SQUAMOUS CA Flashcards

1
Q

Non-healing oral ulcers warrant biopsy to exclude

A

squamous cell carcinoma (SCC)

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2
Q

is the seventh most common malignancy

A

Bladder cancer

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3
Q

with 90% being transitional cell
carcinomas

A

Bladder cancer

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4
Q

Smoking is the
most common association.

A

Bladder cancer

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5
Q

The most common cervical cancer is

A

squamous cell carcinoma (SCC)

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6
Q

are responsible
for around 70% of invasive cervical cancers

A

HPV 16 and 18

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7
Q

Low-grade squamous intraepithelial lesions (LSILs) represent an

A

acute HPV infection

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8
Q

Persistent infection with an
oncogenic HPV type causes

A

precancerous changes

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9
Q

cervix (benefits of use outweigh the risk with a low- or high-grade squamous intraepithelial
lesion)

A

CHC and cancer

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10
Q

80% due to squamous cell carcinoma

A

Cervical cancer

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11
Q

important not to misdiagnose malignant ulcers, including ‘Marjolin ulcer’, which is
a

A

squamous cell carcinoma (SCC)

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12
Q

The three
main skin cancers are the non-melanocytic skin cancers

A

(BCC) and
(SCC)—and melanoma

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13
Q

is the second most common type of skin cancer.

A

squamous cell carcinoma (SCC)

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14
Q

It is found on sun-exposed areas, especially
in fair-skinned people.

A

squamous cell carcinoma (SCC)

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15
Q

arise in premalignant areas solar keratoses, burns,
chronic ulcers

A

squamous cell carcinoma (SCC)

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16
Q

Keratoacanthoma is considered a variant

A

squamous cell carcinoma (SCC)

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17
Q

Surrounding erythema
The hard nodules may ulcerate

A

squamous cell carcinoma (SCC)

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18
Q

Ulcers have a characteristic everted edge

A

squamous cell carcinoma (SCC)

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19
Q

of ear, lip, oral cavity, tongue and genitalia are serious

A

squamous cell carcinoma (SCC)

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20
Q

Early excision of tumours <1 cm

A

squamous cell carcinoma (SCC)

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21
Q

Referral for specialized surgery and/or radiotherapy if large, in difficult site or
lymphadenopathy

A

squamous cell carcinoma (SCC)

22
Q

Surgery is the treatment of choice for most tumours

A

squamous cell carcinoma (SCC)

23
Q

is an optional treatment in a biopsy-proven tumour

A

Radiotherapy

24
Q

Most common skin cancer

A

Basal cell carcinoma

25
Mostly on sun-exposed areas: face (mainly), neck, upper trunk, limbs (10%)
Basal cell carcinoma
26
May ulcerate easily = ‘rodent ulcer’
Basal cell carcinoma
27
Has various forms: nodular, pigmented, ulcerated, etc
Basal cell carcinoma
28
pearliness and distinct margin
Basal cell carcinoma
29
Metastases very rare
Basal cell carcinoma
30
Simple elliptical excision (3–4 mm margin) is best.
Basal cell carcinoma
31
Mohs micrographic surgery—a form of surgical treatment
Basal cell carcinoma
32
Imiquimod 5% daily 5 times
Basal cell carcinoma
33
Photodynamic therapy—response rate is about 80%
Basal cell carcinoma
34
Cryotherapy is suitable
Basal cell carcinoma
35
arise in pre-existing naevi, many of which are dysplastic
one-third of all melanomas
36
The most important factor in management is early detection
Malignant melanoma
37
Currently the greatest rate of increase is in men >55 years.
Malignant melanoma
38
are markers of an increased risk of melanoma
Dysplastic melanocytic naevi
39
Most common on trunk
Dysplastic melanocytic naevi
40
Irregular and ill-defined border
Dysplastic melanocytic naevi
41
family history of melanoma. lifetime risk of melanoma may approach 100%
Dysplastic naevus syndrome
42
6-monthly review for 2 years, yearly thereafter
Dysplastic naevus syndrome
43
3 monthly review if family history of melanoma
Dysplastic naevus syndrome
44
Any suspicious lesions should be excised for histological examination.
Dysplastic naevus syndrome
45
An irregular border or margin is suggestive of the tumour
Melanoma
46
Full skin examination every 6 to 12 months by health professional
Melanoma
47
Can occur anywhere —more common: lower limbs in women, upper back in men
Melanoma
48
The sign of major importance is a recent change in a mole
Melanoma
49
change in size—shape, colour—surface border
Melanoma
50
New or changing lesion
Red flag for melanoma
51
Rapidly growing nodule of any colour
Red flag for melanoma
52