Slides Flashcards
What is this and why?
Minimal Change Disease - podocyte foot process effacement
What is this and why?
FSGS because only part of the glomeruli is carred, and only some glomeruli are effected
What is this and why?
This is a comparison of normal glomeruli and podocyte foot process effacement in MCD and FSGS
What is this and why?
These are wire loop capillaries that correspond to Membranous Nephropathy
What is this and why?
Membranous Nephropathy with granular IgG deposits
What is this and why?
Membranous Nephropathy due to the spikes and domes in the glomerular basement membrane
What is this and why?
MPGN due to increased cellularity and pronounced “lobularity”
What is this and why?
MPGN, due to increased cellularity and lobulation
How could MPGN Type I and Type II be differentiated?
On the slide alone, you can’t tell - need a stem for IgG + C3 staining (Type I) or C3 (Type II)
What is this and why?
Diabetic Nephropathy, due to the Kimmelstein Wilson lesions in the big pink blob
What is this and why?
Chronic Glomerulonephritis; because there’s a bunch of totally sclerosed Glomeruli
What is this and why?
Post Steptococcal Glomerulonephritis - Starry Sky fluorescnece
What is this and why?
Post Streptococcal Glomerulonephritis, due to subepithelial humps
What is this and why?
Rapidly Progressive Glomerulonephritis on Light Microscopy, due to proliferation of cells, possibly a result of Type I (Anti-GBM/Goodpasture’s) or Type II (Lupus Nephritis) or Type III (MPA/GPA/EGPA)
What type of RPGN is this and why?
Type I RPGN due to the linear deposits, suggesting anti-GBM disease
What type of RPGN is this and why?
RPGN Type II, due to the granular IgG deposits which suggests an immune complex disease like SLE or PSGN with C3 and IgG/A
What type of RPGN is this and why?
This is RPGN Type III, which has no findings on FM or EM but shows up as hypercellularity on LM, due to the thickening of the fibrinoid vessel, suggesting MPA
What type of RPGN is this and why?
This is RPGN Type III, which has no findings on FM or EM but shows up as hypercellularity on LM, due to the thickening of the fibrinoid vessel, suggesting GPA because it is in a glomeruli
What is this and why?
This is IgA nephropathy, since the mesangial tree of the Glomeruli has thickened due to deposition of IgA immune complexes
What is this and why?
IgA Nephropathy due to granular deposition of IgA immune complexes
What is this and why?
Amyloidosis, due to the Congo Red stain showing apple-green birefringence on polarized light
