Stem Cells Flashcards
1
Q
What two types of stem cells are found in the bone marrow and what are there markers?
A
Haematopoietic - c-kit / Sca-1
Mesenchymal - CD105
2
Q
What are the markers of endothelial stem cells?
A
CD31
CD45-
3
Q
Where are satellite cells found?
A
Under the basal lamina of muscle fibres.
4
Q
What is the response of satellite cells to injury?
A
Activate and proliferate
Chemotaxis to injured fibre
Fuse to damaged fibre / fusion to produce new myofibres
Regenerated myofibres with central nuclei.
