Specialty Tertiary Resources

Question 1

AHFS Drug Information (American Hospital Formulary Service)

Answer 1

• Primary utilization: general drug information
• Published through the American Society of Health-System Pharmacists (ASHP)
o Organized by pharmacological classification system
• Monograph information for individual drugs
o Brand name
o Class
o Uses
o Dose and administration
 How to reconstitute
 Renal/hepatic adjustments
 Pre-treatment medications
o Cautions
o Drug interactions
o Acute toxicity (the mechanism behind it and how to treat it)
o Pharmacokinetics
o Chemistry and stability b
o Pricing with manufacturers
o References
• Available by electronic access through LexiComp Online

Question 2

Handbook on Injectable Drugs (Trissel’s)

Answer 2

• Primary utilization: IV compatibility, stability, preparation of IV medications, and some pharmaceutical preparation
• How to interpret Trissel’s
o A drug monograph includes a list of other medications and their possible compatibility
o Includes designations “C” for compatible, “I” for incompatible, and “u” for uncertain or variable (in electronic version only)
o Internally referenced
o Please see next page for illustration on the use of Trissel’s
• Also of note, includes some pharmaceutics, administration, and storage information.
• Electronic access is also available through Micromedex, Clinical Pharmacology, and Lexicomp

Question 3

ImmunoFacts

Answer 3

• Primary utilization: vaccine and immunologic agents information
• Begins by providing basic immunologic principles to the user
• For vaccines it describes:
o Efficacy studies
o FDA-labeled indications
o Off-label indications if they exist
o Contraindications
o Special groups
o Adverse reactions
o Dosage
o Route
o Pharmaceutical information
o Storage
o Production process
• Includes a section for vaccine-to-vaccine interactions and a list of manufacturers of vaccines and immunologics.
• Provides important paperwork to be on file or given to patients for immunization.
• Glossary of terminology as it relates to vaccines, immunologicals, and immunology pri
• nciples.

Question 4

Red Book: 2015 Report of the Committee on Infectious Diseases

Answer 4

• Primary utilization: providing information regarding immunization and infectious disease information as it relates to pediatrics
• Published by the Committee on Infectious Diseases of the American Academy of Pediatrics (AAP).
• Organized by:
o Vaccine and immunization information
o General health information
o Infectious disease information by specific disease
o Dosing of certain medications in pediatrics
o Appendix information
 Vaccine safety reporting
 Clinical syndromes with foodborne disease
 Prophylaxis measures
 Guidelines for immunization programs
 Contraindications and warnings to vaccinations

Question 5

Pediatric Injectable Drugs (Teddy Bear Book)

Answer 5

•	Primary utilization: dosing and administration of injectable drugs for pediatric and neonatal patients
•	Organized alphabetically by drug name
•	Includes the following information for each drug:
o	Dose by age category
o	Administration considerations
o	Necessary pre-medications
o	Medication error potential
o	Infusion-related cautions
o	Suitable diluents
o	IV push
o	Other routes of administration
•	Electronic access is also available through ASHP (link on BI Resource page under Electronic Textbooks)

Question 6

The Sanford Guide to Antimicrobial Therapy

Answer 6

• Primary utilization: infectious disease information, including drugs
• Other guides available for HIV/AIDS Therapy, Hepatitis Therapy and Lederman’s Internal Medicine and Critical Care Guide
• Organized by organ system
o Gives drug of choice for each disease state
• Other information
o Bug/drug susceptibility
o HIV and other viral treatment
o Nematode and parasite treatment
o Renal dosing and adverse effects of antibiotics

Question 7

Johns Hopkins Guides

Answer 7

• 4 guides available: ABX, Diabetes, HIV, Psychiatry
• Primary utilization: need to know information related to disease(s) and drug(s) related to the different areas
• Published by the Johns Hopkins University via the POC-IT Center
o Majority (if not all) of editors are specialists within the guide field at Johns Hopkins University
• Organized alphabetical by all topics (at least main screen)
o Additional sections vary by individual guide
 Example (ABX Guide): Antibiotics, Diagnosis, Management, Pathogens, Vaccines, Brand Names
• Electronic access available through the BI Resources page
o Mobile access available (see instructions on Mobile tab in uCentral)

Question 8

The Harriet Lane Handbook

Answer 8

• Primary utilization: pediatric diagnostic and treatment information
• Published by physicians at The Johns Hopkins Hospital
• Organized into sections:
o Acute care
o Diagnostic and therapeutic information (alphabetical by system)
o References
o Formulary

Question 9

Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5TM)

Answer 9

• Primary utilization: assist clinicians in diagnosis and clinical assessment of mental disorders
• Published by the American Psychiatric Association
• Organized by class/type of mental disorder
o Then by subclass/subtype of disorder – more specific features
• Does not contain specific drug therapy recommendations

Question 10

Plumb’s Veterinary Drug Handbook

Answer 10

• Primary utilization: drug information related to veterinary pharmacy
• Organized by alphabetically by generic name
o Systemic monographs first followed by ophthalmic, dermatologic (topical) and otic preparations
o Includes phone number and websites specific to veterinary practice
• Provides drug information for human and veterinary labeled pharmaceuticals