Somatosensory Receptors Flashcards
What is an encapsulated receptor?
Sensory terminations are surrounded by a connective tissue capsule
Capsule and associated structures alter the transmission of stimulus energy
What are free nerve ending receptors?
Bare terminals of myelinated and unmyelinated axons that contact the epithelium
Functionally distinct categories: mechanical or thermal, itch receptors, nociceptors
What is a merkel ending?
Disk-shaped terminal of myelinated axons that contact merkel cells
Merkel cells contain vesicles that mediates signaling from merkel cell to axon ending
Mechanoreceptors
What is a hair follicle receptor?
Terminals of myelinated axons wrap around the base of the hair
Mechanoreceptors
What are the general features of encapsulated receptors?
Contain mechanoreceptors
Pressure applied to the skin is transmitted through the capsule to the axon endings
Describe Meissner corpuscles.
Contain layered stack of Schwann cells
Axon ending wind between the Schwann cell layers
Located just under epidermis in hairless skin
Mechanoreceptors
Describe Pacinian corpuscle
Subcutaneous
Capsule contains concentric layers of epithelial cells with fluid filled spaces
Single axon at the center
Mechanoreceptors
Describe Ruffini endings.
Located in dermis, subcutaneous, and connective tissue
Capsule contains collagen strands with intertwined axon endings
Stretching of skin applies tension to collagen strands, squeezing axon endings – direction dependents
Mechanoreceptors
What types of receptors are rapidly adapting?
Pacinian and Meissner corpuscles
Determined by capsule physical properties
Hair follicle receptors
How do Pacinian corpuscles rapidly adapt?
Capsule transmits pressure onset, but layers forming capsule quickly rearrange and dissipate forct
When pressure is withdrawn capsule layers “rebound”, deforming membrane of axon ending
When do Pacinian corpuscles respond best?
When pressure is changing rapidly
Most sensitive to fast vibrations
What is a tuning curve?
Threshold intensity vs. frequency
A receptor is most sensitive at frequency where the threshold intensity is lowest
What are the slowly adapting receptors?
Merkel
Ruffini
Free nerve endings
What is the only high threshold receptor?
Free nerve endings that function as mechanoreceptors
Where are receptive fields smallest? Largest?
Smallest - digits of hand
Largest - Trunk and limbs