SMB Week 2 Flashcards
Nevis typically appear during what age range?
In the first 3 decades of life
When do seborrheic keratoses typically appear?
During and after the 4th decade of life
A variant of SKs, these are small, hyper pigmented, sessile to filiform, smooth-surfaced papules appearing on the face and temples darker skin types.
Dermatosis Papulosa Nigra
Another name for skin tags
Acrochordons
Complication of removing SKs in darker skinned patients.
Dyspigmentation. Hyper pigmentation with curettage, hypo with liquid nitrogen.
What is the definitive treatment for an inflamed epidermal inclusion cyst?
I & D (but don’t excise due to risk of infection)
Where are melanocytes located?
- In the basal layer of the epidermis
- In the matrix portion of the hair bulb
What is an “epidermal melanin unit?”
A melanocyte together with the 36 keratinocytes it’s dendrites supply.
Two types of melanin:
- Eumelanin
- Pheomelanin
Melanin production is mediated by what enzyme?
Tyrosinase
Variations in skin color are due to what 3 things?
Number, size and aggregation of melanosomes
Which grouping of melanocytes is associated with darker skin, aggregated or non-aggregated?
Non-aggregated
Which form of contact dermatitis is concentration dependent?
Irritant contact dermatitis (ICD)
Which form of contact dermatitis involves papules prior to the formation of vesicles?
Allergic contact dermatitis (ACD)
Which form of contact dermatitis tends to have well-defined borders?
ICD
What are some of the features of chronic ICD?
- Mostly appears on hands
- Hyperkeratosis, scaling and fissures
- Ill-defined borders and lichenification
What type of eczema has “tapioca”-like vesicles?
Dishidrotic eczema
What does the phrase “crescendo reaction” refer to?
The worsening of an allergic reaction with repeated exposure to the antigen
What does the phrase “outside job” refer to when describing contact dermatitis?
Often linear, artificial patterns.
Autoantibodies seen in patients with atopic dermatitis
IgE
Some common triggers of atopic dermatitis
- Food
- Clothing
- Seasons (more common in winter)
- Emotional stress
Most common symptom of atopic dermatitis
Itching (it’s often described as “the itch that rashes”)
Type of vesicular eczema seen on the hands and feet
Dishidrotic eczema
Treatment for ICD
- Removal of irritant
- Wet dressings with Burow’s solution
- Topical glucocorticoids