Smoking cessation Flashcards
Smoking is:
the most preventable cause of death in our society
Second hand smoke (SHS):
>contains more than 7,000 chemicals with >50 chemicals that cause cancer >no such thing as no risk free exposure >46,000 adults die from CVD each year >3,400 die from lung cancer >SHS from 1 cigar = 1 pack of cigarettes
Environmental tobacco smoke (ETS) and children:
> 32 million ages 3-11 are exposed daily
25% of children live with 1 adult smoker*
30% high risk for respiratory diseases
150,000-300,000 new cases of bronchitis & pneumonia for 34% high risk of lung cancer by adulthood
increase in the # of asthma attacks & severity of symptoms in 200,000 to 1 million kids
Third-hand smoke:
toxic residue from tobacco smoke that remains after a cigarette is extinguished (clothes, furniture, ect.)
Chemicals in tobacco and smoke:
300 chemicals ignited leads to >7000 chemicals such as: formaldehyde, arsenic, cyanide, DDT, lead, radioactive materials, ammonia, acetone, hexamine, mercury, CO, nitrous oxide, nitrobenzene, cadmium, butane, vinyl chloride, hydrogen cyanide, and steric acid.
Nicotine:
psychoactive drug in tobacco products, most common form of chemical dependence in U.S., as addictive as heroin, cocaine, or alcohol. usually takes 10 attempts to quit.
Ammonia used to treat tobacco:
allows nicotine to be absorbed 100x more readily than tobacco in its’ natural state.
What happens with nicotine when a person smoke?
onset: immediate>6-10 seconds to hit the brain
peak: 5 min.
duration: 5-15 min.
half-life: 2 hrs
withdrawl: 3-4 hrs
Amount of nicotine absorbed:
> 1ppd = 20 cigarettes, x10 puffs.
200 puffs/day x 7 days = 1400 puffs/week
1-3.5 mg per cig. (20-70 mg/pk)*
1-20 mg per cigar (varies with the size)
Averages for cigarettes depends on brand:
reg = 1.2-3.5 mg
light = 1 mg
>individuals adjust how they smoke depending on whether its a light or regular cigarette
E-cigarettes (e-cigs):
> nicotine inhalation devices
FDA has classified them as drug-delivery device
more than 200 companies manufacture the devices
about 1 in 5 adult smokers of traditional cigarettes in US have tried e-cigarettes
current research: do they help smokers quit?
Absorption of nicotine:
stimulates the release of multiple neurotransmitters:
>dopamine*- pleasure & reward
>acetylcholine- cognitive enhancement, arousal
>norepinephrine- appetite suppression, arousal
>glutamate- learning & memory enhancement
>b-endorphins & g-aminobutyric acid - decrease anxiety & tension
>serotonin- mood modulation, appetite suppression
*w/in seconds of first puff, “feel good” pathway occurs
Physical effects of nicotine:
Increased: arousal, alertness, HR/BP, cutaneous vasoconstriction, gastric motility, cardiac outpt, peripheral vasoconstriction, and platelet adhesion.
decreased: appetite
Direct effects of cigarette smoking:
> hyperplasia of cells
*goblet cells = increased mucous production
*reduces airway diameter
*reduces ciliary activity
*abnormal dialation of distal airways
*large atypical nuclei develop
changes in small airway function
decreased oxygen carrying capacity on Hgb
effects of tobacco smoke on the respiratory system
Passive smoking (ETS):
secondhand smoke (SHS) -
>decreased pulmonary function
>increased respiratory symptoms
>severe lower respiratory infections (adults & kids)
>increased lung and nasal sinus cancer
>increased number of gene mutations (immune cells in newborns) similar to those associated with childhood cancers