Smoking (Various PDFs)

Question 1

What is Chantix used for?

Answer 1

Smoking cessation

Question 2

Patients should know to stop taking Chantix immediately if they notice…

Answer 2

Mood/behavior changes
Confusion
Anxiety
Panic attacks
Hallucinations
Extreme fear
Aggression
Impulsive
Agitation
Hostility
Suicidal ideation

Question 3

Interaction of smoking with caffeine

Answer 3

#Increased metabolism (induction of CYP1A2); clearance decreased by 56%
#Caffeine levels may increase after cessation

Question 4

Interaction of smoking with fluvoxamine

Answer 4

#Increased metabolism; clearance increased by 25%; plasma concentration decreased by 47%
#Dosage modifications not routinely recommended, but smokers may require higher dosage

Question 5

Interaction of smoking with olanzapine

Answer 5

#Increased metabolism; clearance increased by 40-98%
#Dosage modifications not routinely recommended, but smokers may require higher dosage

Question 6

Interaction of smoking with oral contraceptives

Answer 6

#Increased risk of cardiovascular adverse events (stroke, MI, etc) in women who smoke & use oral contraceptives
#Risk increases with age & heavy smoking
#Risk is quite marked in women over 35

Question 7

Interaction of smoking with tacrine

Answer 7

#Increased metabolism; half-life decreased by 50%
#Serum concentrations 3x lower
#Smokers may require higher dosages

Question 8

Interaction of smoking with theophylline

Answer 8

#Increased metabolism: clearance increased by 58-100%
#Half-life decreased by 63%
#Theophylline levels should be monitored if smoking is initiated, discontinued, or changed
#Maintenance doses considerably higher in smokers

Question 9

What are some cognitive strategies for smoking cessation?

Answer 9

1) Review commitment to quit
2) Distractive thinking
3) Positive self-talks
4) Relaxation through imagery
5) Mental rehearsal & visualization

Question 10

What are some behavioral strategies for smoking cessation?

Answer 10

1) Anticipate stress
2) Limit or abstain from alcohol during early stage of quitting
3) Avoid prolonged contact with smokers
4) Have non-tobacco oral substitutes readily available
5) Anticipate routines associated with smoking & change them
6) Be aware of post-cessation weight gain & plan for it
7) Be aware that cravings are temporary