STEP 1-Toxins and Antidotes Flashcards

1
Q

Acetaminophen

A

N-acetylcysteine (GSH replenish)

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2
Q

AChE inhibitors (organophosphates)

A

Atropine followed by pralidoxime

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3
Q

Amphetamines (basic)

A

NH4CL (acidify urine)

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4
Q

Antimuscarinic/anticholinergic agents

A

physostigmine salicylate (control hyperthermia)

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5
Q

Benzodiazapines

A

Flumazenil

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6
Q

B-blockers

A

glucagon

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7
Q

Carbon Monoxide

A

100%/hyperbaric O2

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8
Q

Copper/arsenic/gold

A

penicillamine

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9
Q

cyanide

A

Nitrite + thiosulfate, hydroxocobalamine

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10
Q

Digitalis

A

Anti-dig FAB fragments

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11
Q

Heparin

A

Protamine sulfate

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12
Q

Iron

A

Deferoxamine, deferasirox

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13
Q

Lead

A

EDTA, dimercaprol, succimer, penicillamine

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14
Q

Mercury, arsenic, gold

A

Dimercaprol (BAL), succimer

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15
Q

Methanol/ethylene glycol

A

fomepizole > ethanol, dialysis

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16
Q

Methemoglobin

A

methylene blue, vitamin C

17
Q

Opioids

A

Naloxone

18
Q

Salicylates

A

NaHCO3 (alkalinize urine), dialysis

19
Q

TCA’s

A

NaHCO3 (alkalinize plasma)

20
Q

tPA, streptokinase, urokinase

A

Aminocaproic acid

21
Q

Warfarin

A

Vitamin K, plasma (if active bleeding)