Solubility Flashcards
1
Q
Poor solubility/dissolution can affect
A
High-throughput screening (HTS ) assays
* The ability to achieve efficacious and toxicologically
relevant exposures in animals.
* The bioavailability of the drug from the formulation.
* Possibility of increased “food effect”
* Inability to provide liquid formulations e.g injections ,
paediatric / geriatric dosage forms