Sodium Hypo...

Question 1

Who used it during 1st WORLD War n in what form?

Answer 1

DAKIN… n in 0.5% conc. (Buffered with Bicarbonate)

Question 2

Milton’s solution?

Answer 2

1% Sodium hypo…

Pn - mil TON - means a Hundred! means 1. (1.00%)

Question 3

Who introduced it into Endo?

Answer 3

COOLIDGE

Pn – Endo irrigants r COOL!! (COOLIDGE)

Question 4

Mechanisms of action-

Answer 4

1 - Saponification —- Fatty Acids —–》fatty acid salts + glycerol

2 - Hypochlorous acid formation —–》 Liberates Chlorine + H+ (neutralizes bact)

3 - Deamination reaction

4 - High pH - reduced bact. Metabolism

A Special Point - Chlorine liberated is consumed within 2 min… So frequent replenation required…

Question 5

Adv -

Answer 5

Is an antiseptic + Disinfectant + sterilizing solution…
Is a bleaching agent… by the release of NASCENT O2
A potent tissue solvent…
Lubricating action…

Question 6

Disadvantages-

Answer 6

• Can’t remove the smear layer alone… but does when combined with CHX..
• Can’t dissolve INorganic components.
• Though a bleaching agent, contacts with RBCs ——> Hemolysis —–> Dentin discoloration… Also, difficult to remove from RC walls since it crystallizes…
• Hazardous due to its tissue dissolving property…
  Immediate C/F - Pain
  Swelling
  Ecchymosis

Long term features -

• Parasthesia
• muscle weakness
• scarring

—–> Rx - IM steroids, Abiotics, Analgesics… If needed surgical intervention with wound debridement…

Question 7

NaOCl n CHX used alternatively.. How?

Answer 7

Main adv - Effervescent action…
FINALLY HYPO should be used before closing!! Because, if CHX used, ——-> reacts with blood n pulp debris —–> Surgical emphysema! ——> tooth pain!!

Question 8

Effective against?

Answer 8

G posi, G nega, virus, yeast…