Stem cells Flashcards
What are stem cells
Stem cells are cells that have the ability to become various types of cells. They are present both during embryonic development and in the adult body
What does it mean when a cell is totipotent, pluripotent, multipotent, unipotent
Totipotent is the ability to develop into a new organism eg. Zygote
Pluripotent is the ability to become any type of cell in the body eg. Embryonic stem cells found in the blastocyst
Multipotent is the ability to develop specific types of cells (terminally differentiate cells) eg. Blood cells that become red/white blood cells
Unipotent are cells once they are differentiated
What is the process of a cell to become differentiated
Other genes in the cell will methylate as it will only express specific genes. Cells depend on cues to tell it what to turn into and these cues are further established by transcription factors (chemical in the cell that tells it what to turn on)
Fertilisation of egg & sperm into zygote then blastocyst (inner cell mass) and then specialised cells
What makes stem cells different to other cells
- They are self-sustaining & can continue to divide for a long period of time
- They are unspecialised
- They give rise to specialised cells (differentiation)