SQUAMOUS CA Flashcards

1
Q

Non-healing oral ulcers warrant biopsy to exclude

A

squamous cell carcinoma (SCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

is the seventh most common malignancy

A

Bladder cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

with 90% being transitional cell
carcinomas

A

Bladder cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Smoking is the
most common association.

A

Bladder cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

The most common cervical cancer is

A

squamous cell carcinoma (SCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

are responsible
for around 70% of invasive cervical cancers

A

HPV 16 and 18

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Low-grade squamous intraepithelial lesions (LSILs) represent an

A

acute HPV infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Persistent infection with an
oncogenic HPV type causes

A

precancerous changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

cervix (benefits of use outweigh the risk with a low- or high-grade squamous intraepithelial
lesion)

A

CHC and cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

80% due to squamous cell carcinoma

A

Cervical cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

important not to misdiagnose malignant ulcers, including ‘Marjolin ulcer’, which is
a

A

squamous cell carcinoma (SCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The three
main skin cancers are the non-melanocytic skin cancers

A

(BCC) and
(SCC)—and melanoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

is the second most common type of skin cancer.

A

squamous cell carcinoma (SCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

It is found on sun-exposed areas, especially
in fair-skinned people.

A

squamous cell carcinoma (SCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

arise in premalignant areas solar keratoses, burns,
chronic ulcers

A

squamous cell carcinoma (SCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Keratoacanthoma is considered a variant

A

squamous cell carcinoma (SCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Surrounding erythema
The hard nodules may ulcerate

A

squamous cell carcinoma (SCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Ulcers have a characteristic everted edge

A

squamous cell carcinoma (SCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

of ear, lip, oral cavity, tongue and genitalia are serious

A

squamous cell carcinoma (SCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Early excision of tumours <1 cm

A

squamous cell carcinoma (SCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Referral for specialized surgery and/or radiotherapy if large, in difficult site or
lymphadenopathy

A

squamous cell carcinoma (SCC)

22
Q

Surgery is the treatment of choice for most tumours

A

squamous cell carcinoma (SCC)

23
Q

is an optional treatment in a biopsy-proven tumour

A

Radiotherapy

24
Q

Most common skin cancer

A

Basal cell carcinoma

25
Q

Mostly on sun-exposed areas: face (mainly), neck, upper trunk, limbs (10%)

A

Basal cell carcinoma

26
Q

May ulcerate easily = ‘rodent ulcer’

A

Basal cell carcinoma

27
Q

Has various forms: nodular, pigmented, ulcerated, etc

A

Basal cell carcinoma

28
Q

pearliness and distinct margin

A

Basal cell carcinoma

29
Q

Metastases very rare

A

Basal cell carcinoma

30
Q

Simple elliptical excision (3–4 mm margin) is best.

A

Basal cell carcinoma

31
Q

Mohs micrographic surgery—a form of surgical treatment

A

Basal cell carcinoma

32
Q

Imiquimod 5% daily 5 times

A

Basal cell carcinoma

33
Q

Photodynamic therapy—response rate is about 80%

A

Basal cell carcinoma

34
Q

Cryotherapy is suitable

A

Basal cell carcinoma

35
Q

arise in pre-existing naevi, many of which are dysplastic

A

one-third of all melanomas

36
Q

The most important factor in management is early detection

A

Malignant melanoma

37
Q

Currently the greatest rate of increase is in men >55 years.

A

Malignant melanoma

38
Q

are markers of an increased risk of
melanoma

A

Dysplastic melanocytic naevi

39
Q

Most common on trunk

A

Dysplastic melanocytic naevi

40
Q

Irregular and ill-defined border

A

Dysplastic melanocytic naevi

41
Q

family history of melanoma. lifetime
risk of melanoma may approach 100%

A

Dysplastic naevus syndrome

42
Q

6-monthly review for 2 years, yearly thereafter

A

Dysplastic naevus syndrome

43
Q

3 monthly review if family history of melanoma

A

Dysplastic naevus syndrome

44
Q

Any suspicious lesions should be excised for histological examination.

A

Dysplastic naevus syndrome

45
Q

An irregular border or margin is suggestive of the tumour

A

Melanoma

46
Q

Full skin examination every 6 to 12 months by health professional

A

Melanoma

47
Q

Can occur anywhere —more common:
lower limbs in women, upper back in men

A

Melanoma

48
Q

The sign of major importance is a recent change in a mole

A

Melanoma

49
Q

change in size—shape, colour—surface
border

A

Melanoma

50
Q

New or changing lesion

A

Red flag for melanoma

51
Q

Rapidly growing nodule of any colour

A

Red flag for melanoma

52
Q
A