Spring Top 300 Drugs Flashcards
Which of the following is the pharmacological class for hydroxyzine?
antihistamine
Which of the following is an FDA-approved indication for clobetasol?
Plaque psoriasis
Does alendronate require dose adjustment for hepatic impairment?
No
Which is a pharmacologic class of adapalene?
Retinoid
One of the FDA-approved indications for meclizine is
Vertigo
What is the brand name of dulaglutide?
Trulicity
What is the mechanism of action for fexofenadine?
Selective H-1 Receptor Antagonist
The mechanism of action of clindamycin topical is to inhibit bacterial protein synthesis by binding to which of the following ribosomal subunits?
50S
Which of the following is a major adverse drug reaction for ibandronate?
Indigestion
Which of the following is a major adverse drug reaction of cetirizine?
Drowsiness
By inhibiting _____, amiodarone may increase the risk of hypoglycemia when combined with glimepiride.
CYP2C9
What is the mechanism of action for linagliptin?
Prolongs incretin levels
Metformin works by
Reducing hepatic glucose production
Which of the following is a major adverse drug reaction for glipizide?
Disulfiram reaction
Which of the following is a major adverse drug reaction of liraglutide?
Renal failure
Which is the pharmacologic class of insulin glargine?
Long-acting insulin
What is the brand name of insulin lispro?
Humalog
What is the brand name of insulin aspart
Novolog
What is the generic name of Afrezza?
Inhaled insulin
What is the generic name of Apidra?
Insulin glulisine
Which of the following is the pharmacological class for repaglinide?
Meglitinide
Which one of the following is LEAST likely to be involved in CYP450 mediated drug-drug interactions?
Dexlansoprazole
The brand name for rosiglitazone is
Avandia
Which is a pharmacologic class of dicyclomine?
Antimuscarinic
Which of the following is an FDA-approved indication for dutasteride?
Benign Prostatic Hyperplasia
What is the brand name of saxagliptin?
Onlgyza
What is the mechanism of action for famotidine?
H2 antagonism
Pioglitazone works by
Increasing insulin sensitivity
Which of the following is a major adverse drug reaction for sitagliptin?
Rhabdomyolysis
Is renal dosing adjustment required for canagliflozin?
Yes
Which of the following is the pharmacological class for phenazopyridine?
analgesic
Which of the following is an FDA-approved indication for darifenacin?
Overactive bladder
The brand name for pentosan is
Elmiron
Which is a pharmacologic class of polyethylene glycol?
Hyperosmotic laxative
Which of the following is an FDA-approved indication for omeprazole?
Erosive esophagitis
What is the brand name of rabeprazole?
AcipHex
What is the mechanism of action for oxybutynin?
Muscarinic Receptor Antagonist
Lubiprostone works by
Activating chloride channels
Does ranitidine require dose adjustment for renal dysfunction?
Yes
A patient taking metoclopramide with Phenergan would be at greater risk of ___________ compared to a patient taking either drug alone.
Tardive dyskinesia
Which of the following is the pharmacological class for tolterodine
Antimuscarinic
Which one of the following medications is LEAST likely to decrease tamoxifen activation?
Effexor
The brand name for ethinyl estradiol/etonogestrel is
NuvaRing
Which is a pharmacologic class of anastrozole?
Aromatase Inhibitor
Which of the following is an FDA-approved indication for darbepoetin?
Anemia of CKD
Does epoetin require hepatic dose adjustment?
No
Cyanocobalamin works by acting as a cofactor for ________ synthesis.
Amino acid
Tamsulosin works through ___________ of _____ receptors.
Inhibition; alpha-1
Which of the following is an adverse drug reaction for estradiol?
Venous thromboembolism
Which of the following is a major adverse drug reaction of epinephrine?
Pulmonary edema
Which of the following is the FDA-approved indication for folic acid?
Megaloblastic anemia
Which of the following is a major adverse effect of intranasal fluticasone?
Glaucoma
The brand name for fluocinonide is __________.
Vanos
Does methylprednisolone require renal dose adjustment?
No
One of the FDA-approved indications for topical hydrocortisone is __________.
Atopic Dermatitis
What is the mechanism of action for medroxyprogesterone?
It transforms proliferative into secretory endometrium
What is the pharmacologic class of Aranelle?
Triphasic oral contraceptive
The presumed mechanism of action of mometasone is induction of what?
Phospholipase A2 inhibitory proteins
Which of the following is a major adverse reaction of levothyroxine?
Hyperthyroidism
Drospirenone/ethinylestradiol is also known by which brand name?
Yasmin
The dose of Cialis should be reduced when administered concurrently with:
Biaxin
Triamcinolone Nasal has an FDA indication for which of the following disease states?
Allergic Rhinitis
Which of the following is the pharmacological class of prednisone?
Adrenal corticosteroid
Which of the following describes the mechanism of action of raloxifene?
Selectively binds to estrogen receptors
An adverse effect of Armour Thyroid is the aggravation of preexisting what type of disease?
Cardiovascular
Which of the following is a brand name for the pertussis vaccine?
Boostrix
Which of the following is/are involved in the mechanism of action of etanercept?
TNF alpha
What is the pharmacological class of sildenafil?
Pulmonary hypertension agent
Is hepatic dose adjustment required for testosterone?
No
Which of the following is an adverse drug reaction to the pneumococcal vaccine?
Myalgia
What is the brand name for Baclofen?
Lioresal
The combined use of apomorphine and Zofran is contraindicated due to:
Additive hypotension
Which of the following is an FDA approved indication for carbamazepine?
Trigeminal neuralgia
Inhibition of phosphodiesterase type 5 to increase the amount of cyclic GMP is the mechanism of action of which drug?
Vardenafil
Which of the following is a major adverse effect of promethazine?
Xerostomia
Is renal dose adjustment recommended for tizanidine?
Yes
Nabumetone belongs to which pharmacological class?
NSAID
Which of the following is an FDA approved indication for methocarbamol?
Musculoskeletal spasm
What is the mechanism of action of carbidopa in carbidopa/levodopa?
It inhibits decarboxylation of levodopa to allow more to reach the CNS
Which of the following is a major adverse drug reaction of cyclobenzaprine?
Drowsiness
Which of the following is the proposed mechanism of action for clobazam?
Potentiation of neurotransmission from binding at the GABA receptor
Which of the following is an FDA-approved indication for divalproex?
Migraine prophylaxis
Which of the following is the brand name for donepezil?
Aricept
Which of the following is a major adverse drug reaction to lamotrigine?
Diplopia
Is renal dose adjustment recommended for oxcarbazepine?
Yes
A proposed mechanism of action of eletriptan is that it produces vasoconstriction through the activation of which intracranial receptors?
Serotonin
Which of the following types of seizures is an FDA-approved indication for lacosamide?
Partial onset
What is the generic name for Namenda?
Memantine
Patient TF has been started on phenytoin for treatment of epilepsy. This is the patient’s first treatment for epilepsy and they have only been on phenytoin for 2 weeks and are still having seizures daily. Patient is also currently on apixaban for stroke prophylaxis. A consult was placed to have pharmacy look at the patient’s medications and make their recommendation. Which of the following is the BEST answer regarding modifying this patient’s medication therapy?
Change the patient’s epilepsy medication, potentially to Keppra
Which of the following is a major adverse drug reaction to sumatriptan?
Cardiac dysrhythmia
Cyclosporine inhibits the production of which interleukin?
2
Which of the following is an FDA-approved indication for loteprednol?
Postoperative inflammation
Is renal dose adjustment recommended for topiramate?
Yes
Which of the following is the generic name for lumigan?
Bimatoprost
Which of the following is a major adverse reaction to celecoxib?
Hypertension
What does moxifloxacin ophthalmic inhibit as part of its MOA?
Topoisomerase II
Which of the following is the FDA-approved indication for olopatadine?
Allergic Conjunctivitis
Which of the following is the pharmacological drug class for travoprost?
Prostaglandin
What is the brand name of latanoprost?
Xalatan
The analgesic effects of which one of the following will be reduced if taken together with a strong CYP2D6 inhibitor?
Codeine/APAP
Which of the following is a major adverse drug reaction for diclofenac?
Acute renal failure
What is the brand name for etodolac?
Lodine
Which of the following is an FDA-approved indication for ibuprofen?
Fever
Which of the following vaccines should be avoided in a patient being treated with a TNF-alpha inhibitor?
Varivax
Which of the following does Meloxicam inhibit as part of its mechanism of action?
COX-1 and COX-2
Which of the following is a major adverse drug reaction of hydrocodone?
Constipation
What is the pharmacological class of the lidocaine topical patch?
Local anesthetic
Is hepatic dose adjustment required for methadone?
No
Which of the following is an FDA-approved indication for Kadian?
Moderate to severe chronic pain
What is the brand name for naproxen?
Naprosyn
What is the pharmacological class of Tramadol?
Opioid
What is the generic name for Abilify?
Aripiprazole
The mechanism of action for benztropine involves inhibiting reuptake and storage of what?
Dopamine
Which of the following is an FDA-approved indication of prochlorperazine?
Anxiety
Which of the following is a major adverse drug reaction to Lithium?
Hypothyroidism
Are there hepatic dose limitations for citalopram?
Yes
What is the brand name for buspirone?
Buspar
Which of the following is an FDA-approved indication for lurasidone?
Schizophrenia
Desvenlafaxine is a potent reuptake inhibitor of what?
Norepinephrine
Metabolic clearance of which of the following will be affected by smoking tobacco?
Zyprexa
Which one of the following is LEAST likely to be involved in CYP450 mediated drug-drug interactions?
Ziprasidone
What is the generic name for Harvix?
Hepatitis A Vaccine
Which of the following is an FDA-approved indication for tacrolimus?
Liver transplant rejection
Which of the following is a major adverse drug reaction to the influenza vaccine?
Which of the following is a major adverse drug reaction to the influenza vaccine?
Risperidone is a potent antagonist of what?
Serotonin
Which of the following is an approved FDA indication of Recombivax HB?
Prevention of Hepatitis B infection
Is renal dosage adjustment required for quetiapine?
No
Which of the following is the pharmacological class for the HPV vaccine?
Vaccine, Inactivated, Viral
Which of the following is a brand name for Haemophilus Influenzae Type B Vaccine?
Hiberix
Which of the following is an approved FDA-indication of potassium iodide?
Prevention of thyroid dysfunction due to radiation exposure
