slide 3 Flashcards

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1
Q

cell division

A

The ability of organisms to produce more of their own
kind distinguishes living things from nonliving matter.
The continuity of life is based on the reproduction of
cells, or cell division

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2
Q

In unicellular organisms,

A

division of one cell

reproduces the entire organism.

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3
Q

Multicellular organisms depend on cell division for

A
  • Development from a fertilized cell
  • Growth
  • Repair
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4
Q

cell cycle

A

the

life of a cell from formation to its own division.

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5
Q

Cell division

A

is a controlled process resulting in

genetically identical daughter cells

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6
Q

Cells duplicate their genetic material

A

before
they divide, ensuring that each daughter cell
receives an exact copy of the genetic code

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7
Q

genome

A

All the DNA in a cell constitutes the cell’s genome

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8
Q

A genome can consist of

A

a single DNA molecule
(common in prokaryotic cells) or a number of DNA
molecules (common in eukaryotic cells)

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9
Q

chromosomes.

A

DNA molecules in a cell are packaged into

chromosomes.

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10
Q

chromatin

A

The combined DNA and protein complex is called chromatin

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11
Q

Every eukaryotic species has a characteristic number of
chromosomes. Chromosomes come in pairs with one of
each pair inherited from each parent

A

Humans have 23 pairs

= 46 chromosomes

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12
Q

sister chromatids.

A

During cell replication each chromosome is duplicated. It is
connected to its copy. These connected copies of the
chromosome are called sister chromatids

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13
Q

The centromere

A

is the narrow “waist” of the
duplicated chromosome, where the two
chromatids are most closely attached

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14
Q

The two sister chromatids separate and move into

two nuclei before the cell divides into two

A

Once separate, the chromatids are chromosomes

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15
Q

Eukaryotes have two types of cells

A

Somatic cells

and gametes

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16
Q

Somatic cells

A

– typical cells of the body, contain the

full genome, the full set of chromosomes

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17
Q

Gametes –

A

reproductive cells including sperm and

eggs, contain half the chromosomes in somatic cells

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18
Q

meiosis.

A

Gametes (sperm and eggs) are produced by a

variation of cell division called meiosis

19
Q

Meiosis yields

A

nonidentical daughter cells that have
only one set of chromosomes, half as many as the
parent cell.

20
Q

The cell cycle of somatic cells consists of

A
  • interphase

- mitotic (M) phase

21
Q

Interphase

A

(cell growth and copying of

chromosomes in preparation for cell division)

22
Q

Mitotic (M) phase

A

(mitosis and cytokinesis)

23
Q

interphase (about 90% of the cell cycle) can be

divided into subphases

A

– G1 phase (“first gap”)
– S phase (“synthesis”)
– G2 phase (“second gap”)
The cell grows during all three phases, but
chromosomes are duplicated only during the S phase.

24
Q

interphase (about 90% of the cell cycle) can be

divided into subphases

A

– G1 phase (“first gap”)
– S phase (“synthesis”)
– G2 phase (“second gap”)
The cell grows during all three phases, but
chromosomes are duplicated only during the S phase.

25
Q

Mitosis

A

the division of duplicated chromosomes

26
Q

Mitosis is conventionally separated into five phases

A
– Prophase
– Prometaphase
– Metaphase
– Anaphase
– Telophase
***Cytokinesis overlaps the latter stages of mitosis.
27
Q

G2 of interphase

A

Chromosomes have been
duplicated but aren’t condensed. Two centrosomes
have formed that will organize the mitotic spindle.

28
Q

The mitotic spindle is

A
a
structure made of
microtubules that controls
chromosome movement
during mitosis.
29
Q

An aster

A

(a radial array of
short microtubules) extends
from each centrosome in
the spindle

30
Q

Prophase:

A

Chromatin is condensed into discrete
duplicated chromosomes that appear as pairs of
identical sister chromatids joined at their centromeres.

31
Q

Prometaphase:

A

Nuclear envelope fragments. Each
of the two sister chromatids of each duplicated
chromosome has a kinetichore protein to which the
microtubules of the spindle attach.

32
Q

Metaphase

A

The chromosomes are aligned at the
metaphase plate, a plane equal distance from the
two centrosomes.

33
Q

Anaphase

A

Sister chromatids of each pair separate
and move towards opposite centrosomes. The cell
elongates as the microtubules not attached to
kinetichores lengthen

34
Q

Telephase

A

Two daughter nuclei form in the cell. The
chromosomes become less condensed. Spindle
microtubules are depolymerized.

35
Q

cleavage

A

In animal cells, cytokinesis occurs by a process

known as cleavage, forming a cleavage furrow

36
Q

In plant cells, a cell plate

A

forms during cytokinesis

37
Q

binary fission.

A

Prokaryotes (bacteria and archaea) reproduce by

a type of cell division called binary fission

38
Q

In binary fission, the chromosome replicates

(beginning at an origin of replication),

A

and the
two daughter chromosomes actively move apart.
The plasma membrane pinches inward, dividing
the cell into two

39
Q

Regulation of the Cell Cycle

A
The frequency of cell division
varies with the type of cell.
These differences result from
regulation at the molecular level.
Cancer cells manage to escape the
usual controls on the cell cycle.
40
Q

cell cycle control system

A

The sequential events of the cell cycle are directed
by a distinct cell cycle control system, which is
similar to a clock.
The cell cycle control system is regulated by both
internal and external controls.
The clock has specific checkpoints where the cell
cycle stops until a go-ahead signal is received

41
Q

Regulation of the Cell Cycle
For many cells, the G1 checkpoint seems to be
the most important.

A

If a cell receives a go-ahead signal at the G1
checkpoint, it will usually complete the S, G2
,
and M phases and divide

42
Q

G0 phase.

A

If the cell does not receive the go-ahead signal, it
will exit the cycle, switching into a nondividing
state called the G0 phase

43
Q

An example of an internal signal is that kinetochores
not attached to spindle microtubules send a
molecular signal that delays anaphase

A

External signals include growth factors, proteins

released by cells that stimulate other cells to divide

44
Q

Cancer cells do not respond normally to the body’s

control mechanisms

A

Cancer cells may not need growth factors to grow
and divide, rather they .
– may make their own growth factor
– may convey a growth factor’s signal without
the presence of the growth factor
– may have abnormal cell cycle control