Some causes of liver dysfunction

Question 1

Briefly describe Hepatitis

Answer 1

Hepatitis is an inflammatory disorder that involves inflammation and damage to hepatocytes

Question 2

Briefly describe Cholestasis and name the two types

Answer 2

When blood is unable to flow from the liver to the duodenum. Intra-hepatic and extra-hepatic

Question 3

Briefly describe • Cirrhosis

Answer 3

A result of an inflammatory disease involving the liver

Question 4

Name 4 causes of liver dysfunction

Answer 4

hepatitis , cholestasis , cirrhosis and Hepatocellular Carcinoma

Question 5

Name some of clinical marker from a physical exam that can be symptom of liver disease

Answer 5

Skin
• Jaundice
• Oedema
• Abdomen
• Liver abnormalities
• Spleen enlargement
• Eyes
• Other findings.
• Nail changes.
• Testicular atrophy

Question 6

Name some factors that could predispose liver disease

Answer 6

Family History
toxin exposure 
weight loss
Jaundice 
Bleeding from nose , gums ,skin or gut
confusion or poor sleep

Question 7

Name some the acute and chronic signs of hepatitis

Answer 7

Acute: EB, Rubella ,Hep A B C, alcoholic , drugs and toxins
Chronic: Persistent and active

Question 8

Name some of the signs of intra-hepatic cholestasis and extrahepatic?

Answer 8

In intrahepatic cholestasis the secretion of bile is impaired due to hepatitis or due to toxins or primary biliary cirrhosis

Extrahepatic-  obstruction of the flow of the bile
due to gall-stones, malignancy, inflamation of the bile duct,
biliary atresia (condition that inflames bile ducts and only effects infants.