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Microbiology ME3(Staphylococcus aureus) > staph.aurues > Flashcards

staph.aurues Flashcards

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1
Q

Structure use by Staplycoccus to evade phagocystosis?

A

Protein A

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2
Q

A super- antigen capable of activating large number of T cells.

A

toxin -mediated

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3
Q

virulence factor produce by S. aureus that increased permeability to cations and osmotic instability

A

gamma toxin and P-V leukocidin

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4
Q

Genus Staphylococcus is known in converting fibrinogen to insoluble fibrin . What enzyme is responsible for this?

A

coagulase

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5
Q

an important virulence factor in MRSA

A

Panton-valenttine leukocidin

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6
Q

capsule of S. pyogenes is made up of ?

A

hyaluronic acid

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7
Q

resistance of S. aureus to the antibiotic Methicillin can be due to 3 mechanism?

A

a. production of penicillin-binding protein 2a (PBP2a)encoded by mecA gene
b. production of beta lactamases
c. production of modified intrinsic PBPs

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8
Q

Tinidora 26 F, a sex worker was experiencing pain in her lower pelvic for several weeks after engaging in a romantic affair. She was diagnose to have a UTI and was prescribed with antibiotics.What species of Staphylococcus responsible for this?

A

Staphylococcus saprophyticus

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9
Q

Strains of S aureus produce this virulence factor that catalyzes the hydrolysis of membrane phospholipids

A

beta toxin

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10
Q

morphology of genus Staphylococcus

A 
cluster
spherical shape
gram(+)
\+/- catalase
facultative anerobes
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11
Q

Believed to be an important mediator of tissue damage in Staphylococcus disease

A

alpha toxin

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12
Q

Enzyme that allows the growth of Staphylococcus on the skin surface and cutaneous oil glands

A

lipases

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13
Q

Staphylococcus infection characterized as a bubble-like swellings that can break and peel away; common in newborn

A

impetigo

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14
Q

Exfoliative intoxication of S. aureus can lead to what disease?

A

Ritter’s disease

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15
Q

A characteristic of S. aureus upon culturing on a blood agar?

A

beta- hemolysis

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16
Q

Julius 21M, was rushed to the emergency room because of severe bowel loss after eating contaminated food in a fancy restaurant.(VS) BP: 70/60; RR:25; Tem: 39.7C HR: 50. There is also noted rashes on skin. Culture of stool revealed strain of Staphylococcus.What condition was manifested by the patient?

A

`Toxic shock syndrome toxin

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17
Q

the only specie under the genus Stomatococcus that is commensal and reside in the oropharynx and upper respiratory tract

A

Stomatococcus mucilaginosus

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18
Q

Virulence factor produce by S. pyogones that cause the rashes in scarlet fever?

A

Erythrogenic toxins

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19
Q

most important measure in preventing nosocomial infections|?

A

hand antisepsis

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20
Q

most frequenlty isolated Staphylococcus spp. that colonize moist body areas such as axilla, inguinal and perianal areas?

A

S. epidermidis

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21
Q

Staphtlococcal enzyme that enabling the bacteria to spread between cells

A

hyaluronidase

22
Q

True or False

Staphylococcus aureus is a spore-forming bacteria.

A

false( non-spore forming)

23
Q

Strains of Staphylococcus is known to be very resistant to many chemical agents and heat. They resist the action of some potent antiseptic and bacteriocidal agent(hydrogen peroxide). What is responsible for this resistant of S.?

A

catalase

24
Q

structural component of S. that provides anchor for the cellulsr biosynthetic and respiratory enzyme?

A

cytoplasmic membrane

25
Q

first line antibiotics used for the treatment of Toxic Shock syndrome

A

oxacillin(methicillin)

1st gen. cephalosporins(cefazolin, cephalotin)

26
Q

Large and deep lesion created by aggregation and interconnection of cluster of furuncle

A

carbuncle

27
Q

A acute superficial cellulitis of the skin with lymphatic involvement cause by S. pyogenes?

A

erysipelas

28
Q

MIckey 21M , mountainer is complaining of diffulty in swallowing, and erythematous rash all over his body several days ago.Upon physical examination a “strawberry tounge was noted”. Culture was done and postive for S. pyogenes. According to lancefield classification what group this organism belongs.

A

Group A

29
Q

Antibiotic of Choice for MRSA

A

vancomycin

30
Q

Major virulence factor of S. pyogenes that contributes to resistance to phagocytosis.

A

M protein

31
Q

true or false

Genus under Peptococcus are faculatative aerobic gram negative cocci?

A

false(obligate anaerobic gram positive cocci)

32
Q

One specie under Staphylococcus that causes urinary tract infection in catheterized patients.

A

S. epidermidis

33
Q

Toxic shock syndrome toxin 1 was formerly called as?

A

pyrogenic exotoxin C and enterotoxin F

34
Q

Toxins produce by Staphylococcus that are found in contaminated milk products

A

Enterotoxin C and D

35
Q

one distinct characteristic of Staphylococcus is to dissolves fibrin threads. What enzyme is responsible?

A

staphylokinase( fibrinolysisn)

36
Q

Maria venasuraj 23F supermodel was complaining with abdominal pain for several weeks. She consulted a doctor and was diagnose to have a Staphylococcal pseudomembranous enterocolitis. Pathogenic agents under this genus produce several toxins.What toxin was responsible for her condition?

A

Enterotoxin B

37
Q

Mechanism behind the resistance of S. aureus to penicillin group of antibiotics?

A

beta- lactamase production(plasmid mediated)

38
Q

Structure use by Staphylococcus for protection from phagocytosis and chemotaxis of polymorphonuclear cells

A

capsule

39
Q

A six gene sequences located on Staphylococcal casette chromosome mec.

A

mecA gene

40
Q

An important structure of S. that catalyze construction of peptidoglycan layer and main target for several antibiotics

A

penicillin-binding proteins

41
Q

toxin produce by genus Stahylococcus that act as surfactant disrupting membranes by means of a detergent-like action

A

delta toxin

42
Q

Antimicrobial susceptibility and resistance of MRSA due to mecA can be detected via?

A

cefoxitin disk diffusion or dilution methods(acc. to CLSI)

43
Q

Post- Streptococcal disease:

non suppurative sequelae is consist of?

A

Rhematic fever; carditis;glomerulonephritis

44
Q

systemic effect of Toxic shock syndrome toxin 1

A

hypovolemia

45
Q

toxins responsible for Staphylococcal scalded skin syndrome usually sen in infants and children

A

exfoliative A and B

46
Q

True or false

Genus under Streptococcus are gram positive, catalase negative and facultative anaerobes

A

true

47
Q

In Lancefield classification of Streptococcus, species that are found in human urogenital tract belongs to what group?

A

Group D

48
Q

Staphylococcal food poisoning (enterotoxicosis) may lead to__________ if toxi are not removed.

A

megacolon

49
Q

2 species of Micrococcus

A

M. luteus; M. lyla

50
Q

Survival of S. pyogenes intracellulary as a result of damaging the membranes of RBC, myocardial cells and PMNs is mediated by what thiol-activated toxin?

A

Streptolysis O

51
Q

They bind the bacteria to tissues and foreign bodies that is important for the survival of avirulent coagulase-negative sthaphylococci

A

slime layer/biofilm

Microbiology ME3(Staphylococcus aureus) (1 decks)

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