Solutions Flashcards by Emme Gilchrist

antimicrobial quality of care system

Must be safe for the eye and effective against killing organisms.
Can be a preservative- resists growth in solution or a disinfectant- eliminates germs from lenses.

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Thimerosal

Methyl based preservative
Small and causes allergic reactions
Not used much anymore

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Chlorhexidine

Kills bacteria, not fungus
Preservative and disinfectant.
Small, causes allergies.

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PHMB

Similar to Chlorhexidine BUT Larger molecule.

Kills bacteria, not fungus

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Biguanides

Smilar to Chlorhexidine. Kills bacteria, not fungus.

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Polyquad/polyquaternium

Kills bacteria, not fungus.

large molecule.

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H202

Kills bacteria and fungus and acanth trophes

Penetrates lens matrix and causes bubbles to form

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Aldox (brand)

Kills bacteria and fungus.

Gave optic free stand alone approval for no rub

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BAK

Not used on soft lenses. Binds and is toxic in eye wash.

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EDTA

Chelating agent. Binds metal ions needed for growth. Good gram neg coverage.

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Cleaning ability of a solution

Removes debris/microorganisms

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5 types of cleaning agents

Surfactants- forms micelles 
Poloxamine 
Pluronic 
Sodium Citrate 
Isopropyl alcohol- kills active and inactive acanth.

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Protein removers (3 types) aka enzyme products

Pancreatin, substiliin A, papain

Traditionally used 1x per week
Tablets, vials, saline or MPS. Newer products- liquid drops.

poor compliance bc cumbersome to use.

***RINSE lens with saline prior to putting in eye. After soaking!

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Pros and cons to heat disinfection

Great disinfection and cheap (uses saline while heating)

Cannot heat group 4 and cooks proteins onto lens- they don’t last as long.

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There are 3 optifree solutions (alcon)

Optifree express
Optifree replenish
Optifree puremoist

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Opti free express
2 preservatives
1 cleaner

Polyquad and aldox

Sodium citrate cleaner

Opti free repleniSH

Developed for silicone hydrogels.
TearGlyde attracts moisture to the lens surface.
This is a polar molecule- hydrophobic part attaches to lens, hydrophilic part attaches to water.

Optifree pure moist

Further refinement of RepleniSH

Tear glyde AND hydraglyde wetting agents.

Blink RevitaLens (J and J)
3 preservatives
1 lubricant/cleaner

Biguanide, polyquad, EDTA.

Tetronic surfactant cleaner.

**effective against acanth cysts !

Complete (J and J)

2 preservatives

PHMB, EDTA
“easy rub”
No wetting agent bc it created biofilm in the past.

ReNu advanced (b and L)

3 preservatives
2 moisture agents

Biguanide, polyquad, alexidine (biguanide)

Moisture agents to help w comfort- poloxamine, poloxamer 181

BioTrue (b and L)

-2 preservatives

Biguanide and polyquad

Bio inspired- lubricant, matches 7.5 pH of tears, keeps lysozymes intact (natural protective proteins on eye)

Clear Care Alcon

1 bottle peroxide system
Surfactant cleaner in peroxide
Rinse lenses in basket for 5 seconds w clear care then soak for 6 hours

GP ok but must rub, no conditioning agent.

Oxysept (J and J)

one bottle peroxide system 
Surfactant cleaner in peroxide 
Rinse lenses in basket for 5 seconds w oxysept, then soak. 
**ADD neutralizing tablet 
Turns pink when done

GP Ok, must rub

Boston Simplus (B and L)

RGP MPS Chlorhexidine and PHMB Rub after soak!!!! Rinse- soak- rub Good protein removal

Is Chlorhexidine safe for soft and hard CLs?

Small so will attach to soft CL and cause allergic rxn. Safe for GPs- will not attach.

Unique pH (Menicon)

RGP MPS Polyquad and EDTA Adjustable viscosity based on pH of tears. Less viscous than boston. Cannot buy in local stores

Boston Original

Cleaner and conditioner Cleaner is abrasive to silicone. Not good for soft/high Dk lenses. Conditioner is viscous to increase gettability. Preservatives include chlorhexidine and EDTA *cannot use this on any lenses coated with hydra peg

Ultrazyme (j and J)

``` Subtilisin A Weekly product PEROXIDE SYSTEM 1 tablet in basket MUST rinse lens prior to insertion. Need saline! ```

Boston Liquid Enzyme

Subtilisin A Weekly product for GPs 2 drops in each well. Must rinse lenses prior to insertion.

Progent (menicon)

GP Bi weekly cleaner Bleach and KBr mixed Rinse before putting in eye

When to use PF saline

Scleral

Generic solutions are/arent the same as brand

Are not the same!!