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Spring Top 300 drugs > Spring Top 300 Drugs > Flashcards

Spring Top 300 Drugs Flashcards

1
Q

Which of the following is the pharmacological class for hydroxyzine?

A

antihistamine

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2
Q

Which of the following is an FDA-approved indication for clobetasol?

A

Plaque psoriasis

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3
Q

Does alendronate require dose adjustment for hepatic impairment?

A

No

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4
Q

Which is a pharmacologic class of adapalene?

A

Retinoid

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5
Q

One of the FDA-approved indications for meclizine is

A

Vertigo

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6
Q

What is the brand name of dulaglutide?

A

Trulicity

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7
Q

What is the mechanism of action for fexofenadine?

A

Selective H-1 Receptor Antagonist

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8
Q

The mechanism of action of clindamycin topical is to inhibit bacterial protein synthesis by binding to which of the following ribosomal subunits?

A

50S

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9
Q

Which of the following is a major adverse drug reaction for ibandronate?

A

Indigestion

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10
Q

Which of the following is a major adverse drug reaction of cetirizine?

A

Drowsiness

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11
Q

By inhibiting _____, amiodarone may increase the risk of hypoglycemia when combined with glimepiride.

A

CYP2C9

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12
Q

What is the mechanism of action for linagliptin?

A

Prolongs incretin levels

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13
Q

Metformin works by

A

Reducing hepatic glucose production

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14
Q

Which of the following is a major adverse drug reaction for glipizide?

A

Disulfiram reaction

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15
Q

Which of the following is a major adverse drug reaction of liraglutide?

A

Renal failure

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16
Q

Which is the pharmacologic class of insulin glargine?

A

Long-acting insulin

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17
Q

What is the brand name of insulin lispro?

A

Humalog

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18
Q

What is the brand name of insulin aspart

A

Novolog

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19
Q

What is the generic name of Afrezza?

A

Inhaled insulin

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20
Q

What is the generic name of Apidra?

A

Insulin glulisine

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21
Q

Which of the following is the pharmacological class for repaglinide?

A

Meglitinide

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22
Q

Which one of the following is LEAST likely to be involved in CYP450 mediated drug-drug interactions?

A

Dexlansoprazole

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23
Q

The brand name for rosiglitazone is

A

Avandia

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24
Q

Which is a pharmacologic class of dicyclomine?

A

Antimuscarinic

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25
Q

Which of the following is an FDA-approved indication for dutasteride?

A

Benign Prostatic Hyperplasia

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26
Q

What is the brand name of saxagliptin?

A

Onlgyza

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27
Q

What is the mechanism of action for famotidine?

A

H2 antagonism

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28
Q

Pioglitazone works by

A

Increasing insulin sensitivity

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29
Q

Which of the following is a major adverse drug reaction for sitagliptin?

A

Rhabdomyolysis

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30
Q

Is renal dosing adjustment required for canagliflozin?

A

Yes

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31
Q

Which of the following is the pharmacological class for phenazopyridine?

A

analgesic

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32
Q

Which of the following is an FDA-approved indication for darifenacin?

A

Overactive bladder

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33
Q

The brand name for pentosan is

A

Elmiron

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34
Q

Which is a pharmacologic class of polyethylene glycol?

A

Hyperosmotic laxative

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35
Q

Which of the following is an FDA-approved indication for omeprazole?

A

Erosive esophagitis

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36
Q

What is the brand name of rabeprazole?

A

AcipHex

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37
Q

What is the mechanism of action for oxybutynin?

A

Muscarinic Receptor Antagonist

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38
Q

Lubiprostone works by

A

Activating chloride channels

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39
Q

Does ranitidine require dose adjustment for renal dysfunction?

A

Yes

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40
Q

A patient taking metoclopramide with Phenergan would be at greater risk of ___________ compared to a patient taking either drug alone.

A

Tardive dyskinesia

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41
Q

Which of the following is the pharmacological class for tolterodine

A

Antimuscarinic

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42
Q

Which one of the following medications is LEAST likely to decrease tamoxifen activation?

A

Effexor

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43
Q

The brand name for ethinyl estradiol/etonogestrel is

A

NuvaRing

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44
Q

Which is a pharmacologic class of anastrozole?

A

Aromatase Inhibitor

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45
Q

Which of the following is an FDA-approved indication for darbepoetin?

A

Anemia of CKD

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46
Q

Does epoetin require hepatic dose adjustment?

A

No

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47
Q

Cyanocobalamin works by acting as a cofactor for ________ synthesis.

A

Amino acid

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48
Q

Tamsulosin works through ___________ of _____ receptors.

A

Inhibition; alpha-1

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49
Q

Which of the following is an adverse drug reaction for estradiol?

A

Venous thromboembolism

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50
Q

Which of the following is a major adverse drug reaction of epinephrine?

A

Pulmonary edema

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51
Q

Which of the following is the FDA-approved indication for folic acid?

A

Megaloblastic anemia

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52
Q

Which of the following is a major adverse effect of intranasal fluticasone?

A

Glaucoma

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53
Q

The brand name for fluocinonide is __________.

A

Vanos

54
Q

Does methylprednisolone require renal dose adjustment?

A

No

55
Q

One of the FDA-approved indications for topical hydrocortisone is __________.

A

Atopic Dermatitis

56
Q

What is the mechanism of action for medroxyprogesterone?

A

It transforms proliferative into secretory endometrium

57
Q

What is the pharmacologic class of Aranelle?

A

Triphasic oral contraceptive

58
Q

The presumed mechanism of action of mometasone is induction of what?

A

Phospholipase A2 inhibitory proteins

59
Q

Which of the following is a major adverse reaction of levothyroxine?

A

Hyperthyroidism

60
Q

Drospirenone/ethinylestradiol is also known by which brand name?

A

Yasmin

61
Q

The dose of Cialis should be reduced when administered concurrently with:

A

Biaxin

62
Q

Triamcinolone Nasal has an FDA indication for which of the following disease states?

A

Allergic Rhinitis

63
Q

Which of the following is the pharmacological class of prednisone?

A

Adrenal corticosteroid

64
Q

Which of the following describes the mechanism of action of raloxifene?

A

Selectively binds to estrogen receptors

65
Q

An adverse effect of Armour Thyroid is the aggravation of preexisting what type of disease?

A

Cardiovascular

66
Q

Which of the following is a brand name for the pertussis vaccine?

A

Boostrix

67
Q

Which of the following is/are involved in the mechanism of action of etanercept?

A

TNF alpha

68
Q

What is the pharmacological class of sildenafil?

A

Pulmonary hypertension agent

69
Q

Is hepatic dose adjustment required for testosterone?

A

No

70
Q

Which of the following is an adverse drug reaction to the pneumococcal vaccine?

A

Myalgia

71
Q

What is the brand name for Baclofen?

A

Lioresal

72
Q

The combined use of apomorphine and Zofran is contraindicated due to:

A

Additive hypotension

73
Q

Which of the following is an FDA approved indication for carbamazepine?

A

Trigeminal neuralgia

74
Q

Inhibition of phosphodiesterase type 5 to increase the amount of cyclic GMP is the mechanism of action of which drug?

A

Vardenafil

75
Q

Which of the following is a major adverse effect of promethazine?

A

Xerostomia

76
Q

Is renal dose adjustment recommended for tizanidine?

A

Yes

77
Q

Nabumetone belongs to which pharmacological class?

A

NSAID

78
Q

Which of the following is an FDA approved indication for methocarbamol?

A

Musculoskeletal spasm

79
Q

What is the mechanism of action of carbidopa in carbidopa/levodopa?

A

It inhibits decarboxylation of levodopa to allow more to reach the CNS

80
Q

Which of the following is a major adverse drug reaction of cyclobenzaprine?

A

Drowsiness

81
Q

Which of the following is the proposed mechanism of action for clobazam?

A

Potentiation of neurotransmission from binding at the GABA receptor

82
Q

Which of the following is an FDA-approved indication for divalproex?

A

Migraine prophylaxis

83
Q

Which of the following is the brand name for donepezil?

A

Aricept

84
Q

Which of the following is a major adverse drug reaction to lamotrigine?

A

Diplopia

85
Q

Is renal dose adjustment recommended for oxcarbazepine?

A

Yes

86
Q

A proposed mechanism of action of eletriptan is that it produces vasoconstriction through the activation of which intracranial receptors?

A

Serotonin

87
Q

Which of the following types of seizures is an FDA-approved indication for lacosamide?

A

Partial onset

88
Q

What is the generic name for Namenda?

A

Memantine

89
Q

Patient TF has been started on phenytoin for treatment of epilepsy. This is the patient’s first treatment for epilepsy and they have only been on phenytoin for 2 weeks and are still having seizures daily. Patient is also currently on apixaban for stroke prophylaxis. A consult was placed to have pharmacy look at the patient’s medications and make their recommendation. Which of the following is the BEST answer regarding modifying this patient’s medication therapy?

A

Change the patient’s epilepsy medication, potentially to Keppra

90
Q

Which of the following is a major adverse drug reaction to sumatriptan?

A

Cardiac dysrhythmia

91
Q

Cyclosporine inhibits the production of which interleukin?

A

2

92
Q

Which of the following is an FDA-approved indication for loteprednol?

A

Postoperative inflammation

93
Q

Is renal dose adjustment recommended for topiramate?

A

Yes

94
Q

Which of the following is the generic name for lumigan?

A

Bimatoprost

95
Q

Which of the following is a major adverse reaction to celecoxib?

A

Hypertension

96
Q

What does moxifloxacin ophthalmic inhibit as part of its MOA?

A

Topoisomerase II

97
Q

Which of the following is the FDA-approved indication for olopatadine?

A

Allergic Conjunctivitis

98
Q

Which of the following is the pharmacological drug class for travoprost?

A

Prostaglandin

99
Q

What is the brand name of latanoprost?

A

Xalatan

100
Q

The analgesic effects of which one of the following will be reduced if taken together with a strong CYP2D6 inhibitor?

A

Codeine/APAP

101
Q

Which of the following is a major adverse drug reaction for diclofenac?

A

Acute renal failure

102
Q

What is the brand name for etodolac?

A

Lodine

103
Q

Which of the following is an FDA-approved indication for ibuprofen?

A

Fever

104
Q

Which of the following vaccines should be avoided in a patient being treated with a TNF-alpha inhibitor?

A

Varivax

105
Q

Which of the following does Meloxicam inhibit as part of its mechanism of action?

A

COX-1 and COX-2

106
Q

Which of the following is a major adverse drug reaction of hydrocodone?

A

Constipation

107
Q

What is the pharmacological class of the lidocaine topical patch?

A

Local anesthetic

108
Q

Is hepatic dose adjustment required for methadone?

A

No

109
Q

Which of the following is an FDA-approved indication for Kadian?

A

Moderate to severe chronic pain

110
Q

What is the brand name for naproxen?

A

Naprosyn

111
Q

What is the pharmacological class of Tramadol?

A

Opioid

112
Q

What is the generic name for Abilify?

A

Aripiprazole

113
Q

The mechanism of action for benztropine involves inhibiting reuptake and storage of what?

A

Dopamine

114
Q

Which of the following is an FDA-approved indication of prochlorperazine?

A

Anxiety

115
Q

Which of the following is a major adverse drug reaction to Lithium?

A

Hypothyroidism

116
Q

Are there hepatic dose limitations for citalopram?

A

Yes

117
Q

What is the brand name for buspirone?

A

Buspar

118
Q

Which of the following is an FDA-approved indication for lurasidone?

A

Schizophrenia

119
Q

Desvenlafaxine is a potent reuptake inhibitor of what?

A

Norepinephrine

120
Q

Metabolic clearance of which of the following will be affected by smoking tobacco?

A

Zyprexa

121
Q

Which one of the following is LEAST likely to be involved in CYP450 mediated drug-drug interactions?

A

Ziprasidone

122
Q

What is the generic name for Harvix?

A

Hepatitis A Vaccine

123
Q

Which of the following is an FDA-approved indication for tacrolimus?

A

Liver transplant rejection

124
Q

Which of the following is a major adverse drug reaction to the influenza vaccine?

A

Which of the following is a major adverse drug reaction to the influenza vaccine?

125
Q

Risperidone is a potent antagonist of what?

A

Serotonin

126
Q

Which of the following is an approved FDA indication of Recombivax HB?

A

Prevention of Hepatitis B infection

127
Q

Is renal dosage adjustment required for quetiapine?

A

No

128
Q

Which of the following is the pharmacological class for the HPV vaccine?

A

Vaccine, Inactivated, Viral

129
Q

Which of the following is a brand name for Haemophilus Influenzae Type B Vaccine?

A

Hiberix

130
Q

Which of the following is an approved FDA-indication of potassium iodide?

A

Prevention of thyroid dysfunction due to radiation exposure

Spring Top 300 drugs (1 decks)

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