spinal and epidural part 4 Flashcards
causes of unilateral block
catheter may be inserted too far
catheter tip might be too close to a nerve
the 4 solutions discussed in lecture for unilateral block
adjust the catheter (pull back 1-2 cm) ensure 3-5 remains in epidural space
reposition patient
administer more anesthetic
catheter replacement
most frequent symptom of LAST
seizure
with bupivacaine cardiac arrest may come before seizure
when is LAST more common
peripheral nerve blocks
s/s lidocaine toxicity 1-5mcg/mL
analgesia
s/s lidocaine toxicity 5-10mcg/ml
tinnitus
skeletal muscle twitching
numbness of lips and tongue
restlessness
vertigo
blurred vision
hypotension
myocardial depression
s/s lidocaine toxicity 10-15mcg/mL
seizures
loss of consciousness
s/s lidocaine toxicity 15-25mcg/mL
coma
respiratory arrest
s/s lidocaine toxicity >25mcg/mL
CV collapse
CNS toxicity from LAST risk increase with
hypercarbia
hyperkalemia
metabolic acidosis
CNS toxicity from LAST risk decrease with
hypocarbia
hypokalemia
CNS depressants
CV toxicity bupivacaine impact of LA on heart functions
decrease heats automaticity, conduction velocity, action potential duration nd effective refractory period
depress myocardium by affects intracellular calcium regulation
key factors determining the extent of cardiotoxicity
LA affinity tot he voltage sodium channels in active and inactive states
rate of dissociation from the receptor during diastole
bupivacaine has a ________ affinity to voltage sodium channel and a _________ dissociation rate from receptor during diastole
high affinity
slower dissociation
difficulty of cardiac resuscitation from most to least
bupivacaine
levobupivacaine
ropivacaine
lidocaine