Spectrum of CAD

Question 1

3 chest pain criteria for typical angina

Answer 1

Substernal chest discomfort with characteristic quality and duration
Provoked by exertion or emotional stress
Relieved promptly by rest or nitroglycerin

Question 2

Unstable angina

Answer 2

Transient acute ischemia not resulting in myocardial injury
Vulnerable plaque
Typical symptoms, negative biomarkers, +/- ischemic changes

Question 3

Non ST elevation MI

Answer 3

Subendocardial ischemia resulting in myocardial injury

Question 4

ST elevation MI

Answer 4

Acute transmural ischemia resulting in characteristic ECG changes (and associated myocardial injury)

Question 5

Troponin I vs T

Answer 5

I: exclusive to cardiac myocytes
T: small amount skeletal muscle