Spiranolactone

Question 1

T 1/2 of spiranolactone

Answer 1

1 to 2 hours

Question 2

T 1/2 of canrenone

Answer 2

18 hours

Question 3

Potassium retaining action of spiranolactone starts after how many days

Answer 3

3 to 4 days

Question 4

Asprin and spiranolactone

Answer 4

Asprin blocks tubular secretion of spiranolactone

Question 5

Digoxin and spiranolactone

Answer 5

Level of digoxin increases

Question 6

Cx for aldactone

Answer 6

Ulcer and hyperkalemia

Question 7

Eplerenonone t1/2

Answer 7

4 to 6 hours

Question 8

Metabolism of eplerenone

Answer 8

Cyp3a4, inhibitors increase the level, inducer decrease the level

Question 9

After what time and% of patients aldosterone level becomes normal in RAAS therapy

Answer 9

Several weeks, in 30 to 40 %

Question 10

Rales trial, NYHA? Which group

Answer 10

Nyha3, HF

Question 11

Which trial studied MRA in MI? Which in NYHA class 2

Answer 11

Ephesus , Emphasis

Question 12

Endorcrine abnormalities in sprinolactone

Answer 12

Painful gynecomastia

Menstrual irregularites in premenopausal women

Impotence and libido loss in men

Question 13

What to do if gynecomastia occurs

Answer 13

Stop and start eplerenone

Question 14

Which trial compares finerenone vs eplerenone

Answer 14

ARTS HF phase 2 trial