SNP+Elimination reactions

Question 1

the order of carbocation stability generally proceeds

Answer 1

tertiary > secondary > primary

Question 2

polar protic vs polar aprotic

Answer 2

Polar protic solvents are the compounds containing OH or NH group that is able to form hydrogen bonds. Polar protic solvents are highly polar because of the OH or NH group. Polar aprotic solvents is a group solvents with medium range of polarity. They are polar because of polar bonds like C=O.

Question 3

compare SN1 and SN2

alkyl halide+nucleophile ability+Solvent

Answer 3

Question 4

Rate of formation

Answer 4

0, 0.1, 2,100

Question 5

Rate of formation

Answer 5

1

Question 6

Rate of formation

Answer 6

91

Question 7

Rate of formation

Answer 7

7,700
130,000

Question 8

When you have a sp and sp2 electrophile,

Answer 8

You can not do any of SN/E (1-2) reaction

Question 9

Leaving group formation for E2

Answer 9

Good leaving group- internal double bond
bad leaving group- external double bind
primary H is more likely to be extracted for bad leaving group E2 due to built up of charge from LG not wanting to leave

Question 10

For SN2 its best to use a —— solvent because

Answer 10

polar aprotic solvent becaus it doesnt trap our nucleophile or H bond with it

Question 11

SN1 perfer—- carbons

Answer 11

tertiary

Question 12

For E2 reaction what is the conformation of the reactants?

Answer 12

Antiperiplanar

Same plane and 180 degree - LG and the H for the base

Question 13

In E reactions, what H is leaving?

Answer 13

beta

Question 14

Best leaving groups

Answer 14

Question 15

Good nucleophile ranking

Answer 15

Question 16

How to know if you have a good leaving group

Answer 16

conjugate base of strong acid

Question 17

acetone is a —- solvent

Answer 17

aprotic

Question 18

h2so4 is a —- solvent

Answer 18

protic

Question 19

More reactive bases promote — reactions

Answer 19

E2