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Surgical Pathology > Stains > Flashcards

Stains Flashcards

1
Q

AFB (TBC)

A

Acid-fast bacilli (TB or M. avium-intercellulare)

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2
Q

Fite stain

A

Acid-fast bacilli, especially M. leprae

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3
Q

Congo red

A

Amyloid

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4
Q

Dieterle

A

Spirochetes

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5
Q

VVG

A

Elastin

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6
Q

Brown Benn

A

Bacteria

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7
Q

Prussian blue/Fe

A

Iron stores (hemachromatosis)

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8
Q

PASF

A

Fungus (periodic acid-Schiff with fungal control)

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9
Q

PASFD

A

Candida on esophageal biopsies and fungal infections on skin biopsies (PAS with diastase digestion and fungal control)

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10
Q

GMS

A

Fungi and pneumocystis (Grocott methenamine silver)

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11
Q

Masson

A

Collagen

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12
Q

Von Kossa

A

Calcium

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13
Q

Warthin-Starry

A

Spirochetes

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14
Q

ORO

A

Lipids on frozen sections (oil red O)

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15
Q

ACHE

A

Hirschprung’s disease (acetylcholinesterase)

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16
Q

CMV

A

Cytomegalovirus (immunosuppressed patients)

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17
Q

ADV

A

Adenovirus (small and large bowel in immunosuppressed pediatric patients)

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18
Q

HP

A

Helicobacter pylori in all gastric antral biopsies

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19
Q

Cytokeratin

A

Sentinel lymph nodes in breast cancer

20
Q

EBNA 2/LMP-1

A

Ebstein-Barr virus on EBV-related tumors and some immunosuppressed patients

21
Q

Calretinin

A

Hirschsprung’s disease

22
Q

ER/PR, Her 2 neu, EGFR

A

Prognostic indicators for breast cancer (ER/PR = estrogen/progesterone receptor, EGFR = epidermal growth factor receptor)

23
Q

CA 125

A

Ovarian tumor marker

24
Q

GFAP, HAM 356/CD68, Ki-67

A

Brain tumors and lymphomas (GFAP = glial fibrillary acidic protein)

25
Q

PSA

A

Prostatic differentiation (prostate-specific antigen)

26
Q

S100

A

Neural differentiation

27
Q

Mart-1

A

Melanoma

28
Q

Synaptophysin and Chromagranin

A

Neuroendocrine differentiation

29
Q

SMA and desmin

A

Muscle differentiation (SMA = smooth muscle actin)

30
Q

TTF-1

A

Lung adenocarcinoma and/or thyroid origin (thyroid transcription factor 1)

31
Q

CD10, Pax2, and RCC

A

Renal cell carcinoma

32
Q

PLAP

A

Germ cell differentiation (placental alkaline phosphatase)

33
Q

Mammoglobin

A

Breast tissue

34
Q

HepPar-1

A

Liver

35
Q

CK 903 (34Beta E12) , CK5/6, and p63

A

Basal cell markers in breast and prostate cancers

36
Q

P504s

A

Prostate cancer glands

37
Q

p16

A

Cervical cancers/dysplasias

38
Q

p53

A

Over-expression of tumor suppression gene (prognostic marker)

39
Q

CD45

A

Leukocyte common antigen (LCA) for lymphoid differentiation

40
Q

CD3, CD4, CD8, CD2, CD5, CD7

A

T cell markers

41
Q

CD 20

A

B cells, treatment decisions

42
Q

CD 117

A

Diagnosis of gastrointestinal stromal tumors, myeloid differentiation

43
Q

CD 138

A

Plasma cell differentiation

44
Q

CD 31, CD 34

A

Endothelial cells and CD34 blasts

45
Q

CD10 and bcl-6

A

Lymphoid germinal cell markers

46
Q

CD15

A

Myeloid cells and Hodgkin cells

47
Q

CDX2

A

Colon and some GI tumors

Surgical Pathology (6 decks)

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