Spectrum of Activity Flashcards
Natural penicillins cover what bacteria?
Streptococci
Penicillinase-Resistant penicillins cover what bacteria?
MSSA and Streptococci
Aminopenicillins cover what bacteria?
Streptococci, Enterococci (only against Enterococci spp. that are sensitive to ampicillin), and Gram Negative Rods (only species that don’t produce B-lactamase)
Antipseudomonal penicillins cover what bacteria?
Streptococci, Enterococci (only those sensitive to ampicillin), Gram negative rods, and P. aeruginosa
Penicillin-based B=lactamase inhibitor combos cover what bacteria?
MSSA, streptococci, Enterococci (only those sensitive to ampicillin), Gram negative rods, P. aeruginosa (only ones that include an antipseudomonal penicillin) and Bacteroides
1st gen Cephalosporins cover what bacteria?
MSSA, Streptococci, Proteus mirabilis, E. coli, Klebsiella spp. (PEcK)
2nd gen Cephalosporins cover what bacteria?
MSSA, Streptococci, Gram neg rods: Haemophilus influenzae, Moraxella catarrhalis, Proteus mirabilis, E. coli, Klebsiella spp. (HiMPEcK). Cefoxitin and Cefotetan ONLY cover Bacteroides.
NO penicillins cover which bacteria?
MRSA
3rd gen Cephalosporins cover what bacteria?
MSSA (not ceftazidime), Streptococci (not ceftazidime), Gram neg rods: Haemophilus influenzae, Moraxella catarrhalis, Proteus mirabilis, E. coli, Klebsiella spp. (HiMPEcK) and Serratia spp., Proteus spp. (mirabilis+vulgaris), Acinetobacter spp., Citrobacter spp., and Enterobacter spp. (SPACE). P. aeruginosa is only covered by Ceftazidime
4th gen Cephalosporins cover what bacteria?
MSSA, Streptococci, HiMPEcK, SPACE, and Extended Spectrum B-Lactamase-producers, and P. aeruginosa
5th gen Cephalosporins cover what bacteria?
MSSA, MRSA, Streptococci, HiMPEcK
Cephalosporin-based B-lactamase inhibitor combos cover what bacteria?
Streptococci, PEcK, enterobacter spp., P. aeruginosa, and Bacteroides spp. when used in combination with metronidazole.
Carbapenems (except Ertapenem) cover what bacteria?
MSSA, Streptococci, E. faecalis (sensitive to ampicillin), Gram negative rods, P. aeruginosa, and Bacteroides
Ertapenem covers what bacteria?
MSSA, Streptococci, Gram negative rods, and Bacteroides.
Aztreonam covers what bacteria?
Gram negative rods, and P. aeruginosa.