness followed by confusion?

A

Complex partial seizure

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306
Q

What is the treatment of choice for partial seizures?

A

phenobarbital

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307
Q

What is the treatment for acute seizures lasting longer than 2 minutes?

A

benzodiazepine

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308
Q

What is the treatment for generalized tonic clonic seizures?

A

Phenytoin

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309
Q

What condition gives you a 3 second spike and wave discharge pattern?

A

Absent seizure

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310
Q

What is the first line treatment for an absent seizure?

A

Ethosuximide

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311
Q

What is the second line treatment for an absent seizure?

A

Valproic acid

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312
Q

How do you induce an absent seizure?

A

hyperventilation

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313
Q

What conditions gives the following EEG finding…. hypsarrhythmia?

A

infantile spasm

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314
Q

What is the treatment for infantile spasm?

A

ACTH

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315
Q

What condition gives you an EEG finding of slow spike and wave complexes?

A

Lenox-Gastaut syndrome

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316
Q

What is benign paroxysmal positional vertigo?

A

Condition where you get episodic short lived vertigo and nystagmus induced by postitional head changes. Not associated with nausea or vomiting

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317
Q

What is the abnormality in benign paroxysmal positional vertigo?

A

dislodged otolith

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318
Q

What is the treatment for benign paroxysmal positional vertigo?

A

Modified Epley maneuver

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319
Q

What condition can give you recurrent vertigo with auditory symptoms?

A

Menieres disease

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320
Q

What condition can give you acute onset of severe vertigo, gait instability, nausea, vomiting and nytstagmus?

A

Acute vestibular neuritis or labyrinthitis

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321
Q

What condition causes recurrent vertigo without auditory symptoms?

A

Vestibular migraine

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322
Q

What condition gives you proximal muscle weakness that gets worse as the day progresses. Also has dysarthria, dysphagia, ptosis and double vision?

A

Myasthenia Gravis

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323
Q

What are some associated finding with mysthenia gravis?

A

thyrotoxicosis and thymoma

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324
Q

What is the diagnostic test for myasthenia gravis?

A

Edrophonium (tensilon) test

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325
Q

What is the treatment for myasthenia gravis?

A

pyridostigmine

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326
Q

What type of multiple sclerosis gives you the best prognosis?

A

relapsing and remitting

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327
Q

What is the treatment for multiple sclerosis?

A

interferon

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328
Q

What is the treatment for acute excerbations for multiple sclerosis?

A

Corticosteroids

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329
Q

How do you diagnose guillian-barre syndrome?

A

nerve conduction studies and CSF with elevated proteins

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330
Q

What is the treatment for guillian-barre syndrome?

A

Plasmapheresis and IVIG

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331
Q

What is the most common cause of death in alzheimers patients?

A

aspiration pneumonia or other infections

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332
Q

How do you definitively diagnose alzheimers disease?

A

autopsy

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333
Q

What condition causes significant changes in behavior and personality?

A

Picks disease

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334
Q

Whats abnormal in Picks disease?

A

Atrophy of the frontal and temporal lobes

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335
Q

What condition gives you myoclonic jerks, ataxia and dementia?

A

Creutzfeldt-Jakob disease

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336
Q

What is the inheritance for hungtington disease?

A

Autosomal dominant

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337
Q

bilateral hand tremor is associated with what condition?

A

Essential tremor

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338
Q

What is the inheritance for neurofibromatosis?

A

Autosomal dominant

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339
Q

What chromosomes can you find defect on for neurofibromatosis 1 and 2?

A

Chromosome 17 and 22

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340
Q

What are some symptoms of neurofibromatosis type 1?

A

cafe au lait spots, optic glioma, lisch nodules, neurofibromas

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341
Q

Bilateral acoustic neuromas are associated with what condition?

A

Neurofibromatosis type 2

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342
Q

What condition is associated with ash-leaf spots, mental retardation and convulsive seizures?

A

Tuberous sclerosis

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343
Q

What heart condition is associated with tuberous sclerosis?

A

Rhabdomyoma

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344
Q

What is the dominant hemisphere?

A

left hemisphere

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345
Q

Where is broca’s area located?

A

posterior inferior frontal gyrus

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346
Q

In Brocas aphasia what happens to repetition?

A

Repetition is impaired

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347
Q

Where is the defect in Wernickes’s aphasia?

A

posterior superior temporal gyrus

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348
Q

A hard dilated painful red eye is associated with what condition?

A

closed angle glaucoma

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349
Q

What medication should you avoid in closed angle glaucoma?

A

Atropine

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350
Q

Headaches triggered by darkness is associated with what condition?

A

closed angle glaucoma

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351
Q

A fundoscopic exam that shows cupping of the disc and loss of peripheral vision is associated with what condition?

A

open angle glaucoma

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352
Q

What is the diagnostic test for open angle glaucoma?

A

Tonometry

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353
Q

What condition is associated with a cherry red spot and sudden painless unilateral blindness?

A

Central retinal artery occlusion

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354
Q

When should you hear fetal heart tones?

A

10-12wks

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355
Q

When should you appreciate fetal movement?

A

17-18wks

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356
Q

When is ultrasound most reliable to determine gestational age?

A

first trimester

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357
Q

When can you start to see a intrauterine pregnancy on ultrasound?

A

B-hCG of 1000-1500

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358
Q

When should you get a B-hCG level?

A
  1. Diagnose pregnancy
  2. Diagnose and follow ectopic pregnancy
  3. monitor trophoblastic disease
  4. Screen for fetal aneuploidy
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359
Q

How is the renal flow and GFR affected in pregnancy?

A

Both increases

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360
Q

How much folic acid is needed to prevent neural tube defects in a lady with history of neural tube defects in previous pregnancy?

A

4mg

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361
Q

How much folic acid is needed in pregnant women?

A

0.4mg

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362
Q

On your initial OB visit what test are you ordering?

A

CBC, Rh factor, type and screen, UA and culture, rubella antibody titer, HBsAg, RPR/VDRL, gonorrhea and chlamydia, PPD, HIV, Pap smear, tay-sachs and cystic fibrosis

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363
Q

When should the Quad screen be offered?

A

15-22wks

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364
Q

When do you do the glucose tolerance test in pregnancy?

A

24-28wks

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365
Q

When do you do the RhoGAM for Rh- women?

A

28wks

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366
Q

When do you do the GBS culture?

A

35-40wks

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367
Q

What does the QUAD screen consist of?

A
  1. MSAFP
  2. Inhibin A
  3. B-hCG
  4. Estriol
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368
Q

What is the QUAD screen useful for?

A

Detecting chromosomal abnormalities

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369
Q

What things can cause an elevated AFP level?

A

neural tube defects, incorrect dating, abdominal wall defects, fetal death, multiple gestation, placental abruption

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370
Q

What things can cause a reduced AFP?

A

Trisomy 21 and 18, incorrect dating, fetal demise

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371
Q

What is PAPP-A?

A

This is an associated pregancy protein that is screened for at 9-14wks that can detect trisomy 18 and 21

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372
Q

What would the quad screen show for a patient with down syndrome?

A
  1. AFP decreased
  2. Estriol decreased
  3. B-hCG increased
  4. Inhibin A increased
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373
Q

What would the quad screen show for a patient with edwards syndrome?

A
  1. AFP decreased
  2. Estriol decreased
  3. B-hCG decreased
  4. Inhibin A decreased
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374
Q

What is chorionic villus sampling?

A

Test done around 10-12wks gestation where you aspirate placental tissue for genetic diagnosis.

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375
Q

What is amniocentesis?

A

Test done around 15-20wks gestation where you aspirate amniotic fluid for genetic diagnosis.

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376
Q

When is an amniocentesis indicated?

A
  1. Advanced maternal age(>35)
  2. RH sensitized pregnancy
  3. Abnormal quad screen
  4. determine fetal lung maturity
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377
Q

What is a spontaneous abortion?

A

Loss of pregnancy prior to 20th wk of pregnancy

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378
Q

What is the most common cause of first trimester spontaneous abortion?

A

chromosomal abnormalities

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379
Q

What torch infection gives you periventricular calcifications?

A

CMV

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380
Q

What torch infection gives you blueberry muffin purpuric rash, hearing loss and cataracts?

A

Rubella

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381
Q

What torch infection gives you hydrocephalus, chorioretinitis, and intracranial calcifications?

A

Toxoplasmosis

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382
Q

What torch infection gives failure to thrive, bacterial infections and increase incidence of upper and lower respiratory tract infections?

A

HIV

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383
Q

What torch infection gives you snuffles, saddle nise, maculopapular rash, and hepatomegaly?

A

Syphilis

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384
Q

What is the treatment for an incomplete spontaneous abortion?

A

manual aspiration or a D&C

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385
Q

What is the treatment for intrauterine fetal demise?

A

Induce labor

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386
Q

What is the management of HSV in a pregnant women in the third trimester?

A

If the patient has active lesions upon delivery then perform a C-section

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387
Q

How many cm is the active stage of labor?

A

4cm-10cm

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388
Q

What are the stages of labor?

A
  1. Onset of cervical dilation
  2. Complete cervical dilation until the delivery of the baby
  3. Delivery of baby until the delivery of placenta
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389
Q

What are some reasons for fetal bradycardia on heart rate monitor?

A

Cord prolapse, uterine hyperstimulations, and rapid fetal descent

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390
Q

What are some reasons for fetal tachycardia on heart rate monitor?

A

maternal fever, hypoxia, fetal anemia

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391
Q

What is a normal reactive non stress test?

A

Greater than 2 accelerations of 15bpm above baseline lasting for 15 seconds over a period of 20minutes

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392
Q

If you have a nonreactive stress test what is the next step in management?

A

Biophysical profile

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393
Q

What is a biophysical profile?

A

A test that uses a real time ultrasound to assign a score measuring fetal tone, fetal breathing, amniotic fluid, movement, and NST

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394
Q

What is the amniotic fluid value for oligohydramnois?

A

AFI

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395
Q

If morning sickness persists beyond the first trimester what condition should you think of?

A

hyperemesis gravidarum

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396
Q

What are some causes of hyperemesis gravidarum?

A

Multiple gestations, first pregnancy, or molar pregnancy

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397
Q

What is the next step in management if you suspect a patient to have hyperemesis gravidarum?

A

rule out molar pregnancy with ultrasound and BhCG

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398
Q

What is considered abnormal for a 50gram glucose tolerance test performed at 24-28wks gestation?

A

> 140mg/dL

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399
Q

If you have an abnormal 50gram glucose tolerance test what is the next step in management?

A

Confirm with a 3hr 100gram oral glucose tolerance test

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400
Q

What are the abnormal valies for a 3hr 100 gram oral glucose tolerance test?

A
  1. Fasting >95
  2. 1hr >180
  3. 2hr >155
  4. 3hr> 140
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401
Q

What are the goal glucose numbers for a patient with gestational diabetes?

A

Fasting

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402
Q

What is the most common complication for a pregnant women with uncontrolled pregestational diabetes?

A

congenital malformations

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403
Q

What if a patient is a prediabetic and is pregnant what are her glucose goals?

A

Fasting is

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404
Q

What is the cutoff to be diagnosed as gestational HTN?

A

HTN that develops >20wks gestation

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405
Q

What are the appropriate HTN medications to use in pregnancy?

A

Methyladopa, labetalol, nifedipine

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406
Q

What is preeclampsia?

A

Condition in pregnancy occurring after 20wks gestation where the patient develops HTN, proteinuria and edema

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407
Q

What is the cutoff to be determined to have proteinuria associated with preeclampsia?

A

> 300mg

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408
Q

What are the characteristics of severe preeclampsia?

A
  1. BP >160/110
  2. proteinuria >5g
  3. headache
  4. blurred vision
  5. HELLP syndrome
  6. RUQ pain
  7. Clonus
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409
Q

What are some signs of magnesium toxicity?

A

Loss of DTRs, respiratory paralysis and coma

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410
Q

How do you treat magnesium toxicity?

A

IV calcium gluconate

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411
Q

What is the karotype for a complete molar pregnancy?

A

46XX

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412
Q

Which molar pregnancy contains fetal tissue?

A

Incomplete molar pregnancy

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413
Q

What is the karotype for incomplete molar pregnancy?

A

69XXY

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414
Q

Which molar pregnancy does not contain fetal tissue?

A

complete molar pregnancy

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415
Q

A snowstorm appearance on pelvic ultrasound is characteristic of what condition?

A

Molar pregnancy

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416
Q

What is considered postpartum hemorrhage?

A

> 500ml for vaginal deliveries

>1000ml for C-section

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417
Q

What is the management for severe postpartum hemorrhage?

A

uterine artery embolization

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418
Q

What condition causes hypogonadotropin deficiency and anosmia?

A

Kallman syndrome

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419
Q

What is the age for premature menopause

A

before age 40

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420
Q

What is the diagnostic test sequence for a patient with suspected secondary amenorrhea?

A
  1. pregnancy test
  2. TSH/prolactin
  3. progestin challenge
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421
Q

What is the meaning of a progestin challenge test coming back positive?

A

Means there is anovulation.

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422
Q

What is the meaning of a progestin challenge test coming back negative?

A

Means there is estrogen deficiency

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423
Q

The classic triad of pain, menorrhagia, and enlarged uterus is associated with what condition?

A

Adenomyosis

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424
Q

What is the test of choice for endometriosis?

A

Laparoscopy or laparotomy

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425
Q

What is the treatment for endometriosis?

A

OCPs

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426
Q

What is the most common complication of endometriosis?

A

Infertility

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427
Q

What is treatment for menorrhagia?

A

OCPs or mirena IUD

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428
Q

A young female presents with a fever and abdominal pain with a positive chandelier sign what condition are these symptoms associated with?

A

Tubo-ovarian abscess

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429
Q

What is the most common complication of tamoxifen therpay?

A

Endometrial cancer

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430
Q

If your pap smear shows ASCUS what is the next step in management?

A

HPV test

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431
Q

If your pap smear shows ASCUS and you do a HPV test and it comes back negative what is the next step in management?

A

repeat pap smear in 1yr

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432
Q

If your pap smear shows ASCUS and you do a HPV test and it comes back positive what is the next step in management?

A

Colposcopy

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433
Q

What is urinary incontinence caused by coughing, sneezing or lifting?

A

Stress incontinence

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434
Q

What is the treatment for urinary stress incontinence?

A

Pessary, kegal exercises and vaginal vault suspension surgery

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435
Q

What kind of urinary incontinence is caused presented by a strong urge to void?

A

Urge incontinence

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436
Q

What is the treatment for urge incontinence?

A

Anticholinergics or TCAs

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437
Q

What type of urinary incontinence is presented by chronic urinary retension?

A

Overflow incontinence

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438
Q

What is the treatment for overflow incontinence?

A

Urethral catheter

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439
Q

What breast condition causes bloody nipple discharge?

A

Intraductal papilloma

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440
Q

What is the screening test for a female under 30 who presents with a breast mass?

A

Ultrasound

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441
Q

If you have a HER2/neu positive cancer what is the treatment?

A

Trastuzumab

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442
Q

If you have a estrogen and progesterone positive breast cancer what is the treatment?

A

Tamoxifen

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443
Q

What is the prophylactic treatment for a transplant patient against opportunistic infections?

A

TMP-SMX

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444
Q

What are the PFT finding is COPD?

A
  1. decreased FEV1/FVC ratio
  2. normal-decreased FVC
  3. normal -increased TLC
  4. decreased DLco
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445
Q

What drugs can cause interstitial lung disease?

A

Amiodarone, bleomycin, and nitrofurantoin

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446
Q

What is the treatment for sarcoidosis?

A

steroids

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447
Q

eggshell calcifications are associated with what condition?

A

silicosis

448
Q

What is a complication of silicosis?

A

TB

449
Q

What is the treatment for ARDS?

A

PEEP

450
Q

popcorn calcification are associated with what?

A

benign lung nodule

451
Q

What condition can cause hypovolemia and a high normal pulmonary capillary wedge pressure in a MVA and after fluid resusciation the PCWP increases but does not correct the blood pressure?

A

Myocardial contusion

452
Q

What are the lab results for polymalgia rheumatica?

A

Elevated ESR and CRP

453
Q

What is the treatment for vaginal canidiasis?

A

Fluconazole

454
Q

If you have a patient with abnormal quad screen results suggesting down syndrome, what is the next step in management of the patient?

A

Ultrasound to assess amniotic fluid and fetal growth or malformations

455
Q

What is cell free dna testing?

A

Used for patient with abnormal quad screen results

456
Q

What test are good for fetal karotyping in pregnancy?

A

CVS and amniocentesis

457
Q

Where are medulloblastomas located?

A

cerebellar vermis

458
Q

What are some complications of PEEP therapy?

A
  1. alveolar damage
  2. tension pneumothorax
  3. hypotension
459
Q

What affect does PEEP therapy have on FRC?

A

increases FRC

460
Q

If you have mildly elevated TSH levels and normal circulating thyroid hormones what condition should you be worried about?

A

subclinical hypothyroidism

461
Q

If you have elevated thyroid hormones with normal TSH levels what condition should you be worried about?

A

Generalized resistance to thyroid hormones

462
Q

If you have high levels of TSH and low levels of circulating thyroid hormones what condition should you be worried about?

A

Primary hypothyroidism

463
Q

If you have low or inappropriately normal levels of TSH and low levels of thyroid hormones what condition should you be worried about?

A

secondary/tetriary hypothyroidism

464
Q

If a patient has a chronic scar with a nonhealing painless bleeding ulcer what condition should you think of?

A

Squamous cell carcinoma

465
Q

What is the next diagnostic step for sqamous cell carcinoma of the skin?

A

Punch, shave, or excisional biopsy

466
Q

What eye condition presents with loss of fundus details a sudden loss of vision and onset of floaters?

A

Vitreous hemorrhage

467
Q

What is the most common cause of vitreous hemorrhage?

A

Diabetic retinopathy

468
Q

What cardiac enzyme is useful to detect reinfarctions?

A

CK-MB

469
Q

Target sign of x-ray/ultrasound is associated with what condition?

A

intussusception

470
Q

If you have a newborn with feeding intolerance, lethargy abdominal distension and bloody stools what condition should you suspect?

A

necrotizing enterocolitis

471
Q

If a patient has symptoms suggestive of BPH what is the diagnostic test that should be ordered?

A

urinalysis

472
Q

What is a normal rhinne test?

A

AC>BC

473
Q

What does it suggest if you have an abnormal rhinne test?

A

BC>AC and you have conductive hearing loss

474
Q

With a webber test how do you determine if the test is normal?

A

If the sound is equal in both ears

475
Q

With a webber test how do you determine if you have conductive hearing loss?

A

The sound lateralizes to the affected ear

476
Q

With a webber test how do you determine if you have a sensineural hearing loss?

A

The sound is heard louder in the opposite ear

477
Q

What is the most common pathogen implicated in a subacute (>3months) prosthetic joint infection?

A

Staph epidermis

478
Q

What is the most common pathogen implicated in a acute (

A

Staph aureus

479
Q

What condition presents with a patient who has a history of normal skin at birth that gradually progresses to dry scaly skin?

A

ichthyosis vulgaris

480
Q

What causes vitiligo?

A

Autoimmune destruction of melanocytes

481
Q

What exam finding can still be observed in a patient who is brai dead?

A

Deep tendon reflexes

482
Q

What are the inhalation injuries you should suspect in house fires?

A

carbon monoxide and cyanide posioning

483
Q

What is the antidote for cyanide poisoning?

A

hydroxocobalamin or sodium thiosulfate

484
Q

Vesicles and erosions on the dorsum of the hands are characteristic of what condition?

A

Porphyria cutanea tarda

485
Q

If you have a patient with porphyria cutanea tarda what disease should you be screening for?

A

Hepatitis C

486
Q

Essential mixed cryoglobulinemia is associated with what underlying disease?

A

Hepatitis C

487
Q

What is the most likely cause of edema when a patient has edema while the leg is dependent but improves when the leg is elevated?

A

Venous valve incompetence

488
Q

What affect does antipsychotics have on prolactin?

A

Antipsychotics are dopamine blockers and dopamine blockers cause increase prolactin

489
Q

What is the treatment for stress incontinence?

A

Kegal exercises and urethropexy

490
Q

What is the treatment for urge incontinence?

A

Oxybutynin therapy

491
Q

What is the abnormality in urge incontinence?

A

detrusor hyperactivity

492
Q

What is the abnormality in stress incontinence?

A

dysfunction or urethral sphincter

493
Q

What is the treatment for overflow incontinence?

A

Bethanechol or alpha blockers

494
Q

If you have a patient in a MVA who has chest pain and once you give IV fluids there hpoxemia worsens what condition should you suspect?

A

Pulmonary contusion

495
Q

What is the treatment for sarcodosis?

A

steroids

496
Q

Loss of pain and temperature sensation in a cape-like distribution and upper extremity weakness is associated with what condition?

A

Syringomyelia (fluid filled cavity in spinal cord)

497
Q

Between folate and B12 which one depletes faster if it is lacking in the diet?

A

Folate

498
Q

What is the treatment for lactation suppression?

A

Tight fitting bra and ice packs and pain medication

499
Q

Delayed closure of anterior fontanelle, bony prominences of costochondral junctions, genu varum, and pliable skull bones without step offs are associated with what condition?

A

Rickets

500
Q

What are some risk factors for rickets?

A

exclusive breastfeeding, increased skin pigmentation and decreased sun exposure

501
Q

The term cor pulmonale refers to what?

A

Right heart failure

502
Q

HIT predisposes you to what complication?

A

arterial thrombosis

503
Q

Clear cell adenocarcinoma of the vagina and cervix are associated with what?

A

In utero exposure to DES

504
Q

bite cells and heinz bodies are associated with what condition?

A

glucose-6-phosphate dehydrogenase deficiency

505
Q

Doughy skin is a symptom of what condition?

A

Hypernatremia

506
Q

Which electrolyte abnormality can cause hypokalemia?

A

Hypomagnesemia

507
Q

Which electrolyte abnormality has a characteristic prolonged QT interval?

A

hypocalcemia

508
Q

What are some characteristic symptoms of hypomagnesemia?

A

hyperactive reflexes, seizures, arrhythmias

509
Q

What is the treatment for RTA type 1?

A

replace bicarbonate

510
Q

What is the treatment for RTA type 2?

A

thiazide diuretic

511
Q

What is different about RTA type 4?

A

Its caused by aldosterone defciency or resistance, you get acidic urine and you get hyperkalemia

512
Q

If you have white cells and eosinophils in your urine what condition should you think of?

A

acute interstitall nephritis

513
Q

If you have red blood cell casts or dysmophic red blood cells in your urine what condition should you think of?

A

glomerulonephritis

514
Q

If you have granular casts, renal tubular cells or muddy brown casts in your urine what condition should you think of?

A

Acute tubular necrosis

515
Q

If you have white cells and white cell casts in your urine what condition should you think of?

A

pyelonephritis

516
Q

If you have hyaline cast in your urine what should you think of?

A

normal urine sediment or volume depletion

517
Q

What are these values for someone with prerenal azotemia? BUN/CR, Fractional Na, urine sodium, urine osmality

A
  1. BUN/Cr- >20:1

2. fractional Na- 500

518
Q

What are these values for someone with acute tubular necrosis? BUN/CR, Fractional Na, urine sodium, urine osmality

A
  1. BUN/Cr- 1%
  2. Urine Na- >20
  3. Urine osmolality-
519
Q

Which glomerular disease gives you a low C3 level?

A

post strep glomerulonephritis

520
Q

What is the treatment for Wegeners granulomatosis?

A

steroids

521
Q

Histology shows linear anti-GBM deposits?

A

Goodpastures syndrome

522
Q

Prescence of c-ANCA?

A

wegners granulomatosis

523
Q

Histology shows fusion of epithelial foot processes?

A

minimal change disease

524
Q

What is the treatment for minimal change disease?

A

steroids

525
Q

What nephrotic syndrome is associated with IV drug abuse and HIV?

A

focal segmental glomerulosclerosis

526
Q

Histology shows spike and dome pattern and associated with hep B virus?

A

Membranous nephropathy

527
Q

Histology shows tram track appearance?

A

membranoproliferative nephropathy

528
Q

Staghorn calculi are associated with what kind of stones and whats the etiology?

A

Struvite stones from proteus

529
Q

Which kind of stones do you want to alkalinize the urine for?

A

uric acid and cystine stones

530
Q

Which stones are radiolucent?

A

uric acid stones

531
Q

Which stones have hexagonal crystals and positive urinary cyanide nitroprusside test?

A

cystine stones

532
Q

What is the imaging test of choice for adult polycystic kidney disease?

A

Ultrasound

533
Q

What is the diagnostic test for hydronephrosis?

A

ultrasound

534
Q

If you have a male infant with a distended palpable bladder and low urine output what condition should you suspect?

A

Posterior urethral valves

535
Q

When should you order a VCUG?

A
  1. Any boy presenting with first UTI

2. Any girl

536
Q

What is cryptorchidism?

A

Failure of 1 or both testes to descend into the scrotum

537
Q

Does cryptorchidism have an increased risk for testicular malignancy?

A

YES!!!

538
Q

What is the treatment for cryptorchidism?

A

Orchiopexy by 6-12months

539
Q

Does bringing the testes into the scrotum decrease the risk of testicular cancer in cryptorchidism?

A

NO!!!

540
Q

Patient comes in with painless scrotal swelling and the scrotum transilluminates. Whats the diagnosis?

A

Hydrocele

541
Q

Patient comes in with painless scrotal swelling and the scrotum has a bag of worms appearance. It does not transilluminate. What is the diagnosis?

A

Varicocele

542
Q

Patient comes in with painful scrotal swelling and the pain is relieved by elevating the scrotum. What condition is this?

A

Epididymitis

543
Q

Patient comes in with painful scrotal swelling and the pain is not relieved by elevating the scrotum. What condition is this?

A

Testicular torsion

544
Q

Which scrotal swelling condition give you loss of the cremasteric reflex?

A

testicular torsion

545
Q

What medications can cause erectile dysfunction?

A

Beta blockers, SSRIs, TCA, diuretics

546
Q

What is the recommended screening method for prostate cancer?

A

Annual DRE after age 50

547
Q

What kind of cancer is bladder carcinoma?

A

Transitional cell carcinoma

548
Q

What is the imaging test of choice for bladder cancer?

A

cystoscopy

549
Q

Older man presents with hematuria, flank pain and a flank mass. What is the diagnosis?

A

renal cell carcinoma

550
Q

B-hCG in a male is characteristic of what?

A

testicular choriocarcinoma

551
Q

What is the treatment for a seminoma?

A

Chemotherapy

552
Q

What fracture are pathognemomic for child abuse in kids?

A

Spiral fracture of humerus and femur, bucket fracture (jerking arms), posterior rib fracture (squeezing chest)

553
Q

What can you find on opthalmologic exam that can point you towards child abuse?

A

retinal hemorrhages

554
Q

Which congenital heart defect presents with severe cyanosis within the first few hours of life?

A

Transposition of the great vessels

555
Q

What is the most common cause of congenital heart disease?

A

VSD

556
Q

What is the most common cyanotic congenital heart lesion in the newborn?

A

Transposition of the great vessels

557
Q

What has to happen for transposition of the great vessels to be compatible with life?

A

Have to have a PDA and VSD or ASD

558
Q

What are the risk factors for transposition of the great vessels?

A

diabetic mother and digeorge syndrome

559
Q

What is digeorge syndrome?

A
  1. Cardiac anomlies
  2. abnormal facies
  3. Thymic aplasia
  4. cleft palate
  5. hypocalcemia
  6. 22q11 deletion
560
Q

What is the most common cyanotic congenital heart disease in children?

A

Tetralogy of fallot

561
Q

What would you see on CXR for a newborn with transposition of the great vessels?

A

egg on the side

562
Q

What is the treatment for transposition of the great vessels?

A

prostaglandin to keep the PDA open

563
Q

What are the 4 anomalies of tetralogy of fallot?

A
  1. Pulmonic stenosis
  2. Overriding aorta
  3. right ventricular hypertrophy
  4. VSD
564
Q

What is the normal growth pattern for infants?

A
  1. Double weight by 4-5months
  2. Triple weight by 1yr
  3. Quadruple weight by 2yrs
565
Q

What is the age of onset of puberty in girls?

A

10-12yrs

566
Q

What is the age of onset of puberty in boys?

A

12-14yrs

567
Q

What is the age of precocious puberty for boys?

A
568
Q

What is the age of precocious puberty for girls?

A
569
Q

What is klinefelters syndrome?

A

Condition of hypogonadism in males with a 47XXY that presents with testicular atrophy, gynecomastia, tall stature, and female hair distribution

570
Q

What is the most common cause of primary amenorrhea?

A

Turners syndrome

571
Q

What is the abnormality in PKU?

A

decreased phenyalanine hydroxylase

572
Q

What is the abnormality and symptoms in Nieman-Pick disease?

A

deficiency in sphingomyelinase with symptoms of cherry red spot and hepatosplenomegaly

573
Q

What is the abnormality in Tay-Sachs disease and what are the symptoms?

A

Lysosomal storage disease caused by a deficiency in hexosaminidase presents with slowed development and regression and cherry red spot

574
Q

little kid presents with colicky abdominal pain, vomiting and bloody stool. What condition are you thinking of?

A

Intussusception

575
Q

What is the test of choice for intussusception?

A

Ultrasound

576
Q

What would the ultrasound show for intussusception?

A

target sign

577
Q

What is the pathognemonic physical exam finding for intussusception?

A

sausage shaped abdominal mass in the RUQ

578
Q

What is the treatment for intussusception?

A

Air constrast enema

579
Q

What medication can cause pyloric stenosis?

A

erythromycin

580
Q

What is the imaging test of choice for pyloric stenosis?

A

ultrasound

581
Q

A little kid presents with sudden intermittent painless rectal bleeding…what condition are you suspecting?

A

Meckels diverticulum

582
Q

What is the imaging test of choice for meckels diverticulum?

A

Technitium 99 scan

583
Q

What is the imaging test of choice for hirschsprung disease?

A

Barium enema

584
Q

How do you definitively diagnose hirschsprung disease?

A

rectal biopsy

585
Q

Baby presents in the first month of life with bilious vomiting and crampy abdominal pain, distention and passage of bloody stool. What is the diagnosis?

A

Malrotation

586
Q

What is the imaging test of choice for malroation?

A

upper GI series

587
Q

Pneumatosis intestinalis on abdominal x-ray is pathognomonic for what condition?

A

necrotizing enterocolitis

588
Q

What is the enzyme deficiency in SCID?

A

adenosine deaminase

589
Q

What is the treatment for chronic granulomatous disease?

A

TMP-SMX

590
Q

What condition can cause delayed separation of the umbilical cord?

A

Leukocyte adhesion deficiency

591
Q

What immunodeficiency causes albinism, peripheral neuropathy, and neutropenia?

A

Chediak-Higashi syndrome

592
Q

What immunologic condition causes hyper IgE, eczema, and abscesses of the skin?

A

Job syndrome

593
Q

What is the treatment for kawasaki disease?

A

aspirin and IVIG

594
Q

What is the treatment for acute otitis media?

A

High dose amoxicillin

595
Q

What is laryngotracheobronchitis?

A

croup

596
Q

Patient comes in leaning forward in tripod position and has their neck hyperextended and the chin protruding…What condition are you suspecting?

A

epiglottis

597
Q

What is the management of epiglottis?

A

endotracheal intubation in the OR and IV antibiotics like ceftriaxone

598
Q

What is the gold standard for diagnosing pertussis?

A

culture

599
Q

What is the treatment for pertussis?

A

erythromycin

600
Q

Cough, coryza, conjunctivitis and koplik spots goes with what condition?

A

Measles

601
Q

Kid presents with high fever. After the fever subsides a maculopapular rash appears. What is the dianosis?

A

Roseola

602
Q

What causes roseola?

A

HHV-6 and 7

603
Q

What causes hand foot and mouth disease?

A

coxsackie A virus

604
Q

What APGAR score requires rescucitation?

A

0-3

605
Q

What causes RDS in infants?

A

surfactant deficiency

606
Q

Retained amniotic fluid and prominent perihilar streaking in interlobular fissures is associated with what condition?

A

transient tachypnea of the newborn

607
Q

Air bronchograms and ground glass appearance on CXR is characteristic of what condition?

A

RDS

608
Q

Double bubble sign on abdominal x-ray is associated with what condition?

A

duodenal atresia

609
Q

Child comes in with an abdominal mass that is painless and does not cross the midline, aniridia and hemihypertrophy. What is the diagnosis?

A

Wilms tumor

610
Q

Child comes in with a abdominal mass that crosses the midline, opsoclonus/myoclonus. What is the diagnosis?

A

neuroblastoma

611
Q

What is the best diagnostic step after suspecting neuroblastoma?

A

24hr urine VMA and HVA

612
Q

If a patient has leukocoria what does that suggest?

A
  1. Retinoblastoma
  2. Retinopathy of prematurity
  3. Cataracts
613
Q

Strabismus becomes a problem after what age?

A

3months

614
Q

If you have a egg allergy what vaccine cant you receive?

A

MMR and influenza

615
Q

What are the live vaccines you should avoid in pregnant and immunocompromised patients?

A
  1. Polio
  2. Varicella
  3. MMR
616
Q

What lives vaccines are okay to give HIV patients?

A
  1. Varicella

2. MMR

617
Q

Abdominal pain, vomiting and wrist or foot drop are associated with what?

A

lead poisoning

618
Q

What does the peripheral blood smear show for lead poisoning?

A

microcytic hypochromic anemia and basophilic stippling

619
Q

What glascow coma scale number warrants intubation?

A
620
Q

Patient presents with absent breath sounds on one side, hypotension, distended neck veins, hypoxemia, and tracheal deviation. What is the diagnosis?

A

tension pneumothorax

621
Q

What is the next step in management after tension pneumothorax is suspected?

A

Needle decompression

622
Q

If you suspect urethral injury what is the test of choice?

A

retrograde urethrogram

623
Q

If a previously stable chest trauma patient suddenly dies what should you suspect?

A

air embolism

624
Q

If a new diastolic murmur presents after chest trauma what should you suspect?

A

aortic dissection

625
Q

What should you suspect if a patient comes in from a MVA and CT shows blurring and punctate hemorrhaging along the gray-white matter junction?

A

Diffuse axonal injury

626
Q

Patient presents with paradoxical movement of his chest upon inspiration. What condition should we suspect?

A

flial chest

627
Q

What is the treatment for flial chest?

A

oxygen and narcotics

628
Q

What is a positive kehrs sign?

A

This is when you have shoulder pain due to diaphragmatic irritation from a splenic rupture

629
Q

A burn that is painless, white and charred is what kind of burn?

A

third degree burn

630
Q

What layers are involved in a 3rd degree burn?

A

epidermis and full thickness dermis

631
Q

What layers of the skin are involved in a first degree burn?

A

epidermis

632
Q

A burn that is painful and has blisters present is what kind of burn?

A

second degree burn

633
Q

What layer of the skin is involved in a second degree burn?

A

epidermis and partial thickness of the dermis

634
Q

What is the parkland formula for burns?

A

fluids for the first 24hrs= 4xWeight in kg x %BSA

635
Q

What is the treatment for malignant hyperthermia?

A

dantrolene

636
Q

What are the cause of postop fevers?

A
  1. WInd
  2. Water
  3. Walking
  4. Wounds
  5. Wonder drugs
  6. Womb
637
Q

What is the treatment for neuroleptic malignant syndrome?

A

dantrolene

638
Q

What animals contain rabies?

A

skunks, racoons, foxes, bats

639
Q

What can induce malignant hyperthermia?

A

halothane

640
Q

What happens with cardiac output, PCWP, and PVR in hypovolemic shock?

A
  1. CO= decreased
  2. PCWP=decreased
  3. PVR=increased
641
Q

What happens with cardiac output, PCWP, and PVR in cardiogenic shock?

A
  1. CO= decreased
  2. PCWP= increased
  3. PVR= increased
642
Q

What happens with cardiac output, PCWP, and PVR in obstructive shock?

A
  1. CO= decreased
  2. PCWP= increased
  3. PVR= increased
643
Q

What happens with cardiac output, PCWP, and PVR in septic shock?

A
  1. CO=increased
  2. PCWP= decreased
  3. PVR= decreased
644
Q

What happens with cardiac output, PCWP, and PVR in anaphylactic shock?

A
  1. CO= increased
  2. PCWP decreased
  3. PVR= decreased
645
Q

Which way does carbon monoxide move the hemoglobin-dissociation curve?

A

to the left

646
Q

What is the lab test you should look for if you are suspecting carbon monoxide poisoning?

A

carboxyhemoglobin

647
Q

Patient presents with ataxia, frquent falls, dysarthria, scoliosis and “hammer toe deformity”. What condition are you suspecting?

A

Friedreich ataxia

648
Q

What is the most common cause of death in Friedreich ataxia?

A

Cardiomyopathy

649
Q

What test can compare two means?

A

two-sample t test

650
Q

What test can compare three means?

A

ANOVA

651
Q

What is the recommendation for exercise in a pregnant patient?

A

moderate intensity exercise for atleast 30min 5-7days a week

652
Q

What exercise activities are unsafe in pregnancy?

A
  1. contact sports
  2. high risk falls
  3. scuba diving
  4. hot yoga
653
Q

Which antipsychotic has been implemented in cause high prolactin levels?

A

risperdone

654
Q

What is the karotype for a patient with complete androgen insensitivity?

A

46XY

655
Q

What is absent in a patient with complere androgen insensitivity?

A

uterus, vagina, axillary and pubic hair

656
Q

What is the karotype for mullerian agenesis?

A

46XX

657
Q

What is absent in mullerian agensis?

A

uterus and vagina

658
Q

In a patient with cryptorchid gonads, when should they undergp gonadectomy?

A

After puberty

659
Q

What kind of drug is odansetron and what is it useful for?

A

serotonin antagonist and its useful for chemotherapy induced nausea and vomiting

660
Q

What is the first step in management for a patient who presents with a stroke within 4hrs?

A

tPA

661
Q

What is the first step in management for a patient who presents with a stroke after 4hrs?

A

Aspirin

662
Q

What is the next step in management for a patient who presents with a recurrent stroke who is already taking aspirin?

A

give aspirin + dypyridamol or clopidogrel

663
Q

How do you calculate the anion gap?

A

Na- (bicarb+Cl)

664
Q

Pulsus paradoxus is associated with what heart condition?

A

cardiac tamponade

665
Q

Bounding pulses are associated with what heart condition?

A

aortic regurgitation

666
Q

Pulsus parvus et tardus is associated with what heart condition?

A

aortic stenosis

667
Q

What is the prophylactic treatment for rheumatic heart disease and how long should they be treated?

A

Penicillin. treatment should be for 10yrs or until the patient is 21

668
Q

If you have an elavated WBC count and elevated leukocyte alkaline phosphatase(LAP) what should you suspect?

A

Leukemoid reaction

669
Q

Whar causes molluscum contagiosum?

A

Poxvirus

670
Q

What are some ways you can prevent recurrent kidney stones?

A
  1. reduce sodium intake
  2. reduce protein intake
  3. normal calcium intake
  4. thiazide diuretic
  5. alkalinization of urine
  6. reduce oxalate
  7. increase fluids
  8. allopurinol
671
Q

What is the managment for pheochromocytoma?

A

First give alpha blocker then beta blocker

672
Q

What is the mutation for the most severe form of neurofibromatosis type 2?

A

nonsense mutation

673
Q

What is the mutation for the milder form of neurofibromatosis type 2?

A

missense

674
Q

What is the treatment for trigeminal neuralgia?

A

Carbamazepine

675
Q

What is the imaging test for suspected shaken baby syndrome?

A

nonconstrast CT scan

676
Q

What condition can cause a abdominal succussion splash?

A

pyloric stricture

677
Q

What is a risk factor for pyloric stricture?

A

acid ingestion which leads to fibrosis and formation of pyloric stricture

678
Q

Patient presents with early satiety, nausea, vomiting and weight loss with a history of acid ingestion. What is the diagnosis?

A

Pyloric stricture

679
Q

What is the treatment for acute decompensated heart failure?

A
  1. Oxygen
  2. loop diuretic
  3. Nitrates
680
Q

What causews edema of the hands and feet in Turners syndrome?

A

dysgenesis of the lymphatic network

681
Q

What organism is partially acid fast with filamentous branching rods?

A

Nocardia

682
Q

What is the test of choice after myasthenia gravis has been confirmed and why do you perform that test?

A

CT scan of chest looking for thymoma

683
Q

How does tamoxifen affect osteoporosis?

A

decreases the risk of osteoporosis

684
Q

What condition of ulcerative colitis requires regular surveillance?

A

colorectal carcinoma

685
Q

She asymptomatic gallstones be treated?

A

NO!!!

686
Q

What is the ankle brachial index test useful for?

A

Peripheral artery disease

687
Q

What is an abnormal ankle-brachial index?

A
688
Q

What is the most common side effect of levodopa/carbidopa?

A

hallucinations

689
Q

What is the treatment for Guillian-barre syndrome?

A

IVIG or plasmapheresis

690
Q

What is the preferred method of contraception in a postpartum women who is breastfeeding?

A

progestin only oral contraceptives

691
Q

A pulmonary nodule with a “halo sign” is characteristic of what?

A

Aspergillosis

692
Q

What is the staging modality in gastric adenocarcinoma?

A

CT scan

693
Q

Do you find crypt abscess in crohns or UC?

A

UC

694
Q

Do you find abdominal pain and bloody stools in crohns or UC

A

UC

695
Q

Do you find pseudopolyps in crohns or UC?

A

UC

696
Q

Do you find granulomas in crohns or UC?

A

crohns

697
Q

What is Kussmauls sign?

A

increase in JVD with inspiration

698
Q

Patient presents with inferior MI, hypotension, JVD, kussmauls breathing and clear lung sounds. What is the diagnosis?

A

right ventricular infarct

699
Q

What is the treatment for a right ventricular infarct?

A

IV fluids

700
Q

What is the most common cause of endocarditis in IV drug abusers?

A

Staph aureus

701
Q

What is the treatment for infective endocarditis in IV drug abusers?

A

Vancomycin

702
Q

A gardener presents with a painless ulcer on their finger that spreads along their forearm. What are you thinking of?

A

Sporotrichosis

703
Q

Patient presents with a tick bite from the south like arkansas with confusion and no rash. What are you suspecting?

A

ehrlichiosis

704
Q

Patient presents with recurrent oral ulcers and genital ulcers, eye lesions, and skin lesions. What is the diagnosis?

A

Behcet’s syndrome

705
Q

bone age

A

constitutional growth delay

706
Q

If you have a patient under 65 with chronic liver disease what pneumococcal vaccine should they receive?

A

PCV23 only

707
Q

If a patient is over 65 yrs old what pneumococcal vaccine should they receive?

A

PVC13 followed by PCV23

708
Q

When a patient has sickle cell anemia when do you do blood transfusion instead of hydroxyurea therapy?

A
  1. Acute stroke
  2. Acute chest syndrome
  3. aplastic crisis
  4. anemia
709
Q

What is the next best step after electrical burn?

A

EKG

710
Q

What topical burn medication cannot penetrate an eschar but causes hypokalemia and hyponatremia?

A

silver nitrate

711
Q

What topical burn medication can penetrate an eschar and hurts bad?

A

mefadine

712
Q

What topical burn medication cannot penetrate an eschar but causes leukopenia?

A

silver sulfadiazine

713
Q

What is the work-up for a penetrating injury to the neck in zone 1?

A

Aortagraphy

714
Q

What is the work-up for a penetrating injury to the neck in zone 3?

A

Aortagraphy and triple endoscopy

715
Q

What is the work-up for a penetrating injury to the neck in zone 2?

A

exploratory surgery

716
Q

If you have a chest x-ray showing free air under the diaphram what is the next step in management?

A

Surgery

717
Q

If you have a patient with a stab wound but they are stable what is the next step in management?

A

FAST scan

718
Q

If you perform a FAST scan and it comes back equivocal what is the next step in management?

A

Diagnostic perotineal lavage

719
Q

If you have a positive FAST scan or diagnostic peritoneal lavage what is the next step in management?

A

exploratory laparotomy

720
Q

Patient has blunt abdominal trauma with a handle bar sign. What is the most likely injured organ?

A

pancreas

721
Q

Patient presents with blunt abdominal trauma and is in stable condition. What is the next best step?

A

Abdominal CT

722
Q

Patient presents with shoulder pain following a seizure or electrical shock, what is the diagnosis?

A

Posterior shoulder dislocation

723
Q

Patient presents with a outwardly rotated arm and numbness over the deltoid, what is the diagnosis?

A

Anterior shoulder dilocation

724
Q

What is the genetic defect in malignant hyperthermia?

A

Ryanodine receptor gene defect

725
Q

What bugs can cause necrotizing fascitis?

A

strep and clostridium perfingens

726
Q

What are common cause of fever on Post-Op day 1?

A
  1. atelectasis
  2. Necrotizing fascitis
  3. Malignant hyperthermia
727
Q

What is lights criteria?

A

Tells you if a pleural effusion is transudative or exudative. If protein ratio

728
Q

WHat is the characteristic effusion seen with adenocarcinoma of the lung?

A

exudative effusion with high hyaluronidase

729
Q

What are the 3 diagnostic criteria for ARDS?

A
  1. bilateral fluffy infiltrates on x-ray

2. PaO2/FiO2

730
Q

What is the treatment for symptomatic hypercalcemia?

A

Short term-IV hydration and calcitonin

Long term- bisphosphanates

731
Q

What is the enzyme deficiency in Lesch_Nyhan syndrome?

A

Hypoxanthine-guanine phosporibosyl tranferase

732
Q

How does antipsychotics induce hypothermia?

A

inhibiting the body shivering mechanism and inhibiting autonomic thermoregulation

733
Q

What kind of cancer does OCPs increase your risk of getting?

A

cervical cancer

734
Q

What kind of cancer does OCPs decrease your risk of getting?

A

endometrial and ovarian cancer

735
Q

How does antipsychotics induce hypothermia?

A

inhibiting the body shivering mechanism and inhibiting autonomic thermoregulation

736
Q

What kind of cancer does OCPs increase your risk of getting?

A

cervical cancer

737
Q

What kind of cancer does OCPs decrease your risk of getting?

A

endometrial and ovarian cancer

738
Q

PAD increases your risk for what complication in the future?

A

myocardial infarction

739
Q

What is the therapeutic INR range for an idiopathic DVT?

A

2-3

740
Q

What is the therapeutic INR range for patients with prothetic valves?

A

2.5-3.5

741
Q

What type of heparin causes HIT?

A

unfractionated heparin

742
Q

What is the treatment for HIT?

A

leuprilide or argotraban

743
Q

If you are suspecting diverticulitis in a patient but the patient is not improving with antibiotic therapy what is your next step in management?

A

CT scan

744
Q

If you are suspecting a patient to have glaucoma what medication do you want to avoid?

A

atropine

745
Q

What is the antidote for iron intoxication?

A

deferoxamine

746
Q

kid presents with andominal pain hematemesis and metabolic acidosis after pills were found scattered on the floor. and abdominal films show small opacities in the stomach and duodenum. What did they ingest?

A

iron

747
Q

What is the pathology of pseudotumor cerebri?

A

impaired CSF absorption by arachnoid villi

748
Q

What is the treatment for pseudotumor cerebri?

A

weight reduction and acetazolamide

749
Q

What is the most significant complication in psedotumor cerebri?

A

blindness

750
Q

Patient has a tender mass palpated in the popliteal fossa, what do you suspect?

A

Baker cyst

751
Q

What causes a baker cyst?

A

excessive fluid production from inflamed synovium

752
Q

What is the reason for hypotension after giving a pregnant lady and epidural?

A

the sympathetic nerve fibers can become blocked and cause vasodilation and venous pooling

753
Q

Patient presents with unilateral transient loss of vision and says it felt like a curtain was falling down in my eye, what is the diagnosis?

A

Amaurosis fugax

754
Q

What causes Amaurosis fugax?

A

retinal emboli that are displaced

755
Q

Patient falls on an outstretched arm then the patient is unable to abduct their arms and they are also unable to adduct their arms smoothly without the arm falling quickly to the side. What kind of injury is this?

A

rotator cuff injury

756
Q

What is the defect in osteogenesis imperfecta?

A

Mutation in type 1 collagen

757
Q

What mechanism is employed in myocardial perfusion scanning when dipyridamole is given?

A

coronary steal phenomenon

758
Q

An x-ray finding of the knee with an expansile and eccentric lytic area describes what and is related to what condition?

A

soap bubble appearnace related to giant cell tumor of bone

759
Q

What things can trigger meniere’s disease?

A
  1. Alcohol
  2. Caffeine
  3. nicotine
  4. Salt
760
Q

If you have a patient with a solid testicular mass and ultrasound suggest that it is a testicular tumor what is the next step in management?

A

orchiectomy

761
Q

If you change the cutoff point to a higher cutoff point what happens to sensitivity and specificity?

A

sensitivity decreases and specificity increases

762
Q

What part of the brain is affected in hemi-neglect syndrome?

A

parietal lobe

763
Q

Whats elevated in seminomas

A

BhCG

764
Q

What is the most common vitamin deficiency in the US?

A

folic acid

765
Q

Patient presents with night blindness and dry skin what vitamin are they deficient in?

A

vitamin A

766
Q

What vitamin deficiency causes neonatal hemorrhage and increased PT and PTT?

A

vitamin K

767
Q

Patient presents with diarrhea, dermatitis and dementia, what is the diagnosis?

A

Pellegra

768
Q

What vitamin deficiency cause stomatitis and cheilosis? (crusting of the lips and mouth)

A

Vitamin B2(riboflavin)

769
Q

Patient presents with swollen gums, bruising, anemia and poor wound healing. What vitamin is deficient?

A

Vitamin C

770
Q

Selenium deficiency causes?

A

cardiomyopathy

771
Q

Magnesium deficiency causes?

A

muscle weakness and cramps, worsened hypocalcemia, tremor

772
Q

What are the symptoms of beri-beri?

A

polyneuritis, dilated cardiomyopathy, high cardiac output failure, edema

773
Q

What are the side effects of loop diuretics?

A

hypokalemia and ototoxcitiy

774
Q

What is the side effect of phenytoin?

A

gingival hyperplasia

775
Q

What is the defect in syringomelia?

A

central canal defect that causes impaired drainage of CSF (fluid filled cavity)

776
Q

What kind of accident commonly is associated with syringomyelia?

A

cervical whiplash accident

777
Q

What kind of bacteria is gram positive, anaerobic filamentous branching and colonizes the oral cavity?

A

actinomyces

778
Q

What is the preferred therapy for a patient with an actinomyces infection?

A

Penicillin

779
Q

What is chemoprophylaxis for HIV patients with a positive PPD test?

A

isoniazide and pyridoxine for 9months

780
Q

What is the biggest risk factor for raloxifene therapy?

A

DVT

781
Q

What is the difference between raloxifene therapy and tamoxifen therapy?

A

Tamoxifen therapy gives an increase risk for endometrial cancer and Raloxifene gives an increase risk for DVT

782
Q

Chondrocalcinosis is associated with what condition?

A

hemachromatosis

783
Q

What is the mechanism for SVT?

A

reentry into the AV node

784
Q

How does vagal maneuvers or medical therapy decrease SVT?

A

decrease AV node conductivity

785
Q

What is the picture for club foot?

A

calcaneum is in the varus position, midfoot is in the varus position and forefoot is in adduction

786
Q

What is the treatment for a child suspected of clubfoot?

A

immediate stretching, manipulation, followed by casting

787
Q

What chromosome abnormality is most consistent with cri-du-chat syndrome?

A

Chromosome 5

788
Q

What is the problem in pagets disease of bone?

A

disorganized bone remodeling

789
Q

How are osteoclast and osteoblast affected in paget disease of bone?

A

Osteoclast activity is increased

Osteoblast activity is increased

790
Q

What is the treatment for Giant Cell Arteritis?

A

High dose steroids

791
Q

What are the symptoms of bells palsy?

A
  1. Inability to raise eyebrow or close the eye
  2. drooping of the corner of the mouth
  3. Disappearance of the nasolabial fold
792
Q

What is the genetic inheritance for hemophilia?

A

X-linked recessive

793
Q

What condition do you use the D-xylose test to confirm?

A

celiac disease

794
Q

Which TORCH infection can cause anemia and hyperbilirubinemia?

A

syphilis

795
Q

What are the screening test for syphillis?

A
  1. RPR

2. VDRL

796
Q

What is the confirmatory test for syphilis?

A

FTA-ABS

797
Q

Periventricular calcifications in a newborn is characteristic of what?

A

CMV infection

798
Q

What is metoclopramide?

A

Its a dopamine antagonist drug used to treat nause, vomiting and gastroperesis

799
Q

What is the treatment for dystonic reactions,dyskinesia and parkinsonism?

A

benztropine

800
Q

If a patient obtains a needle stick from a known Hepatitis B person and the patient doesnt know their vaccination status, what is the next step in management?

A

Hepatitis B immunoglobin and Hepatitis B vaccination

801
Q

If a patient obtains a needle stick from a known Hepatitis B person and the patient is Hepatitis B immune, what is the next step in management?

A

Reassurance

802
Q

Patient presents with severe headache and vomiting. Patient is also seeing halos around lights. On physical exam she has a nonreactive dilated pupil what is the diagnosis?

A

acute angle closure glaucoma

803
Q

Which pulmonary renal syndrome requires plasmapheresis?

A

Goodpastures syndrome

804
Q

What is the treatment for Wegeners syndrome?

A

Cyclophospamide and steroids

805
Q

What is the treatment for uremic pericarditis?

A

Hemodialysis

806
Q

What is the bacteria that cuases infection from cat and dog bites?

A

Pasteurella multocida

807
Q

What is the treatment for a cat or dog bite?

A

Amoxicllin/clavulanate

808
Q

What is the treatment for narcolepsy?

A

Modafinil

809
Q

In a HIV positive person what opportunistic infection are you worried about with a CD4 cell count less than 50

A

Mycobacterium avium

810
Q

In a HIV positive person what opportunistic infection ae you worried about with a CD4 cell count less than 200

A

Pneumocystis jirovecii and oral candidiasis

811
Q

In a HIV positive patient what opportunistic infection are you worried about with a CD4 cell count less than 100

A

Toxoplasma gondii

812
Q

In a HIV positive patient with a CD4 count less than 150

A

Histoplasma

813
Q

What is the prophylactic treatment in a HIV positive patient with a CD4 count less than 150

A

itraconazole

814
Q

What is the prophylactic treatment in a HIV positive patient with a CD4 count less than 50

A

azithromycin

815
Q

What is the prophylactic treatment in a HIV positive patient with a CD4 count less than 200

A

TMP-SMX

816
Q

What is the prophylactic treatment for a HIV positive patient with a CD4 cell count less than 100

A

TMP-SMX

817
Q

What are some causes of non-anion gap metabolic acidosis?

A
  1. Diarrhea

2. RTA

818
Q

NSAIDS and lymphoma are associated with what kind of nephrotic syndrome?

A

minimal change

819
Q

African americans and HIV is associated with what kind of nephrotic syndrome?

A

Focal segmental glomerulosclerosis

820
Q

Hepatitis B and C are associated with what kind of nephrotic syndrome?

A

Membranoproliferative glomerulonephritis

821
Q

Lupus and Hepatitis B is associated with what kind of nephrotic syndrome?

A

Membranous nephropathy

822
Q

2month old baby presents with eczema, regurgitating of his milk, and painless bloody stools are associated with what condition?

A

Milk-protein induced entercolitis

823
Q

Patient presents with progressive vision loss in one eye and when looking at a set of parallel lines they appear wavy and bent to them, what is the diagnosis?

A

macular degeneration

824
Q

What is the primary risk factor for macular degeneration?

A

age

825
Q

Lens opacification is associated with what condition?

A

cataracts

826
Q

What is the inheritance pattern for myotonic muscular dystrophy?

A

autosomal dominant

827
Q

What is the inheritance pattern for duchenne and becker muscular dystrophy?

A

X-linked recessive

828
Q

Patient presents with facial weakness, dysphagia, myotonic handgrip and testicular atrophy, what condition should you be thinking of?

A

Myotonic muscular dystrophy

829
Q

Patient has irregular heavy vaginal bleeding, what is the next step in management to stop the bleeding?

A
  1. High dose estrogen
  2. High dose OCPs
  3. High dose progestin pills
830
Q

Patient presents with severe local lower back pain thats worse at night, lower extremity weakness, decreased spincter tone, and hyperactive deep tendon reflexes, what is the diagnosis?

A

Spinal cord compression

831
Q

What is the treatment for spinal cord compression?

A

steroids

832
Q

What condition causes severe itching after bathing?

A

Polycythemia vera

833
Q

What is the treatment for pertussis in a child less than 1month?

A

Azithromycin

834
Q

What is the treatment for pertussis in people greater than 1month?

A

Erythromycin

835
Q

Pelvic ultrasound shows enlarged ovary with decreased blood flow, what is the diagnosis?

A

Ovarian torsion

836
Q

Pelvic ultrasound shows free fluid near an ovarian cyst, what is the diagnosis?

A

Ruptured ovarian cyst

837
Q

What should you be thinking of when separating arterial thrombosis from arterial embolus?

A

Arterial thrombosis is a gradual process and Arterial embolus is a sudden process

838
Q

What are the side effects of ACE inhibitors?

A

cough, angioedema and hyperkalemia

839
Q

What are the side effects of loop diuretics?

A

Ototoxicity and hypokalemia

840
Q

What is the treatment for ITP?

A

IVIG or steroids

841
Q

When do you treat vs. observe an adult patient with ITP?

A

Observe: platelets>30,000
Treat: Platelets

842
Q

When do you observe vs treat children with ITP?

A

observe: only skin manifestations
Treat: Bleeding

843
Q

Patient presents with a recent upper respiratory infection and an enlarged mediatinum on chest x-ray. CT scan shows a mass in the “middle mediastinum” what is the likely diagnosis?

A

Bronchogenic cyst

844
Q

A popping sound in the knee followed by pain and swelling is associated with what kind of injury?

A

Meniscus tear

845
Q

What are the parameters assessed in a glascow coma scale?

A
  1. Eye opening
  2. Verbal response
  3. Motor response
846
Q

What is another name for Lynch syndrome?

A

Hereditary non-polyposis colorectal cancer

847
Q

What other condition is associated with Lynch syndrome?

A

endometrial carcinoma

848
Q

Patient presents with a systolic-diastolic abdominal bruit, what is the diagnosis?

A

renal artry stenosis

849
Q

How do you get a radial head subluxation? (nursemaid elbow)

A

pulling child arm or swinging child by the arms

850
Q

What is the treatment for nursemaid elbow?

A

hyperpronate the forearm

851
Q

MEN type 1?

A
  1. Primary hyperparathyroidism
  2. Pancreatic tumor
  3. Pituitary tumor
852
Q

MEN type 2A?

A
  1. Medullary thyroid carcinoma
  2. Pheochromocytoma
  3. Parathyroid hyperplasia
853
Q

MEN type 2B?

A
  1. Medullary thyroic cancer
  2. Pheochromocytoma
  3. Mucosal & intestinal neuroma
  4. Marfanoid habitus
854
Q

What are characteristics of lung consolidation?

A
  1. Dullness to percussion
  2. Bronchial breath sounds(louder)
  3. Prominent expiratory phase
  4. Egophony
  5. Crackles
855
Q

If you have mono how long should you refrain from playing sports?

A

> 3wks

856
Q

What is the most modifiable risk factor in osteoarthritis?

A

weight reduction

857
Q

Where is the most likely source for a DVT?

A

Proximal deep veins (iliac, femoral, popliteal)

858
Q

The symptoms of diffuse telangiectasias, recurrent epistaxis and AV malformations are associated with what condition?

A

Osler-Weber-Rendu syndrome

859
Q

What is the inheritance pattern for Osler-Weber-Rendu syndrome?

A

Autosomal dominant

860
Q

anti-topoisomerase 1 antibodies are associatd with what condition?

A

scleroderma

861
Q

Hydatid cyst come from which parasite?

A

Echinococcosis

862
Q

What animals carry Echinococcosis?

A

Sheep

863
Q

What organs can be affected by Echinococcosis?

A

Liver and lung

864
Q

What does infection with Echinococcosis cause?

A

Hydatid cysts

865
Q

What occupation is at hish risk for neurocysticercosis?

A

Pig farmers

866
Q

Kid presents with headache vomiting and visual distubances. They have limited ability of upward gaze with a tendency for downward gaze. What is the diagnosis?

A

Pinealoma

867
Q

What are the vaccinations for adults post-splenectomy?

A

Either 2weeks before or 2weeks after you need to get Meningococcal, PCV13, and H.flu

868
Q

Kid complains of progressive bone pain that occurs at night without relation to physical activity. What is the diagnosis?

A

Osteoid osteoma

869
Q

What is the treatment for osteiod osteoma?

A

NSAIDS

870
Q

What is the side effect of olanzapine?

A

weight and sedation

871
Q

Patient presents with a history of a whistling noise during respiration after undergoing a rhinoplasty, what is the diagnosis?

A

nasal septal perforation

872
Q

What kind of patient do you see with nasal polyps?

A

asthma or allergy patients

873
Q

What is the side effect of clozapine?

A

agranulocytosis and weight gain

874
Q

Patient presents with a history of smoking, shoulder pain, weakness in the hands and miosis and ptosis, what is the diagnosis?

A

pancoast tumor

875
Q

What is the treatment for pericarditis?

A

NSAIDS

876
Q

If a patient is 21-24yrs of age with a ASCUS pap smear what is the next step in management?

A

Repeat pap smear in 1 yr

877
Q

If a patient is 25 and older and has a pap test showing ASCUS what is the next step in management?

A

HPV test

878
Q

If a patient is 21-24 and has a pap test showing ASC-H what is the next step in management?

A

colposcopy

879
Q

If a patient is 21-24 yrs and has had 2 consecutive ASCUS pap smears what is the next step in management?

A

pap smear in 1 yr

880
Q

If you are a vegetarian what vitamin deficiency are you prone to?

A

B12

881
Q

What is the most common side effect of hydroxychloriquine?

A

retinopathy

882
Q

If you suspect breath holding spells what test should you run?

A

CBC and ferritin

883
Q

If the patient CSF contains EBV DNA what is the likely diagnosis?

A

Primary CNS lymphoma

884
Q

What are 3 primary risk factors for acute otitis media?

A
  1. Upper respiratory infection
  2. exposure to smoke
  3. formula feedings
885
Q

Boot shaped heart on x-ray is diagnostic of what condition?

A

Tetralogy of fallot

886
Q

What is the most common cause of viral arthrtitis?

A

Parvovirus B19

887
Q

What is the typical picture of a patient with viral arthritis?

A

Person who works in a daycar with arthrtitis that worse in the MCP, PIP and wrist joints

888
Q

Prolonged therapy with a PPI can increase your risk for what?

A

C.diff and osteoporosis

889
Q

What is the management for fibromyalgia?

A
  1. Exercise
  2. Good sleep hygiene
  3. Antidepressants
890
Q

What is the preferred treatment for hepatitis B infection?

A

tenofovir

891
Q

What are the indications for treatment in a patient with hepatitis B?

A
  1. Liver failure
  2. Infectious (HBe)
  3. High viral load (> 20,000)
  4. Cirrhosis
  5. Immunosuppressed
892
Q

Pale patches on the back that scale on scraping, what is the diagnosis?

A

Tinea versicolor

893
Q

What is the treatment for tinea versicolor?

A

ketoconazole

894
Q

What type of an environment is prone to grow tinea versicolor?

A

Hot and humid environments

895
Q

What is dark field microscopy?

A

confirmatory test for syphilis

896
Q

What is the most common bacteria in febrile neutropenia?

A

Psuedomonas

897
Q

What is the treatment for febrile neutropenia?

A

pipercillin-tazobactam

898
Q

Patient presents with a history of lupus for which she takes steroids and hip pain for the last 2 weeks. The pain has been increasing and there is no tenderness or warmth around the hip. Range of motion is normal and x-rays are normal. What is the diagnosis?

A

Avascular necrosis

899
Q

How do you confirm the diagnosis of avascular necrosis?

A

MRI

900
Q

What are the symptoms of anticholinergic toxicity?

A

dry mouth, dry skin, constipation, urinary retention, flushing, vision changes and confusion

901
Q

What is the first indicator of hypovolemia?

A

pulse rate

902
Q

What are the comorbidities of panic disorder?

A
  1. Depression
  2. Agoraphobia
  3. Substance abuse
903
Q

What is the management for kleptomania?

A

psychotherapy

904
Q

What is the imaging test of choice for fibroids?

A

ultrasound

905
Q

If a patient has an MI and a few hours late develops hypotension and kussmaul sign what is the likely diagnosis?

A

Right ventricular failure

906
Q

If a patient had an MI 3-5 days ago and develops severe pulmonary edema and a new systolic murmur what is the likely diagnosis?

A

Papillary muscle rupture

907
Q

If a patient had an MI 1 wk ago and develops hypotension and chest pain, jvd and distant heart sounds what is the likely diagnosis?

A

Ventricular free wall rupture

908
Q

If a patient had an MI 3-5 days ago and develops hypotension, chest pain, and new systolic murmur and failure of both ventricles, what is the likely diagnosis?

A

Interventricular septal defect

909
Q

What medications should be prescribed after an MI with PCI?

A

aspirin, clopidogrel, ACE, beta blocker, simvistatin

910
Q

What is the treatment for cervical adenitis?

A

Clindamycin

911
Q

What is the etiology of Duchenne muscular dystrophy?

A

Cuased by deletion of the dystrophin gene

912
Q

What is the etiology of beckers muscular dystrophy?

A

Reduced dystrophin gene with milder disease in older kids

913
Q

What are the complications of muscular dystrophy?

A

Cardiomyopathy

914
Q

What are the risk factors for osteoporosis?

A
  1. Post-menopausal
  2. low vitamin D/calcium intake
  3. steroid use
  4. lack of weight bearing exercises
  5. smoking
  6. alcohol
915
Q

What is the most common cause of non-melanoma skin cancer?

A

Basal cell carcinoma

916
Q

What is the single most important risk factor for squamous cell carcinoma?

A

sunlight exposure

917
Q

Which metal in jewelry most commonly causes contact dermatitis?

A

nickel

918
Q

Symptoms of hypokalemia?

A

muscle cramps, muscle weakness, hyporeflexia, fatigue, arrhythmias, flat T waves

919
Q

Patient presents with a sharpley demarcated, erythematous, edematous, tender skin lesion on their face with raised borders, what is the likely diagnosis?

A

Erysipelas

920
Q

What the causative organism for erysipelas?

A

Group A strep

921
Q

What is the defect in osteogenesis imperfecta?

A

Defect in type 1 collagen

922
Q

Blue sclerae and pathological bone fractures are associated with what condition?

A

Osteogenesis imperfecta

923
Q

What is the treatment for norcardia?

A

TMP-SMX

924
Q

A rash that consists of firm dome-shaped flesh colored papules with central umbilication is associated with what condition?

A

molluscum contagiosum

925
Q

What bug causes bacillary angiomatosis?

A

Bartonella

926
Q

What is the treatment for bacillary angiomatosis?

A

erythromycin

927
Q

What is the most common side effect of ECT therapy?

A

amnesia

928
Q

Patient with Turners syndrome are most at risk of developing what condition?

A

osteoporosis

929
Q

Pain between the third and fourth toes on the plantar surface with a clicking sensation, is likely what?

A

Mortons neuroma

930
Q

Point tenderness on the plantar aspect of the foot with burning pain in the morning that decreases with activity is likely what?

A

Plantar fascitis

931
Q

What is the treatment for a specific phobia?

A

behavioral therapy

932
Q

What pathogens are responsible for endometritis?

A

polymicrobial infection

933
Q

What is the treatment for endometritis?

A

clindamycin and gentamicin

934
Q

What are the pathogens that cause acute bacterial sinusitis?

A
  1. Strep pneumo
  2. non typaeable H. flu
  3. Moraxella catarrhalis
935
Q

What is the earliest renal abnormality present in patient with diabetes?

A

Glomerular hyperfiltration

936
Q

Patient presents with optic disc hyperemia, what did they ingest?

A

Methanol

937
Q

Which statistical test assess associations?

A

Chi square test

938
Q

What tremor likely occurs during rest and improves with activity?

A

Resting tremor of parkinsons

939
Q

What is Trihexyphenidyl?

A

An anticholinergic parkinson drug

940
Q

What is a common association with dermatomyositis?

A

malignancy

941
Q

When do you resort to imaging in a patient with uncomplicated pyelonephritis?

A

if no improvement after 2-3days

942
Q

High LAP levels are associated with what?

A

leukemoid reaction

943
Q

Low LAP levels are associated with what?

A

CML

944
Q

Nocturnal chest pain should alert you to what?

A

GERD

945
Q

In regards to methylmalonic acid and homocysteine what are the values in B12 and folate deficiency?

A

B12- elevated homocysteine and methylmalonic acid

Folate- elevated homocysteine and normal methylmalonic acid

946
Q

What is a risk factor for nasopharyngeal carcinoma?

A

EBV virus

947
Q

Which anemia gives you absent thumbs?

A

Fanconi anemia

948
Q

What is the difference between fanconi anemia and diamond-blackfan anemia?

A

DIamond-blackfan anemia is a red cell aplasia that gives you weird thumbs while fanconi anemia is a pancytopenia that gives you absent thumbs

949
Q

How does the knee to chest position help patient with tetraology of fallot?

A

Increases systemic vascular resistance

950
Q

Patient presents with a CD4 count less than 50 and eye exam shows yellow-white patches of retinal opacification and retinal hemorrhages, what is the diagnosis?

A

CMV retinitis

951
Q

What is the treatment for CMV retinitis?

A

ganciclovir or foscarnet

952
Q

What is the most common complication of vesicoureteral reflux disease?

A

renal scarring

953
Q

What is the imaging test of choice for diagnosing vesicouretal reflux disease?

A

VCUG

954
Q

If a kid has their first UTI what is the imaging test?

A

Renal bladder ultrasound

955
Q

If a kid has recurrent UTI’s what is the imaging test? w

A

VCUG

956
Q

What is the accepted treatment for ALS?

A

Riluzole

957
Q

What is a side effect of hydroxychloroquine?

A

retinopathy

958
Q

What are two complication of nephrotic syndrome?

A

Hyperlipidemia and hypercoagulablity

959
Q

What causes ebstein anomaly?

A

Lithium

960
Q

What are the side effects of isoretretinoin?

A

cranifascial defects, heart defects, and deafness

961
Q

What are the symptoms of HUS?

A
  1. microangiopathic hemolytic anemia
  2. Uremia
  3. Thrombocytopenia
962
Q

What are the three things that predispose diabetic patients for foot ulcers?

A
  1. neuropathy
  2. microvascular insufficency
  3. immunosuppression
963
Q

What are the risk factors for abdominal aortic aneurysm expansion and rupture?

A
  1. Active smoking
  2. growing in size
  3. Large diameter
964
Q

What are the risk factors for an abdominal aortic aneurysm?

A
  1. Age (>60)
  2. Family history
  3. athersclerosis
  4. caucasian
  5. smoking
965
Q

What are the indications to repair an abdominal aortic aneurysm?

A
  1. Symptomatic
  2. greater than 5.5cm
  3. rapidly expanding
966
Q

What is salvage radiation therapy?

A

therapy used when the original therapy failed and there is recurrence of disease

967
Q

hat does valsalva do to preload?

A

decreases preload because it decreases venous return to the heart

968
Q

What does standing do to preload?

A

Standing decreases preload and decreases venous return to the heart

969
Q

What does squatting do?

A

increases venous return and increases afterload and regurgitation

970
Q

What does handgripping do?

A

increases afterload and increases blood pressure and regurgitation

971
Q

Which murmurs get loader with valsalva

A

HOCM and MVP

972
Q

Which murmurs get loader with squatting?

A

aortic regurgitation, mitral regurgitation and VSD

973
Q

What is the difference between illness anxiety disorder and somatic symptom disorder?

A

In somatic symptom disorder a patient has anxiety about atleast 1 symptom that is unexplained while illness anxiety disorder has anxiety about having an illness when few or no symptoms are present and constant negative evals

974
Q

Patient presents with a long history of OCP use and a solid mass in the liver, what is the likely diagnosis?

A

Hepatic adenoma

975
Q

Multiple hepatic nodules of varying sizes is characteristic of what?

A

Liver metastasis

976
Q

Patient presents with liver problems who have been exposed to vinyl chloride and arsenic compounds, what is the likely diagnosis?

A

Hepatic angiosarcoma

977
Q

Patient presents with cafe au lait spots, precocious puberty and multiple bone defects, what is the likely diagnosis?

A

McCune-Albright syndrome

978
Q

What condition can give you altered mental status, gait instability, nystagmus, and conjugate gaze palsy?

A

Wernicke’s encephalopathy

979
Q

What is the cause of Wernicke’s encephalopathy?

A

Thiamine deficiency

980
Q

What is the drug of choice for osteoarthritis?

A

Acetaminophen

981
Q

If you develop HIT what is the managment?

A

Stop the heparin and give argatroban

982
Q

What is the manegement for uncomplicated diverticulosis?

A

increase dietary fiber intake

983
Q

How does diabetes affect cranial nerve 3?

A

If causes nerve ischemia of cranial nerve 3 which affects the somati fibers and causes ptosis and a down and out pupil

984
Q

What pancreatic complication is present 4 wks after an acute onset of pancreatitis?

A

pancreatic pseudocyst

985
Q

What is the imaging modality for pseudocyst?

A

ultrasound

986
Q

What is the management for a pancreatic pseudocyst?

A

observation

987
Q

If you have bilirubin in the urine what does that tell you?

A

That you have a build up of conjugated bilirubin

988
Q

What drugs can cause esophagitis?

A
  1. tetracyclines
  2. nsaids and aspirin
  3. potassium chloride
  4. aledronate
  5. iron
989
Q

What is the etiology of herpangina?

A

Coxsackie A virus

990
Q

What is the treatment for herpangina?

A

ice cream

991
Q

Patient presents with clusters of small vesicles on anterior oropharynx and lips, what is the likely diagnosis?

A

Herpetic gingivostomatitis

992
Q

What is the treatment for herpetic gingivostomatitis?

A

acyclovir

993
Q

Patient presents with gray vesicles/ulcers on tonsillar pillars, what is the likely diagnosis?

A

herpangina

994
Q

What is the etiology of endocarditis in patient with prosthetic valves, catheters, implanted devices, IV drug use?

A

Staph aureus

995
Q

What is the etiology of endocarditis in patients with dental procedures and biopsy of respiratory tract?

A

strep viridans

996
Q

What is the etiology of endocarditis in patients with UTIs?

A

enterococci

997
Q

What is the etiology of endocarditis in patients with colon cancer or IBD?

A

Strep bovis

998
Q

What is rivaroxaban?

A

It is a factor 10a inhibitor used in the managment of acute DVT or PE

999
Q

gallbladder wall thickening and pericholecystic fluid is associated with what condition?

A

Acalculous cholecystitis

1000
Q

What are the antiphospholipid antibodies associated with Lupus that are associated with thromboembolic disease?

A

lupus anticoagulant and anticardiolipin

1001
Q

What is the treatment for pinworms?

A

mebendazole

1002
Q

What is the treatment for limb ischemia?

A

Heparin bolus and vascular surgery consult

1003
Q

A patient with COPD presents with increased dyspnea, increased cough and increased sputum production, what is the likely diagnosis?

A

Acute COPD exacerbation

1004
Q

What is the management for a patient with COPD exacerbation?

A
  1. Oxygen
  2. Bronchodilator
  3. Steroids
  4. Antibiotics
  5. Positive pressure ventilation
1005
Q

What is indinavir?

A

Protease inhibitor for AIDS treatment

1006
Q

What is the side effect of indinavir?

A

crystal induced nephropathy

1007
Q

Classic triad of pain, jaundice, and palpable mass is most likely what?

A

biliary cyst

1008
Q

Patients with renal faiure who are on hemodialysis, what is the most common cause of death?

A

Cardiovascular disease

1009
Q

Which part of the bladder is most susceptible to rupture and peritoneal signs?

A

Bladder dome

1010
Q

What is Lights criteria for an exudative effusion?

A
  1. fluid protein/serum protein > 0.5
  2. fluid ldh/serum ldh >0.6
  3. fluid ldh > 2/3 upper limit
1011
Q

What conditions will you find a high amylase pleural effusion?

A

esophageal rupture or pancreatitis

1012
Q

What are the best markers indicating resolution of DKA?

A

serum anion gap and beta hydroxybutyrate levels

1013
Q

What is malignant hypertension?

A
  1. BP > 180/120

2. retinal hemorrhages, exudates, papilledema

1014
Q

What is a hypertensive emergency?

A

severe hypertension associated with malignant hypertension or hypertensive encephalopathy

1015
Q

What is hypertensive encephalopathy?

A

cerebral edema

1016
Q

What is the medical management for primary hyperaldosteronism?

A

aldosterone antagonist

1017
Q

descrescendo early dialstolic murmur?

A

Aortic regurgitation

1018
Q

What is the treatment for acute pancreatitis?

A

NPO, nasogastric tube suction, IV fluids, analgesics, antibiotics

1019
Q

What is the management for a patient presenting with placental abruption?

A

Stable patient- trial of vaginal delivery

unstable patient- C section

1020
Q

What is the most common cause of a nonreactive NST?

A

fetal sleep cycle

1021
Q

If you suspect a fetal sleep cycle causing a nonreactive NST what is the next step in management?

A

vibroacoustic stimulation

1022
Q

What are the complications of cryptorchidism?

A
  1. inguinal hernia
  2. subfertility
  3. testicular cancer
  4. testicular torsion
1023
Q

What is the management for cryptorchidism?

A

orchiopexy by 6-12months

1024
Q

For sickle cell anemia what will you see on peripheal blood smear?

A

sickle cells and howell jolly bodies

1025
Q

If you suspect a stillbirth because of absent fetal movement what is the next step in diagnosis?

A

ultrasound

1026
Q

Once a stillbirth is diagnosed what is the next step in management?

A

counsel the patient about delivery options

1027
Q

If you suspect central precocious puberty what is the next step in management?

A

MRI then GnRH agonist therapy

1028
Q

IV drug user presents with progressive lower back pain. On exam there is severe tenderness to gentle percussion over the vertebrae, what is the likely diagnosis?

A

vertebral osteomyelitis

1029
Q

What is the initial workup for vertebral osteomyelitis?

A

CBC, blood cultures, ESR, CRP and x-ray. Then do MRI

1030
Q

What two lab values can give you the best picture of acid base status?

A

pH and PaCO2

1031
Q

If you are suspecting a patient has Amaurosis fugax what is the next step in management?

A

Duplex study of neck

1032
Q

What is the most common complication of peptic ulcer disease?

A

hemorrhage

1033
Q

Atopic dermatitis is another word for what?

A

eczema

1034
Q

What are some things that can cause acute pancreatitis?

A
  1. Gallstones
  2. Alcohol
  3. Drugs (antibiotics, seizure meds, diuretics)
1035
Q

What part of the spine is most commonly affected in rheumatoid arthritis?

A

cervical spine

1036
Q

What are the test to run for a patient who comes in with suspected strep throat?

A

Rapid antigen test and throat culture

1037
Q

What are the side effects of methotrexate therapy?

A

oral ulcers, hepatotoxicity, pulmonary toxicity, bone marrow suppression, and alopecia

1038
Q

What can you give a patient to reduce the incidence of adverse effects of methotrexate?

A

folic acid

1039
Q

What is the management for a patient with suspected ventilator associated pneumonia?

A

First get a chest x-ray if its abnormal then do a lower respiratory tract sampling then empiric antibiotics

1040
Q

What bugs are associated with ventilator associated pneumonia?

A

Pseudomona, e.coli, klebsiella, MRSA

1041
Q

What causes viral myocarditis?

A

coxsackie B virus

1042
Q

What is the management for acute severe pain in a current or former addict?

A

IV morphine

1043
Q

What are upper motor neuron findings?

A

hyperreflexia and spascitity

1044
Q

What are lower motor neuron findings?

A

fasciculations

1045
Q

Contralateral hemiparesis and gaze palsy is a hemorrhage in what part of the brain?

A

basal ganglia

1046
Q

Occipital headache ataxia and nystagmus is a hemorrhage in what part of the brain?

A

cerebellum

1047
Q

Contralateral hemiparesis, constricted pupils and upgaze palsy is a hemorrhage in what part of the brain?

A

thalamus

1048
Q

contact lens keratitis is caused by what?

A

Pseudomonas

1049
Q

when do you give PCV23 alone?

A

When a patient is under 65 and has chronic heart, lung or liver condition or diabetes or smoker

1050
Q

In DKA what is your body most likely to be depleted of?

A

Potassium

1051
Q

What is the most likely cause of pneumonia in a HIV patient?

A

strep pneumo

1052
Q

What causes acute unilateral lympadenitis?

A

Staph aureus and group A strep

1053
Q

What causes the pruritis and flushing in niacin?

A

prostaglandin induced peripheral vasodilation

1054
Q

What is the cause of fanconi anemia?

A

Chromosomal breaks

1055
Q

What benign lesions of the eye are associated with primary biliary cirrhosis?

A

Xanthelasma

1056
Q

What can confirm the diagnosis of CLL?

A

Flow cytometry of the peripheral blood

1057
Q

What are the symptoms of zinc deficiency?

A

bad taste in mouth, rash, and poor wound healing

1058
Q

delayed fontanelle closure and bowing of the legs are associatd with what condition?

A

Rickets

1059
Q

Hemorrhagic disease of the newborn is caused by what?

A

vitamin K deficiency

1060
Q

An elderly patient presents with bleeding gums and bone pain who is on a tea and toast diet, what is the likely diagnosis?

A

vitamin C deficiency

1061
Q

Is hypospadias or epispadias associated with exstrophy of the bladder?

A

epispadias

1062
Q

Describe epispadias?

A

Penile anomaly where the urethra opens on the top side of the penis

1063
Q

Describe hypospadias?

A

Penile anomaly where the urethra opens on the bottom side of the penis

1064
Q

What is Potters syndrome?

A

Bilateral renal agenesis, abnormal facies, limb deformities, and lung hypoplasia

1065
Q

Patient describes a shade being pulled over their eye, what should you think of?

A

Amaurosis fugax

1066
Q

What is a indicator in the question stem that you are dealing with carotid stenosis?

A

TIA or Amaurosis fugax

1067
Q

What is the next step in mangement if you ae dealing with carotid stenosis?

A

duplex scan of the carotids

1068
Q

What is the management if you find 50% or less stenosis of the carotid artery?

A

Aspirin and/or clopidogrel

1069
Q

WHat is the management if you have greater than 70% stenosis of the carotid artery?

A

Carotid endarterectomy

1070
Q

Patient presents with a pulsatile abdominal mass and hypotension, what is the next best step?

A

exploratory laparotomy

1071
Q

What is the management of an acute dissection in the ascending aorta?

A

Surgery

1072
Q

What is the management of an acute dieesction in the descending aorta?

A

b-blockers

1073
Q

What is the classic presentation for chronic mesenteric ischemia?

A

Postprandial abdominal pain, a fear of food, and weight loss. Patient usually has a history of athersclerosis

1074
Q

A superficial palpbale cord is a specific sign for what?

A

Superficial thrombophlebitis

1075
Q

Patient presents with arm problems during exercise and CNS problems what is the diagnosis?

A

subclavian steal syndrome

1076
Q

What is the most common type of testicular cancer?

A

seminoma

1077
Q

What is the imaging test of choice for renal cell carcinoma?

A

abdominal CT scan

1078
Q

What is the size of a stone that is unlikely to pass on its own?

A

10mm

1079
Q

What is pulseless disease?

A

Takayasu arteritis

1080
Q

What is the treatment for Takayasu arteritis?

A

steroids

1081
Q

What is the treatment for Behcet syndrome?

A

steroids

1082
Q

What is the trreatment for polymyositis?

A

steroids

1083
Q

What could cause recurrent pneumonia in the same spot in a kid?

A

foreign body aspiration

1084
Q

Can you use oral hypoglycemics in pregnancy?

A

NO!!!!

1085
Q

If a patient has an abnormal NST and abnormal Biophysical profile, what is the next step in managment?

A

COntraction stress test

1086
Q

What is the treatment for a hydatiform mole?

A

D&C with serial B-hCG levels

1087
Q

When should you give the infant varicella zoster immunoglobin?

A

If the mother contracts varicella zoster within the last 5 days of the pregnanct or within 2 days post delivery

1088
Q

What is the order of fetal positions during normal labor and delivery?

A
  1. descent
  2. flexion
  3. internal rotation
  4. Extend
  5. external rotation
  6. expulsion
1089
Q

What antibodies can cross the placenta?

A

IgG

1090
Q

When do you give rhogam to treat RH imcompatability?

A

at 28wks and within 72hrs after delivery

1091
Q

What is the treatment for chorioamniotis?

A

ampicillin and gentamicin

1092
Q

What is the prophylaxis for group B strep?

A

Penicillin

1093
Q

What is the most common cause of postpartum hemorrage?

A

uterine atony

1094
Q

What is the treatment for scabies?

A

Permethrin cream

1095
Q

What is the treatment for lice?

A

Permethrin cream

1096
Q

WHat causes skin colored smooth waxy papules with a central umbilicated depression that are roughly 0.5cm?

A

Molluscum contagiosum

1097
Q

What is the treatment for pemphigus vulgaris and bullous pemphigoid?

A

Steroids

1098
Q

Between pemphigus vulgaris and bullous pemphigoid which one gives you oral lesions?

A

Pemphigus vulgaris

1099
Q

flesh colored lesion that grows rapidly with a central crater that contains keratinous material, what is the likely diagnosis?

A

Keratoacanthoma

1100
Q

What is the management for keratoacanthoma?

A

observation

1101
Q

What is bowen disease?

A

squamous cell cancer in situ

1102
Q

From what lesion does squamous cell cancer classically develop?

A

Actinic keratoses

1103
Q

What determines the prognosis of malignant melanom?

A

Depth of invasion

1104
Q

WHat is actinic keratoses?

A

premalignant lesion to squamous cell cancer where you get a red scaly plaque in chronic sun exposed areas

1105
Q

A unilateral red oozing or crusting nipple in an adult woman is what?

A

Paget disease of the nipple

1106
Q

What can cause stomatitis?

A

riboflavin, niacin, pyridoxine, vitamin C

1107
Q

What is the treatment for gonorrheal conjunctivitis?

A

ceftriaxone

1108
Q

WHat is the treatment for closed angle glaucoma?

A

pilocarpine

1109
Q

Catatracts in a neonate should suggest what?

A

TORCH infection or galactosemia

1110
Q

What changes in the retina are seen in diabetics?

A
  1. hemorrgaes
  2. microaneurysms
  3. neovascularization
1111
Q

What changes in the retina are seen in hypertension?

A
  1. artery narrowing
  2. wiring
  3. cotton wool spots
1112
Q

What are the most common bugs causing preseptal and orbital cellulitis?

A
  1. Strep pneumo
  2. H.Flu
  3. Staph aureus
1113
Q

What is the difference between a stye and a chalazion?

A

A stye is a painful red lump near the lid margin whereas a chalazion is a painless red lump away from the lid margin

1114
Q

classic dendritic keratitis on fluorescin stain is what?

A

Herpes simplex keratitis

1115
Q

What should be avoided in herpes simplex keratitis?

A

steroids

1116
Q

What condition is temporal arteritis associated with?

A

polymalgia rheumatica