spleen Flashcards

1
Q

Lymph nodes

A

effectively filter foreign antigens from lymph and mount an immune response to protect the organism

The spleen filter foreign antigens from blood and mount an immune response to protect the organism

In addition the spleen removes particulate matter, senescent erythrocytes and platelets from the circulation

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2
Q

Spleen connective tissue

A

capsule and trabeculae which project into the organ

Spleen consists of cords of cells separated by sinusoids

The blood filled sinusoids stain red- red pulp

The cords are densely packed lymphocytes in between the sinusoids stain blue- White pulp

As blood percolates thru sinusoids and other spaces within the spleen the RBCs need to squeeze thru narrow spaces. less flexible plasma membranes and may lyse during this passage, the RBC fragments are then phagocytosed by Macrophages positioned along passageways

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