STDs and a couple of add-ons Flashcards
High risk pops (STDs, chlamydia, syphilis)
youth
chlamydia: black>Hispanic>white
syphilis: MSM account for 72% cases 2011, high rate of HIV coinfection
Vulvovaginal Candidiasis causative organism(s)
NOT AN STD
(U) Candida albicans
can be caused by other Candida sp. or yeasts (Candida glabrata, Candida tropicalis or Torulopsis glabrata)
Vulvovaginal Candidasis epidemiology
COMMON!
at least 75% of women experience 1 episonde
40-45% experience>1 episode
Vulvovaginal Candidiases Clinical Presentation
-Vulvar pruritis, external dysuria, burning, dyspareunia, swelling, redness, excoriation
-thick, curd-like vaginal discharge
NORMAL VAGINAL pH (<4.5)
Vulvovaginal Candidiasis: Risk Factors
taking antibiotics
immunocompromise (eg. HIV, DM, steroids)
body w/warm, most environment
Vulvovaginal Candidiases: Dx
- clinical presentation
- Testing:
a. wet prep (saline & 10% KOH) w/microscope visualization of budding yeast & hyphae
b. Candida culture
- spaghetti & meatballs
Vulvovaginal Candidiasis: UNCOMPLICATED tx
Uncomplicated: short course (103 days) of topical (vaginal) azole e.g. clotrimazole (OTC)
Vulvovaginal Candidaisis: COMPLICATED definition and tx
def: Recurrent (> or =4 episodes in 1 yr), severe, non-albicans, patient has uncontrolled DM or immune compromise
-tx w/longer duration (7-14 d) topical azole or oral fluconazole (Diflucan)
IF NON-ALBICANS, AVOID FLUCONAZOLE-pick a different azole
Vulvovaginal Candidiasis: tx of male partner
male partner DOESN’T NEED TX
UNLESS HE HAS BALANTIS (inflammation of the skin covering the glans of the penis)
Vulvovaginal candidiasis: pregnant patients tx
ONLY use TOPICAL txs in pregnant pts
What do you do if a patient has recurrent or difficult to tx yeast infections?
evaluate for DM, HIV
Bacterial Vaginosis: an STD?
NOT an STD
Vulvovaginal Candidiasis: an STD?
NOT an STD
Bacterial Vaginosis causative organism/background
results from disruption of usual, "healthy" vaginal microflora (Lactobacillus sp)-allows overgrowth of bacturea cause is (U) polymicrobial, often a/w Gardnerella vaginalis & Mobiluncus sp (gram variable anaerobes)
Bacterial Vaginosis: Clinical Presentation
vaginal irritation, thin white or gray discharge w/strong fishy odor
Bacterial Vaginosis: Risk factors
(although NOT an STD),
- New or multiple sex partners
- douche
- can affect women that are NOT sexually active
Bacterial vaginosis diagnosis (clinical criteria)
Clinical criteria (Amsel’s criteria) at least 3 of 4 present
- Thin white homogenous discharge
- Clue cells on microscopy
- Vaginal fluid pH>4.5
- Release of fishy odor when adding KOH solution (+whiff test)
Bacterial vaginosis: lab test
best LAB test is Gram stain-shows anaerobes known to cause BV & lack of Lactobacilli
-Gold Standard but NOT generally used clinically
Bacterial Vaginosis: tx
treat ALL PATIENTS WITH SXS
Metronidazole (Flagyl) orally for 7 days
-avoid EtOH while taking metronidazole
Metronidazole gel intravaginally for 5 dyas
Clindamycin orally or intravaginally
PREGO PTs: USE ORAL MEDS [just incase they have an infection higher up & to avoid premature birth]
Bacterial Vaginosis: male partner tx
male partner DOES NOT need tx
Bacterial Vaginosis: complications
- increases risk of acquiring & transmitting HIV
- increases risk of acquiring herpes, gonorrhea (GC) & chlamydia
- a/w PID (but BV is not believed to he a causative factor)
Trichomoniasis: causative organism & description
Trichomonas vaginalis: single celled protozoan parasite
Trichomoniasis: how common is this?
common (most common NON-VIRAL)
Trichomoniasis: sxs appear when
1-4 weeks after exposure
men (U) ASYMPTOMATIC: sxs<10% of cases [male sx: clear or mucopururent urethral dc &/or dysuria]