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Step 1 Pharmacology > Specific Antidotes > Flashcards

Specific Antidotes Flashcards

1
Q

Acetaminophen toxicity

A

Replenishes glutathione

N-acetylcysteine

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2
Q

ACh Esterase inhibitors

Organophosphates

A

Atropine
Pralidoxime

where Atropine>Pralidoxime

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3
Q

Amphetamine overdose

A

NH4Cl to acidify the urine becase amphetamines are basic

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4
Q

Heparin

A

Protamine sulfate

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5
Q

Iron overload

A

De - feroxamine

De - ferasirox

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6
Q

Opiods

A

Naloxone

Naltrexone

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7
Q

Warfarin

A 
Vitamin K (delayed effect)
Fresh frozen plasma (more immediate effect)
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8
Q

Beta blocker overdose

A

Glucagon

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9
Q

Antimuscarinic or Anticholinergic agents

A

Physostigmine salicylate

Control hyperthermia

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10
Q

Carbon monoxide poisoning

A

100% O2

Hyperbaric O2

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11
Q

Copper
Arsenic
Gold

A

Penicillamine

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12
Q

Benzodiazepines

A

Flumazenil

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13
Q

Cyanide

A

Nitrite + thiosulfate

Hydroxocobalamin

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14
Q

tPA
Streptokinase
urokinase

A

Aminocaproic acid

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15
Q

Arsenic

A

Penicillamine

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16
Q

TCAs

Tricyclic Acid

A

NaHCO3 to alkalinize the plasma

17
Q

Copper

A

Penicillamine

18
Q

Lead poisoning

A

EDTA
Dimercaprol
Succimer
Penicillamine

19
Q

Salicylates

A

NaHCO3 to alkalinize the urine

Dialysis

20
Q

Gold

A

Penicillamine

21
Q

Mercury

A

DiMERCaprol (BAL)

Succimer

22
Q

Mercury
Arsenic
Gold

A

DiMERCaprol (BAL)

Succimer

23
Q 
Methanol
Ethylene glycol (antifreeze)
A

Fomepizole is the usual answer
ETOH also works
dialysis works too!

24
Q

METHemoglobin

A

Methylene blue and Vitamin C

25
Digitalis (Digoxin)
Anti-Dig Fab fragments

Step 1 Pharmacology (6 decks)

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