Soft tissue sarcoma Overview Flashcards
1
Q
Describe soft tissue sarcomas?
A
- Rare
- 7000 new cases /pa in US
- Proper evaluation crucial
- unplanned excision may have neagtive effect on outcome
- delay in dx can -> affect outcome
- Metastatsis
- Lung common site
- Prognosis
- poor =
- High grade
- Size >5cm
- tumour location below deep fascia
- poor =
2
Q
Describe some types of sost tissue sarcomas?
A
- > 50 types
- Routine tested
- Synovial sarcoma
- Liposarcoma
- Rhabomyosarcoma
- Fibrosarcoma
- Leiomyosarcoma
- angiosarcoma
3
Q
How do soft tissue sarcomas present?
A
- Painless enlarging Mass
O/E
- Palpable soft tissue mass
- above/below fascia has diagnostic importance
- size >5cm = poor prognostic sign
4
Q
What is seen on MRI?
A
- Mandatory to evaluate soft tissue
- MRI diagnostic for benign lesions=
- lipomas
- Neurilomoma ( schwanoma)
- Intramuscular myxoma
- If diagnostic and mass is benign it can be removed without biopsy
- interdeterminate biopsy or suggestive of sarcoma= core needle biopsy/open biopsy
- soft tissue sarcomas can look like similar to haematomas so cautious when haematoma without trauma- do open biopsy if haematoma on core needle biopsy ;)
5
Q
Describe the tx of Soft tissue sarcomas?
A
- tx must be based on tissue dx unless images diagnostic
Operative
-
Radiation therapy & wide surgical resection
- standard care most pt
- radtx= adjunct reduce local reoccurrance
- 50-60 Gy standard dose
- Give Pre/POst op
- pre- assoc 30% wound complx
- post op > radiation indiced morbidity & increased risk of radiation induced sarcoma
- Chemo is contraversial for Soft tissue sarcomas
- Surgical resection must confirm border free of disease other wise ** tumour bed re-excision as this is the most important tx related factor **
6
Q
What are the complications of surgical resection of soft tissue sarcomas?
A
- Reoccurrance
- locally
- low grade soft tissue sarcoma
