Special Senses Flashcards

1
Q

Which neurotransmitter do cells of the inner ear release, in order to cause an AP to fire?

A

Glutamate

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2
Q

When a K+ channel opens in the hair cells of the inner ear, what happens?

A

The K+ moves into the cell

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3
Q

Complete the sentence: the labyrinth has a ? exterior, what a smaller but similarly shaped ? labyrinth within it

A

Bony / membranous

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4
Q

What type of fluid fills the space between the bony and membranous labyrinths? What is this composed of?

A

Perilymph - plasma and CSF

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5
Q

The membranous labyrinth is filled with what type of fluid? What differentiates this from the fluid found between the bony and membranous labyrinths?

A

Endolymph / it has a higher K+ concentration

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6
Q

Sound causes vibration of the air, which in turn causes vibration of which structures?

A

The tympanic membrane and the ossicles (malleus, incus, stapes)

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7
Q

What structures in the inner ear work to attenuate the movement of the tympanic membrane and stapes respectively to protect against excessive noise damage?

A

Tensor tympani and stapedius muscles

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8
Q

Complete the sentence: vibration of the cochlea causes movement of the ? situated within an endolymph filled spiral organ, the ?, within the cochlea

A

Basilar membrane / Organ of Corti

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9
Q

Where in the inner ear is vibration of air converted to movement/vibration of fluid?

A

In the cochlea

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10
Q

Complete the sentence: vibration of fluid within the cochlea causes the ? within the Organ of Corti to bend against the ? which results in ?, generating an AP

A

Cilia of hair cells / tectorial membrane / depolarisation

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11
Q

After an action potential is generated in the Organ of Corti, what happens?

A

Physical vibration is converted into neural energy, and the AP is carried along the auditory nerve (part of CNVIII)

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12
Q

From the auditory nerve (part of CNVIII), information is passed into where?

A

The auditory cortex in the temporal lobe

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13
Q

Which structure of the inner ear can discriminate between different pitches?

A

Basilar membrane

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14
Q

The hair cells within the Organ of Corti are actually what?

A

Auditory receptors with stereocilia

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15
Q

What happens when the Organ of Corti is displaced?

A

The hair cells are displaced, resulting in the opening of K+ channels and the release of glutamate

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16
Q

Complete the sentence: the neurotransmitter released from the hair cells of the Organ of Corti are captured in nerve fibres which synapse on ? neurones with their cell bodies in the ?

A

Bipolar / spiral ganglion

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17
Q

The more hair cells in the Organ of Corti bend, the more they what?

A

Fire APs

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18
Q

Complete the sentence: the ? hair cells in the auditory system are more numerous and can be known as the ?

A

Outer / cochlear amplifier

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19
Q

Sensory afferents travelling in CNVIII project to which nuclei in the brainstem?

A

Cochlear and olivatory nuclei

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20
Q

After reaching the cochlear and olivatory nuclei, sensory afferents in CNVIII travel via where to where?

A

Inferior colliculus and thalamus / medial geniculate body

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21
Q

Where are the final destinations of sensory afferents in CNVIII?

A

Auditory cortex and association areas in the sensory cortex

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22
Q

What happens to right and left ear information at the brainstem?

A

The information is mixed

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23
Q

Which structure(s) of the vestibular system are responsible for detecting head angular acceleration, and hence head rotation?

A

The semicircular canals

24
Q

Which structure(s) of the vestibular system are responsible for detecting head linear acceleration, and hence translational motion and gravity (tilt)?

A

Saccule and utricle

25
What are the 3 main components of the vestibular system?
Peripheral sensory apparatus / central processing system / motor output system
26
Complete the sentence: the peripheral sensory apparatus (vestibular organ) detects and relays information to the ? nucleus about head angular and linear velocity to a central processing system. This orientates the head with respect to ?
Vestibular / gravity
27
Complete the sentence: in the vestibular system, the central processing system processes information in conjunction with other ? inputs for position and movement of head in space
Sensory
28
Complete the sentence: in the vestibular system, the motor output system generates compensatory ? movements and compensatory ? movements during head and postural adjustments
Eye / body
29
Complete the sentence: in the semicircular canals are ? fluid filled canals at ? angles to each other, 1 for each major ?
Three / right / plane
30
Complete the sentence: within the dynamic labyrinth of the semicircular canals, the ? detect acceleration and angular head changes. Each ? contains a ? which is fluid filled and contains a gel like ? within which lie the ? of sensory cells. When the head moves, movement of the fluid bends the ? and this activates the hair cells
Ampullae / ampulla / crista ampullaris / cupula / cilia / cilia
31
Which structure in the semicircular canals gets displaced to cause displacement of the cilia of sensory cells?
The cupula
32
Complete the sentence: the otolith organs contain the ?, specialised epithelial hair bearing cells that protrude into a gel like substance which contains ? embedded on its surface.
Macula /otoconia (ear stones)
33
What happens when the ear stones are moved by gravity?
The gel which they are embedded in moves, and this activates the hair cells
34
What are otoconia made of? Where are they found?
Calcium carbonate / otolithic membrane
35
Sensory afferents from the dynamic and static labyrinths form what structure? This merges with the cochlear nerve to form what?
Vestibular nerve / CNVIII
36
From a vestibular aspect, CNVIII travels to which nucleus, where?
The vestibular nuclei in the brainstem
37
Complete the sentence: from the vestibular nerve, the ? carry information via the ? to the ? and ? for proprioceptive integration
Vestibulospinal tracts / thalamus / parietal cortex / cerebellum
38
What clinical sign can be seen due to alternating slow and fast eye movements induced by excessive head rotation in the vestibulo-ocular reflex?
Nystagmus
39
Nystagmus in the absence of what would be abnormaL?
Head rotation
40
What are some drugs which can cause ototoxicity?
Aminoglycosides e.g. gentamycin and some chemotherapy agents
41
Complete the sentence: in the eye, light is focussed onto the ? which is a multi-layered structure containing ?
Retina / photoreceptors
42
What are the two types of photoreceptors in the eye?
Rods and cones
43
Cone photoreceptors are centred where?
In the macula and fovea
44
What is the macula and fovea?
The centre point of the retina where light is focussed
45
Complete the sentence: visual vascular supply and sensory afferents converge at the ? - this part of the retina contains no rods or cones so it is termed the ? - this lies ? to the macula
Optic disc / blind spot / medial
46
What is the direction of the signals in the retina?
Photoreceptors, bipolar neurones, ganglion cells
47
Describe the 3 different colours picked up by the cones in the retina, from shortest wavelength to longest wavelength?
Blue, green, red
48
How is colour blindness usually inherited?
X linked
49
Which nerve FIBRES cross over at the optic chiasm?
Nasal fibres (temporal fields)
50
Complete the sentence: nerve fibres from the ? half of each retina cross over at the ? - the resulting two ? allow right and left visual fields to reach the right and left ? respectively
Nasal / optic chiasm / optic tracts / hemispheres
51
The entire visual field is mapped precisely onto where?
The primary visual cortex in the occipital lobe
52
The visual pathways carry sensory information from where to where?
Retina to the visual cortex
53
Complete the sentence: afferent neurones exiting the optic disc form the ? which travels to the ?
Optic nerve / optic chiasm
54
The optic tracts project from where to where?
Optic chiasm to the lateral geniculate nucleus in the thalamus
55
The optic radiations project from where to where?
The thalamus to the visual cortex
56
What structure is involved in producing the accomodation reflex?
The ciliary muscles (controlling the lens)