Solution Dosage Forms [Dr Green]

Question 1

Define: Solution

Answer 1

A liquid mixture in which the minor component (solute) is uniformly distributed through the major component (solvent)

Question 2

List 4 types of solution

Answer 2

Syrups
Elixirs
Spirits
Aromatic water

Question 3

List 4 solvent vehicles

Answer 3

Water - most widely used
Alcohol
Glycerol (glycerin)
Propylene glycol

Question 4

List 4 excipients

Answer 4

Buffers
Viscosity enhancers
Preservatives
Colours

Question 5

What is the role of viscosity enhancers?

Answer 5

Improve pouring quality

Question 6

Name an example of a preservative that can be added to a solution

Answer 6

Methyl or propyl parabens

Question 7

List 3 advantages of solutions as an oral dosage form

Answer 7

Easy to swallow
Fast therapeutic response - immediately available for absorption
Homogeneous (single phase)

Question 8

List 3 disadvantages of solutions as an oral dosage form

Answer 8

Bulky
Micro-organism growth - preservative needed
Issues with accuracy of dose - spoon use