Spectrum of Activity Flashcards

1
Q

Natural penicillins cover what bacteria?

A

Streptococci

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2
Q

Penicillinase-Resistant penicillins cover what bacteria?

A

MSSA and Streptococci

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3
Q

Aminopenicillins cover what bacteria?

A

Streptococci, Enterococci (only against Enterococci spp. that are sensitive to ampicillin), and Gram Negative Rods (only species that don’t produce B-lactamase)

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4
Q

Antipseudomonal penicillins cover what bacteria?

A

Streptococci, Enterococci (only those sensitive to ampicillin), Gram negative rods, and P. aeruginosa

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5
Q

Penicillin-based B=lactamase inhibitor combos cover what bacteria?

A

MSSA, streptococci, Enterococci (only those sensitive to ampicillin), Gram negative rods, P. aeruginosa (only ones that include an antipseudomonal penicillin) and Bacteroides

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6
Q

1st gen Cephalosporins cover what bacteria?

A

MSSA, Streptococci, Proteus mirabilis, E. coli, Klebsiella spp. (PEcK)

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7
Q

2nd gen Cephalosporins cover what bacteria?

A

MSSA, Streptococci, Gram neg rods: Haemophilus influenzae, Moraxella catarrhalis, Proteus mirabilis, E. coli, Klebsiella spp. (HiMPEcK). Cefoxitin and Cefotetan ONLY cover Bacteroides.

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8
Q

NO penicillins cover which bacteria?

A

MRSA

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9
Q

3rd gen Cephalosporins cover what bacteria?

A

MSSA (not ceftazidime), Streptococci (not ceftazidime), Gram neg rods: Haemophilus influenzae, Moraxella catarrhalis, Proteus mirabilis, E. coli, Klebsiella spp. (HiMPEcK) and Serratia spp., Proteus spp. (mirabilis+vulgaris), Acinetobacter spp., Citrobacter spp., and Enterobacter spp. (SPACE). P. aeruginosa is only covered by Ceftazidime

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10
Q

4th gen Cephalosporins cover what bacteria?

A

MSSA, Streptococci, HiMPEcK, SPACE, and Extended Spectrum B-Lactamase-producers, and P. aeruginosa

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11
Q

5th gen Cephalosporins cover what bacteria?

A

MSSA, MRSA, Streptococci, HiMPEcK

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12
Q

Cephalosporin-based B-lactamase inhibitor combos cover what bacteria?

A

Streptococci, PEcK, enterobacter spp., P. aeruginosa, and Bacteroides spp. when used in combination with metronidazole.

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13
Q

Carbapenems (except Ertapenem) cover what bacteria?

A

MSSA, Streptococci, E. faecalis (sensitive to ampicillin), Gram negative rods, P. aeruginosa, and Bacteroides

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14
Q

Ertapenem covers what bacteria?

A

MSSA, Streptococci, Gram negative rods, and Bacteroides.

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15
Q

Aztreonam covers what bacteria?

A

Gram negative rods, and P. aeruginosa.

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16
Q

The acronym: PEcK stands for what?

A

Proteus mirabilis, E. coli, Klebsiella spp.

17
Q

The acronym: HiMPEcK stands for what?

A

Haemophilus influenzae, Moraxella catarrhalis, Proteus mirabilis, E. coli, Klebsiella spp.

18
Q

The acronym: SPACE stands for what?

A

Serratia spp., Proteus spp. (miribilis+vulgaris), Acinetobacter spp., Citrobacter spp., Enterobacter spp.

19
Q

Glycopeptides cover what bacteria?

A

MSSA, MRSA, Streptococci, and Enterococci

20
Q

Lipoglycopeptides cover what bacteria?

A

MSSA, MRSA, Streptococci, and Enterococci