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Spectrum of activity Flashcards

1
Q

Penicillin G/V

A

Streptococcus ABCD, pneumoniae
enterococcus faecalis
finagoldia magna

yellow: MSSA

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2
Q

amoxicillin/ampicillin

A

Streptococcus ABCD, pneumoniae
enterococcus faecalis
finagoldia magna
E.coli

yellow: MSSA, haemophilus influenzae

penicillin + e.coli, haemophilus

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3
Q

cloxacillin

A

MSSA
streptococcus ABCD

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4
Q

amoxicillin-clavulanate

A

gram +ves (except MRSA):
MSSA
streptococcus ABCD, pneumoniae
enterococcus faecalis
finagoldia magna

gram -ves:
bacteroides fragilis
haemophilus influenzae
E.coli, Klebsiella, Proteus mirabilis

ESBL-producing Ecoli, Kleb (only cystitis)

amoxillin + gram -ve

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5
Q

piperacillin-tazobactam

A

gram +ves (except MRSA):
MSSA
streptococcus ABCD, pneumoniae
enterococcus faecalis
finagoldia magna

gram -ves:
bacteroides fragilis
haemophilus influenzae
E.coli, Klebsiella, Proteus mirabilis
Pseudomonas aeruginosa

yellow (cystitis only): ESBL-producing Ecoli, Kleb, enterobacter

amoxicillin-clavulanate + pseudomonas

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6
Q

cefazolin, cephalexin

A

MSSA
streptococcus ABCD
finagoldia magna

haemophilus influenzae
E.coli, Klebsiella, Proteus mirabilis

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7
Q

cefuroxime

A

MSSA
streptococcus ABCD, pneumoniae
finagoldia magna

haemophilus influenzae
E.coli, Klebsiella, Proteus mirabilis

1st gen + strep pneumo

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8
Q

ceftriaxone

A

MSSA
streptococcus ABCD, pneumoniae
finagoldia magna
enterococcus fecalis (in combination)

haemophilus influenzae
E.coli, Klebsiella, Proteus mirabilis
enterobacter (cystitis only)

cefuroxime + yellow stuff

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9
Q

ceftazidime

A

finegoldia magna

haemophilus influenzae
E.coli, Klebsiella, Proteus mirabilis
pseudomonas
enterobacter (cystitis only)

ceftriaxone - g+ve + pseudomonas

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10
Q

cefepime

A

MSSA
streptococcus ABCD, pneumoniae
finagoldia magna

haemophilus influenzae
E.coli, Klebsiella, Proteus mirabilis
pseudomonas
ESBL producing ecoli, kleb (cystitis only)
enterobacter (non serious infection only)

ceftrixone + pseudomonas

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11
Q

ceftaroline

A

MRSA, MSSA
streptococcus ABCD, pneumoniae
finagoldia magna

haemophilus influenzae
E.coli, Klebsiella, Proteus mirabilis
enterobacter (cystitis only)

ceftriaxone + MRSA

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12
Q

meropenem, imipenem, doripenem

A

MSSA
Streptococcus ABCD, pneumoniae
enterococcus faecalis
finagoldia magna

Bacteroides fragilis
haemophilus influenzae
E.coli, Klebsiella, Proteus mirabilis
ESBL producing ecoli, kleb
enterobacter
pseudomonas

everything except MRSA

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13
Q

ertapenem

A

MSSA
Streptococcus ABCD, pneumoniae
finagoldia magna

Bacteroides fragilis
haemophilus influenzae
E.coli, Klebsiella, Proteus mirabilis
ESBL producing ecoli, kleb
enterobacter

meropenem - enterococcus fecalis, pseudomonas

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14
Q

erythromycin

A

atypicals (legionella, mycoplasma pneumoniae, chlamydia pneumoniae)

yellow: MSSA, streptococcus ABCD, pneumoniae, haemophilus influenzae

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15
Q

clarithromycin, azithromycin

A

atypicals (legionella, mycoplasma pneumoniae, chlamydia pneumoniae)
haemophilus influenzae

yellow: MSSA, streptococcus ABCD, pneumoniae

erythromycin + haemophilus

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16
Q

doxycycline

A

finagoldia magna

haemophilus influenzae

atypicals (legionella, mycoplasma pneumoniae, chlamydia pneumoniae)

yellow:
MRSA, MSSA, strep ABCD, pneumoniae
Ecoli, kleb, proteus mirabilis, ESBL producing ecoli + kleb, enterobacter

17
Q

gentamicin

A

Ecoli, kleb, proteus mirabilis
ESBL producing ecoli + kleb
enterobacter

yellow:
MSSA, enterococcus fecalis (only in combination)
use in pseudomonas controversial

g -ve

18
Q

amikacin

A

Ecoli, kleb, proteus mirabilis
ESBL producing ecoli + kleb
enterobacter

pseudomonas (UTI only)

gentamicin - yellow stuff

19
Q

ciprofloxacin

A

MRSA/MSSA (NOT USED)
enterococcus fecalis (only in ucUTI)

haemophilus influenzae
Ecoli, Kleb, Proteus
pseudomonas

yellow:
ESBL producing ecoli/kleb, enterobacter

20
Q

levofloxacin

A

MRSA/MSSA (USE WITH CAUTION)
streptococcus ABCD, pneumoniae
enterococcus fecalis (only in ucUTI)

haemophilus influenzae
Ecoli, Kleb, Proteus
pseudomonas

atypicals

yellow:
ESBL producing ecoli/kleb, enterobacter

cipro + strep + atypicals

21
Q

moxifloxacin

A

MRSA/MSSA (USE WITH CAUTION)
streptococcus pneumoniae
finagoldia magna

haemophilus influenzae

atypicals

yellow:
bacteroides fragilis
Ecoli, Kleb, Proteus, ESBL producing ecoli/kleb, enterobacter (no breakpoints)

levo -strep ABCD, pseudomonas + anaerobes

22
Q

trimethoprim/sulfamethoxazole

A

MRSA, MSSA

E.coli, kleb, proteus

yellow:
streptococcus pneumoniae
haemophilus influenzae, ESBL producing Ecoli/kleb, enterobacter

23
Q

vancomycin

A

MRSA, MSSA
streptococcus ABCD, pneumoniae
enterococcus fecalis
clostridiodes difficile (PO)

g +ve

24
Q

metronidazole

A

finegoldia magna
clostridiodes difficile

bacteroides fragilis

anaerobes

25
clindamycin
finegoldia magna yellow: MRSA, MSSA, strep bacteroides fragilis
26
MRSA
ceftaroline trimethoprim/sulfamethoxazole vancomycin yellow: clindamycin, doxycycline active but not used: fluoroquinolones
27
MSSA
penicillins (except G/V, amoxicillin) cephalosporins (except ceftazidime) carbapenems trimethoprim/sulfamethoxazole vancomycin yellow: macrolides, tetracyclines, clindamycin, gentamicin (in combination)
28
streptococcus ABCD
penicillins cephalocporins (exccept ceftazidime) carbapenems levofloxacin vancomycin yellow: macrolides, tetracyclines, clindamycin
29
streptococcus pneumoniae
penicillins (except cloxacillin) cephalosporins (except 1st gen, ceftazidime) carbapenems levofloxacin, moxifloxacin vancomycin yellow: macrolides, doxycycline, clindamycin, trimethoprim/sulfamethoxazole
30
enterococcus fecalis
penicillins (except cloxacillin) ceftriaxone + gentamicin vancomycin cipro/levofloxacin (ucUTI only)
31
finegoldia magna (g +ve anaerobe)
penicillins (except cloxacillin) cephalosporins carbapenems tetracyclines moxifloxacin clindamycin metronidazole
32
clostridiodes difficile (g +ve anaerobe)
vancomycin (PO) metronidazole
33
baceroides fragilis (g -ve anaerobe)
amoxicillin-clavulanate, piperacillin-tazobactam carbapenems metronidazole yellow: moxifloxacin, clindamycin
34
haemophilus influenzae
amoxicillin-clavulanate, piperacillin-tazobactam cephalosporins carbapenems macrolides (erythromycin - yellow) tetracyclines fluoroquinolones yellow: amoxicillin, ampicillin, erythromycin, trimethoprim/sulfamethoxazole
35
e.coli, klebsiella, proteus mirabilis
amoxicillin, ampicillin (ecoli only) amoxicillin-clavulanate, piperacillin-tazobactam cephalosporins carbapenems aminoglycosides fluoroquinolones (except moxifloxacin) trimethoprim/sulfamethoxazole yellow: doxycycline, moxifloxacin
36
ESBL producing ecoli, kleb
carbapenems aminoglycosides yellow: amoxicillin-clavulanate, piperacillin-tazobactam, cefepime (cystitis only) doxycycline fluoroquinolones trimethoprim/sulfamethoxazole
37
enterobacter (Amp-C producing GNR)
cabapenems aminoglycosides yellow: piperacillin-tazobactan, 3rd+5th gen cephalosporins (cystitis only) cefepime (non-serious infections only) fluoroquinolones trimethoprim/sulfamethoxazole
38
pseudomonas aeruginosa
piperacillin-tazobactam cetftazidime, cefepime meropenem, imipenem, doripenem (carbapenems - ertapenem) cipro/levofloxacin (fluoroquinolones - moxifloxacin) amikacin (UTI only)
39
atypicals (legionella, mycoplasma pneumoniae, chlamydia pneumoniae)
macrolides tetracyclines levo/moxifloxacin (fluoroquinolones - cipro)

PR3151 (3 decks)

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