Small and large plaque parapsoriasis

Question 1

Onset of parapsoriasis:

Answer 1

40 y/o

Question 2

What is gender predilection for parapsoriasis?

Answer 2

3:1 M:F

Question 3

Describe lesions of SPP and the classic distribution.

Answer 3

Scaly patches< 5cm in Bathing suit distribution.

Question 4

Which lymphomas is Small plaque PS associated with?

Answer 4

• NONE!

Question 5

A variant of SPP is _____ and presents with _____.

Answer 5

• digitate dermatosis

- long finger-like patches along cleavage lines on the flanks

Question 6

How does Large PPS present clinically and what is distribution?

Answer 6

• scaly patches> 5cm in size in bathing suit distribution

Question 7

What is the clinical course of SPP?

Answer 7

• wax and wane in course the either resolve spontaneously or with treatment after several years

Question 8

Large PPS may progress to _____ with a risk of ____ % in ____ amount of time

Answer 8

• Mycosis fungicides

- 10-35% risk in 6-10 years

Question 9

Variant of Large PPS is _____

Answer 9

• retiform parapsoriasis

Question 10

Retiform parapsoriasis (variant of Large PPS) almost always does what?

Answer 10

• progresses to MF

Question 11

How does retiform parapsoriasis look clinically?

Answer 11

• wide-spread erythematous scaly patches in a net-like distribution

Question 12

How do you diagnose parapsoriasis?

Answer 12

• Biopsy

Question 13

Biopsy of parapsoriasis will show:

Answer 13

• parakeratosis (corresponding to scale clinically)
• mild acanthosis and spongiosis
• mild lymphocytic infiltrate at DEJ, predominantly CD4 +
• may have T-cell clonality

Question 14

Treatment of parapsoriasis?

Answer 14

• topical corticosteroids and various photo therapies

Question 15

pathogenesis of parapsoriasis?

Answer 15

• idiopathic

Question 16

What are symptoms of parapsoriasis?

Answer 16

• asymptomatic!