Statistics and Data Analysis Flashcards
1
Q
What is analytical biochemistry
A
- The study of biochemical components found in a cell or other biological sample
- Use a broad range of techniques for separation, identification, quantification and functional characterisation of biological molecules
2
Q
What are the requirements for analytical testing
A
- Screening (detection of disease)
- Diagnosis (Confirmation/rejection)
- Prognosis (Likely outcome of disease)
- Monitoring ( History / Response to treatment
3
Q
What are the commonly used techniques in analytical biochemistry ?
A
- Chromatography
- Electrophoresis
- Spectroscopy
4
Q
What is Chromatography
A
- Separates components of a mixture based on their chemical properties separates and identifies components of a complex mixture
5
Q
Examples of Chromatography
A
- HPLC, GC, TLC
6
Q
What is Electrophoresis?
A
- Separates charged molecules based on their size and charge
- Separates and identify proteins, DNA and RNA
7
Q
What is Spectroscopy?
A
- Uses the interaction of light with matter to study the properties of biological molecules
- Used to study the structure and function of proteins, nucleic acids, and other biological molecules
8
Q
What is clinical biochemistry ?
A
- Generally concerned with the analysis of bodily fluids for diagnostic and therapeutic purposes
- An applied form of biochemistry
9
Q
What is Clinical biochemistry also known as
A
- Clinical chemistry, chemical pathology, or medical biochemistry
10
Q
Name some categories of test of Clinical Biochemistry
A
- General or routine chemistry
- Special chemistry
- Clinical endocrinology
- Toxicology
- Therapeutic Drug Monitoring
- Urinalysis
- Faecal analysis
11
Q
What is near patient testing?
A
- May also be called point-of-care testing
- Performed near or at the site of patient - the result may change care pathway for the patient
12
Q
What are the advantage patient testing
A
- Generally faster than traditional lab testing
- May require smaller sample
13
Q
What is the disadvantage of patient testing
A
- Maybe less accurate - clinical staff
14
Q
What are the applications of Near Patient Testing
A
- Diagnosis of infectious diseases
- Monitoring of chronic diseases
- Detection of drug abuse
- Guide to other problems
15
Q
Name Near Patient testing devices
A
- Blood glucose meters
-Pregnancy tests - Rapid strep test
- Covid test