SSSS

Question 1

Etiology of SSSS

Answer 1

Staph aureus exfoliative toxin (ETA, ETB- most common, and ETD) which targets desmoglein 1 (get sterile blisters within stratum granulosum). Bullous impetigo is the localized form

Question 2

Initial site of involvement in kids vs. infants

Answer 2

In kids, face

In infants, diaper area