Somatosensory Flashcards

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1
Q

What are the 4 sensory pathways?

A

Fine Touch (discriminative)
Proprioception
Pain
Temperature

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2
Q

Touch : Stimulus? Receptor? Sense Organ?

A

Mechanical deformation
Skin Mechanoreceptors
Pacinian Corpuscle

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3
Q

Proprioception : Stimulus? Receptor? Sense Organ?

A

Mechanical Deformation
Mechanoreceptors
Muscle Spindl, Golgi Tendon Organs, Joint Receptors

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4
Q

Temperature :Stimulus? Receptor? Sense Organ?

A

Thermal Energy
Hot/Cold Thermoreceptors
Nerve Endings in Skin

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5
Q

Pain :Stimulus? Receptor? Sense Organ?

A

Noxious Stimulus - extreme mechanical, thermal, chemical energy
Nociceptors - Mechanoreceptive, thermal, chemoreceptive, polymodal
Nerve endings in the skin

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6
Q

What is Adequate Stimuli?

A

Differential sensitivity of sensory receptors

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7
Q

What is a Pacinian Corpuscle?

A

Rapidly Adapting Mechanorecptor
Depolarization occurs via stretch-activated Na+ channels
Detects mechanical pressure vibrations of 200-300Hz

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8
Q

What is Receptor Potential?

A

The depolarizing or hyper polarizing response to a sensory stimulus

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9
Q

Other Sensory Receptors

A

Hyperpolarization is due decreased Na current (photoreceptors) or increased K+ current (auditory mechanoreceptors)

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10
Q

Stereotypic encoding of stimulus intensity

A

The intensity of the stimulus in encoded by the frequency (number per time) of action potentials (AP)

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11
Q

What is frequency code?

A

Temporal Summation: increase in AP frequency of a single fiber associated with the sensory receptor

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12
Q

What is population code?

A

Spatial summation of is when more sensory receptors and their fibers are activated and Fire APs

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13
Q

What is Transduction?

A

The process of changing physical energy into electrical signals

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14
Q

What is a generator potential for transduction?

A

Change in membrane potential of the sensory receptors, caused by stimulus; may be depolarization (mechanoreceptors) or hyperpolarization (photoreceptor)

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15
Q

What is a first order neuron?

A

The first neuron to fire an action potential after stimulation

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16
Q

Labeled Line Code of Sensory Modality

A

Quality of the Stimulus is encoded by pathway of transmission
- quality = modality = sensory channel

17
Q

What is a sensory modality?

A

A communication channel that is associated with individual senses e.g. Touch, smell, vision

18
Q

What is Adaptation?

A

Nerves adjust to repetitive stimuli

19
Q

Hyperalgesia

A

Heightened sensation of pain - Endogenous chemicals (prostaglandins) from damaged tissue directly activate or sensitize (lower activation threshold) nociceptors. Others are histamine, substance P, serotonin, and bradykinin

20
Q

Neuralgia

A

Severe persistent pain in the distribution of a spinal or cranial nerve. Trigeminal neuralgia is treated by: tractotomy, injection of alcohol into the Trigeminal nerve, oral anticonvulsants

21
Q

Thalamic Pain Syndrome

A

Lesions of Posterior Thalamus

22
Q

Peripheral Neuropathy

A

Numbness and ulcers in limbs often seen in diabetic patients (stocking glove). Mechanism not well understood.

23
Q

Referred Pain

A

Pain arising from deep visceral structures is felt at sites at the periphery of body.

24
Q

Phantom Limb Pain

A

Limb removal leads to sensation of pain in missing limb

25
Q

Analgesia

A

Inability to feel pain while still conscious

26
Q

Sedation

A

A sedative is a drug that calms a patient down, easing agitation and permitting sleep, reducing irritability. Sedatives depress cardiovascular and respiratory functions, cannot be used with alcohol, and can become additive

27
Q

Anesthesia (A State of Unconsciousness)

A

Has three components:

  • analgesia: pain relief
  • amnesia: loss of memory
  • immobilization
28
Q

Hereditary Sensory Autonomic Neuropathy Type 5

A

Loss of ability to feel pain, heat, or cold. Loss of deep pain perception - unable to feel broken bone, ligaments or muscle