SOC

Question 1

What does the MSO do?

Answer 1

Responsible for sensitivity to ITDs

Question 2

What are the main inputs to MSO?

Answer 2

AVCN

Question 3

What type of cell is MSO?

Answer 3

Mostly EE

Question 4

What does the LSO do?

Answer 4

Responsible for sensitivity to ILDS

Question 5

What are the main inputs to LSO?

Answer 5

Direct excitatory from spherical bushy cells in ipsilateral AVCN

Indirect inhibitory inputs from globular bushy cells in contralateral AVCN via the MNTB

Question 6

What time of cell is LSO?

Answer 6

Mostly EI

Question 7

Explain the tonotopic organization of the MSO.

Answer 7

Overrepresentation of low frequency

Lateral aspect tuned to low frequency sounds, as you move medially the CFs become higher

Question 8

Explain the tonotopic organization of the LSO.

Answer 8

Overrepresentation of high freq

High frequencies are represented towards the ventral end, lower frequencies represented at the dorsal end

Question 9

Are MSO neurons tuned to ITD or IPD? Why?

Answer 9

ITD- because independent of frequency (phase doesn’t matter)

Firing rate as a function of interaural delay
Best delay independent of frequency

Question 10

Rank order the following in terms of firing rate at relatively large levels for an MSO neuron: ipsilateral, contralateral, bilateral.

Answer 10

Binaural (most) → contra → ipsi

Question 11

Draw firing rate as a function of ITD for the MSO.

Answer 11

Number of spikes (y)
ITD (x)
looks like sine tone

Question 12

Draw firing rate as a function of ILD for the LSO.

Answer 12

Number of spikes (y)
ILD (x)

looks like cliff