Statistics and Data Analysis Flashcards

1
Q

What is analytical biochemistry

A
  • The study of biochemical components found in a cell or other biological sample
  • Use a broad range of techniques for separation, identification, quantification and functional characterisation of biological molecules
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2
Q

What are the requirements for analytical testing

A
  • Screening (detection of disease)
  • Diagnosis (Confirmation/rejection)
  • Prognosis (Likely outcome of disease)
  • Monitoring ( History / Response to treatment
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3
Q

What are the commonly used techniques in analytical biochemistry ?

A
  • Chromatography
  • Electrophoresis
  • Spectroscopy
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4
Q

What is Chromatography

A
  • Separates components of a mixture based on their chemical properties separates and identifies components of a complex mixture
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5
Q

Examples of Chromatography

A
  • HPLC, GC, TLC
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6
Q

What is Electrophoresis?

A
  • Separates charged molecules based on their size and charge
  • Separates and identify proteins, DNA and RNA
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7
Q

What is Spectroscopy?

A
  • Uses the interaction of light with matter to study the properties of biological molecules
  • Used to study the structure and function of proteins, nucleic acids, and other biological molecules
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8
Q

What is clinical biochemistry ?

A
  • Generally concerned with the analysis of bodily fluids for diagnostic and therapeutic purposes
  • An applied form of biochemistry
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9
Q

What is Clinical biochemistry also known as

A
  • Clinical chemistry, chemical pathology, or medical biochemistry
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10
Q

Name some categories of test of Clinical Biochemistry

A
  • General or routine chemistry
  • Special chemistry
  • Clinical endocrinology
  • Toxicology
  • Therapeutic Drug Monitoring
  • Urinalysis
  • Faecal analysis
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11
Q

What is near patient testing?

A
  • May also be called point-of-care testing
  • Performed near or at the site of patient - the result may change care pathway for the patient
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12
Q

What are the advantage patient testing

A
  • Generally faster than traditional lab testing
  • May require smaller sample
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13
Q

What is the disadvantage of patient testing

A
  • Maybe less accurate - clinical staff
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14
Q

What are the applications of Near Patient Testing

A
  • Diagnosis of infectious diseases
  • Monitoring of chronic diseases
  • Detection of drug abuse
  • Guide to other problems
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15
Q

Name Near Patient testing devices

A
  • Blood glucose meters
    -Pregnancy tests
  • Rapid strep test
  • Covid test
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16
Q
A