Specimen Collection and Processing For Hemostasis Flashcards
Hemostasis and its mechanisms and factors
Factor I
Fibrinogen
Factor II
Prothrombin, Prethrombin
Factor III
Tissue Factor, Tissue Thromboplastin
Factor IV
Calcium
Factor V
Proaccelerin, Labile factor, Accelerator globulin
Factor VII
Proconvertin, Stable factor, Serum Prothrombin Conversion Accelerator (SPCA), Autothrombin
Faactor VIII
Antihemophillic factor (AHF), Antihemophillic Globulin (AHG), Antihemophillic factor A, Platelet Cofactor I
Factor IX
Plasma Thromboplastin Component (PTC), Christmas factor, Antihemophillic factor B, Platelet Cofactor II
Factor X
Stuart-Prower factor, stuart factor, Prower factor, Autoprothrombin III
Factor XI
Plasma Thromboplastin Antecedent, Antihemophillic factor C
Factor XII
Hageman factor, Glass factor, Contacf factor
Factor XIII
Fibrin-Stabilizing factor, Laki-Lorand factor, Fibrinase, Plasma Transglutaminase, Fibrinoligase
Prekallikrein
Fletcher factor, Contact Activation Factor, Fitzgerald factor, Flaujac factor, William factor
HMWK
High-Molecular Weight Kinnogen
Three groups of Factors
Fibrinogen group, Prothrombin group/Vutamin K dependent, and Contact group
It is consumed during the Process of coagulation.
Decreases during blood storage in vitro.
Increases in pregnancy, conditions of inflammation and subsequent use of oral contraceptive drugs
Fibrinogen group
Factors in the Fibrinogen group
I, V, VIII, and XIII
Dewndent on vit. K for ther synthesis in the liver.
Inhibited by warfarin but stable and well preserved in stored plasma
Prothrombin group/ Vitamin K dependent
Factors in the Prothrombin group
Ii, VII, IX, and XIII
Involved in the intrinsic Coagulation Pathway.
Moderately stable and are not cosumed during cogulation.
Contact group
Factors in Contact group
XI, XII, Prekalikrein, and HMWK
