Specific diseases Flashcards
UTI with reduced GFR
Trimethoprim 200mg BD (nitrofurantoin contraindicated when GFR <45)
IV treatment for severe hypoglycaemia
20% glucose 50-100mL (10-20g)
10% glucose 100-200mL
VTE prophylaxis following THR
Rivaroxaban 10mg
Dalteparin 10000 units
Asthma Attack
oxygen driven salbutamol nebuliser 5mg PRN
ipratropium 500micrograms NEB PRN - if acute severe/life threatening
prednisolone 50mg PO or hydrocortisone 200mg IV
poor response -
add ipratropium f moderate
IV magnesium sulfate 2g over 20 mins if severe/life threatening
pregnancy pain relief
NSAID fine
Avoid aspirin - Reye’s syndrome
malignant cord compression
dex 16 IV/PO then 8mg BD
antiemetic - nauseated
regular cyclizine - 50mg 8 hourly - IM/IV/PO
antiemetic - not nauseated
PRN cyclizine 50mg up to 8 hourly
antiemetic - heart failure
metoclopromide 10mg 8 hourly (reg or PRN depending on nausea)
maintenance fluids
25-35ml/kg/day water
50-100g/day glucose
1 mmol/kg/day Na, K and Cl
torsades de pointes
2g magnesium over 10 mins
STEMI
ABC and O2 aspirin 300 morphine 5-10 + metoclopramide 10 GTN PCI BB
NSTEMI
ABC and O2 aspirin 300 morphine 5-10 + metoclopramide 10 GTN BB LMWH Clopidogrel
LVF
sit up ABC 02 morphine 5-10 and metoclpramide 10 furosemide 40 IV nitrates and CPAP
anaphylaxis
Abc and O2 adrenaline 500mcg 1:1000 IM chlorphenamine Iv 10 hydrocortisone 200 IV treat wheeze - as per asthma
AE asthma or COPD
oxygen
salbutamol 5mg neb
hydrocortisone 100 IV or pred PO 40-50
ipratropium 500 micrograms neb
theophylline if life threatening
COPD: same management but add antibiotics if infective - amoxicillin
Bacterial meningitis
oxygen fluid dex IV LP +/- CT head 2g cefotaxime
upper GI bleed
ABC O2 Iv access and cannula fluid and crossmatch blood endoscopy stop - NSAIDs, aspirin, warfarin, LMWH
seizures and status
ABC recovery position and oxygen lorazepam 2-4mg IV (or diazepam buccal 10) 2 mins - repeat anaesthetist phenytoin intubate and propofol
stroke
ABC glucose CT head assuming ischaemic: <80 and <4.5 hours - alteplase aspirin 300 stroke unit
hyperglycaemia
Iv fluid 1L stat, then 1L over 1 hour then 2 hours then 4 hours then 8 hours
sliding scale insulin
monitor BM, k and pH
AKI
catheter and cannula for fluid monitoring
IV fluid 500 stat then 1L 4 hourly
paracetamol OD
NAC
>4 hours
check levels
benzo OD
flumazenil
opioid
naloxone
when to treat hypertension
150/95
or 135/85 with:
diabetes, vascular disease, hypertensive organ damage
aim<140/85 in clinic (130/80 home) +10 mmHg for every year over 80
chronic heart failure
ACE and BB - lisinopril 2.5 and bisoprolol 1.25
increase doses as tolerated
mild mod - candesartan 4mg
african-carribean - hydralazine 25 and isonitrate 20
mod severe - spironolactone 25mg
AF
rate >90 - beta blocker, diltiazem
digoxin if both tolerated
stable angina
GTN PRN
secondary prevention - aspirin and statin
anti-anginal - BB or CCB
asthma
SABA
ICS
LTRA/LABA
increase steroid
COPD
SABA
LAMA/LABA
LABA/ICS
triple therapy
secondary prevention in diabetes
aspirin (RFs or >50)
statin (RFs or >40)
ACR - ACEi
glue lowering therapy
T2DM
>48 after lifestyle metformin >58 gliclizide DPP4 pioglitazone aiming 53 for when there is 2 or more drugs
tonic clonic seizure
valproate
myoclonic seizure
valproate
absence
valproate or ethosuximide
focal
lamotrigine or carbemazepine
epilepsy pregnant
lamotrigine
alzheimers
only started by specialists
mild moderate - ACHEi rivastigmine, donepazil,
severe - NMDA - memantine
IBD
crohns
induce remission: steroid
maintenance: azathioprine
UC
induce remission: mesalazine (IV hydrocortisone if severe)
maintain: mesalazine
obstruction
drip and suck
never give a laxative
insomnia
zopiclone
nausea in PD
domperidone
avoided in ischaemic heart disease
NSAIDs
oestrogens
Varenicline
acute dystonic reaction
procyclidine