STD Flashcards
What is the pathophysiology of HIV and AIDS?
1) virus invades body
2) virus attaches to surface of CD4 T lymphocytes
3) invades inside the cell and gets the DNA messed up with the virus’s RNA via reverse transcriptase
4) during the lytic stage, the RNA destroys the CD4 in the process
therefore if CD4 is LOW = BAD
Why is important to keep tabs on HIV patients?
patients die from secondary causes (ie. infxns of other organs of the body) SO providers need to keep a close eye on their health AND CD4 count
Who are at high risk for HIV exposure?
MSM
IV drug use
How do you dx HIV?
ELISA and Western blot
What is the ideal CD4 count?
> 500
What are the clinical features of HIV?
1) primary infxn - sx are like cold
2) asymptomatic - “gets better from cold” - CD4 will be normal
3) symptomatic - fungal infxn, hair leukoplakia, trich infxn in females
4) AIDS - CD4
20yo male hx of HIV presents with F/N/coughing, no vomiting for the past 2days. Patient tried Peptobismol and tylenol with no relief. Patient denies drug use, smoke, drinking. Patient denies recent surgeries. Patient states he had a CD4 of 250 at his last PCP appt.
What dz could this patient be vulnerable for?
lungs - pneumonia, TB skin - kaposi sarcoma, herpes zoster males - proctitis females - PID HIV wasting syndrome - w/ F/N/V