slide 3 Flashcards

1
Q

cell division

A

The ability of organisms to produce more of their own
kind distinguishes living things from nonliving matter.
The continuity of life is based on the reproduction of
cells, or cell division

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2
Q

In unicellular organisms,

A

division of one cell

reproduces the entire organism.

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3
Q

Multicellular organisms depend on cell division for

A
  • Development from a fertilized cell
  • Growth
  • Repair
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4
Q

cell cycle

A

the

life of a cell from formation to its own division.

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5
Q

Cell division

A

is a controlled process resulting in

genetically identical daughter cells

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6
Q

Cells duplicate their genetic material

A

before
they divide, ensuring that each daughter cell
receives an exact copy of the genetic code

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7
Q

genome

A

All the DNA in a cell constitutes the cell’s genome

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8
Q

A genome can consist of

A

a single DNA molecule
(common in prokaryotic cells) or a number of DNA
molecules (common in eukaryotic cells)

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9
Q

chromosomes.

A

DNA molecules in a cell are packaged into

chromosomes.

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10
Q

chromatin

A

The combined DNA and protein complex is called chromatin

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11
Q

Every eukaryotic species has a characteristic number of
chromosomes. Chromosomes come in pairs with one of
each pair inherited from each parent

A

Humans have 23 pairs

= 46 chromosomes

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12
Q

sister chromatids.

A

During cell replication each chromosome is duplicated. It is
connected to its copy. These connected copies of the
chromosome are called sister chromatids

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13
Q

The centromere

A

is the narrow “waist” of the
duplicated chromosome, where the two
chromatids are most closely attached

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14
Q

The two sister chromatids separate and move into

two nuclei before the cell divides into two

A

Once separate, the chromatids are chromosomes

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15
Q

Eukaryotes have two types of cells

A

Somatic cells

and gametes

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16
Q

Somatic cells

A

– typical cells of the body, contain the

full genome, the full set of chromosomes

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17
Q

Gametes –

A

reproductive cells including sperm and

eggs, contain half the chromosomes in somatic cells

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18
Q

meiosis.

A

Gametes (sperm and eggs) are produced by a

variation of cell division called meiosis

19
Q

Meiosis yields

A

nonidentical daughter cells that have
only one set of chromosomes, half as many as the
parent cell.

20
Q

The cell cycle of somatic cells consists of

A
  • interphase

- mitotic (M) phase

21
Q

Interphase

A

(cell growth and copying of

chromosomes in preparation for cell division)

22
Q

Mitotic (M) phase

A

(mitosis and cytokinesis)

23
Q

interphase (about 90% of the cell cycle) can be

divided into subphases

A

– G1 phase (“first gap”)
– S phase (“synthesis”)
– G2 phase (“second gap”)
The cell grows during all three phases, but
chromosomes are duplicated only during the S phase.

24
Q

interphase (about 90% of the cell cycle) can be

divided into subphases

A

– G1 phase (“first gap”)
– S phase (“synthesis”)
– G2 phase (“second gap”)
The cell grows during all three phases, but
chromosomes are duplicated only during the S phase.

25
Mitosis
the division of duplicated chromosomes
26
Mitosis is conventionally separated into five phases
``` – Prophase – Prometaphase – Metaphase – Anaphase – Telophase ***Cytokinesis overlaps the latter stages of mitosis. ```
27
G2 of interphase
Chromosomes have been duplicated but aren’t condensed. Two centrosomes have formed that will organize the mitotic spindle.
28
The mitotic spindle is
``` a structure made of microtubules that controls chromosome movement during mitosis. ```
29
An aster
(a radial array of short microtubules) extends from each centrosome in the spindle
30
Prophase:
Chromatin is condensed into discrete duplicated chromosomes that appear as pairs of identical sister chromatids joined at their centromeres.
31
Prometaphase:
Nuclear envelope fragments. Each of the two sister chromatids of each duplicated chromosome has a kinetichore protein to which the microtubules of the spindle attach.
32
Metaphase
The chromosomes are aligned at the metaphase plate, a plane equal distance from the two centrosomes.
33
Anaphase
Sister chromatids of each pair separate and move towards opposite centrosomes. The cell elongates as the microtubules not attached to kinetichores lengthen
34
Telephase
Two daughter nuclei form in the cell. The chromosomes become less condensed. Spindle microtubules are depolymerized.
35
cleavage
In animal cells, cytokinesis occurs by a process | known as cleavage, forming a cleavage furrow
36
In plant cells, a cell plate
forms during cytokinesis
37
binary fission.
Prokaryotes (bacteria and archaea) reproduce by | a type of cell division called binary fission
38
In binary fission, the chromosome replicates | (beginning at an origin of replication),
and the two daughter chromosomes actively move apart. The plasma membrane pinches inward, dividing the cell into two
39
Regulation of the Cell Cycle
``` The frequency of cell division varies with the type of cell. These differences result from regulation at the molecular level. Cancer cells manage to escape the usual controls on the cell cycle. ```
40
cell cycle control system
The sequential events of the cell cycle are directed by a distinct cell cycle control system, which is similar to a clock. The cell cycle control system is regulated by both internal and external controls. The clock has specific checkpoints where the cell cycle stops until a go-ahead signal is received
41
Regulation of the Cell Cycle For many cells, the G1 checkpoint seems to be the most important.
If a cell receives a go-ahead signal at the G1 checkpoint, it will usually complete the S, G2 , and M phases and divide
42
G0 phase.
If the cell does not receive the go-ahead signal, it will exit the cycle, switching into a nondividing state called the G0 phase
43
An example of an internal signal is that kinetochores not attached to spindle microtubules send a molecular signal that delays anaphase
External signals include growth factors, proteins | released by cells that stimulate other cells to divide
44
Cancer cells do not respond normally to the body’s | control mechanisms
Cancer cells may not need growth factors to grow and divide, rather they . – may make their own growth factor – may convey a growth factor’s signal without the presence of the growth factor – may have abnormal cell cycle control