Soft Tissue Tumors Flashcards

1
Q

What is a lipoma/liposarcoma?

A

A lesion with very atypical cells and lipoblasts (atypical cell with bizarre nucleus and vesicles of lipid in the cytoplasm) - this is the strangest definition ever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is nodular fasciitis?

A

Rapidly growing, small, benign, fibrous proliferation on the subcutis; prevalent in young adults and presents with a history of rapid growth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is Myositis Ossificans?

A

Reactive bone formation in muscle as a result of injury; woven bone in granulation tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Is myositis ossificans benign?

A

Yes but it can mimic neoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How does myositis ossificans occur?

A

Usually from blunt trauma, often in lower limb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Where is the woven bone of myositis ossificans prevalent?

A

In the periphery; immature at center, and late stages can contain cartilage/lamellar bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is superficial fibromatosis?

A

Small lesions of the hand, feet, and penis; occur in young males; arise in digits of infants and children and are characterized by peculiar inclusion like condensations of cytoplasmic action

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is characteristic of superficial fibromatosis?

A

Dupuytren contraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is deep fibromatosis?

A

Rare condition in which tumors are large, and local control is hard to achieve; they dont metastasize. In females in late 20’s it ail be in the abdominal wall; later on it will be fewer abdominal tumors and no sex predominance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is a fibrosarcoma?

A

A tumor of mesenchymal cell origin that is composed of malignant fibroblasts in a collagen background; can occur as a soft tissue mass or bone tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Are fibrosarcomas painful? where in the bone do they occur?

A

Yes, and in the metaphysis of long bones and pelvis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

At low power, what do fibrosarcomas demonstrate?

A

A herringbone pattern

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is a dermatofibroma?

A

A.k.a. fibrous histiocytoma and due to non-cancerous growth of dermal dendritic histiocyte cells; in some cases due to minor injury; cause is unknown

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where do dermatofibromas occur and how do they look?

A

Legs and arms and once they develop they persist for years; appear as firm nodules, often yellow-brown, sometimes pink and sometimes dark

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is dermatofibrosarcoma protuberans?

A

DFSP is relatively uncommon soft tissue neoplasm with intermediate to low grade malignancy; it is a locally aggressive tumor with high recurrence rate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is malignany fibrous histiocytoma?

A

MFG is controversial; accounts for about a quarter of soft tissue sarcomas; it contains both fibroblast and histiocyte like cells in varying proportions with spindled and rounded cells exhibiting storiform arrangement

17
Q

What is a rhabdomyosarcoma?

A

A fish flesh like white tumor made up of cancerous muscle cells called rhambdomyoblasts; they can arise in any muscle

18
Q

What are most common sites for rhabdos?

A

Adjacent to the base of skull, around the eye, head and neck (nasopharyngeal), arms and legs, urinary system and repro tract

19
Q

What cells are rhabdos usually made up of?

A

Bizarre elongated strap cells

20
Q

What is a leiomyoma?

A

Neoplasm of smooth muscle, most common site is uterus; their etiology is unknown, they affect 25-40% of women in child bearing age, and are usually asymptomatic, only removed if painful, can be anywhere b/c smooth muscle is everywhere

21
Q

What cell is typical of leiomyomas?

A

“cigar” shaped cells

22
Q

What is a leiomyosarcoma?

A

Can arise anywhere in the body, more common in uterus abdomen, or pelvis; not much other info given except survival based on histological grade; size and invasiveness

23
Q

Why do sarcomas met to the lung so easily?

A

They travel through the blood stream, not lymph; pulm mets major cause of mortality for all sarcoma patients (not just leiomyosarcoma)