Sleep Disorders ENT Flashcards

1
Q

Overview of sleep disorders?

A

 Approximately one in seven North Americans have a chronic sleep/wake disorder.

 Excessive daytime sleepiness afflicts up to 5% of western society.

 Over half of severely hyper-somnolent patients report loss of job, or disruption of family life.

 Excessive daytime sleepiness has been associated with an increased rate of automobile accidents.

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2
Q

What is OSA?

A

 Cessation of airflow with ongoing respiratory effort.

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3
Q

Symptoms of OSA?

A

Daytime hyper-somnolence: Impaired work performance, Decreased quality of life, Increased rate of automobile accidents

 Hypertension

 Snoring: Witnessed apneic episodes, Choking or gasping episodes

 Other symptoms: Nocturnal headaches, enuresis, gastroesophageal reflux, impotence, respiratory failure, and psychiatric disorders

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4
Q

Assessment of OSA?

A

 History

 Questionnaires: Snoring, Witnessed apneic episodes, Daytime hyper-somnolence, Nocturnal choking

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5
Q

Physical exam of OSA?

A

 Alertness

 BMI

 Neck circumference

 Blood pressure

 Enlarged or crowded oral structures

 Nasal passages

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6
Q

Consequences of OSA?

A

 Subjective complaints: snoring, sleepiness

 Neuropsychological sequelae

 Metabolic Derangements

Hypertension

 Heart and Vascular Disease

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7
Q

Neurobehavioral effects of OSA?

A

 Sizable effect of OSA on the ability to sustain attention over time, particularly on the quality of the performance rather than simple reaction time

 Moderate to severe OSA negatively impacts memory and executive performance—although presence and degree of deficit in these categories is controversial

 QOL studies indicate that pts with OSA have significantly impaired QOL and social functioning and a high prevalence of minor psychiatric morbidity

 Improvements in both subjective and objective tests of sleepiness are seen with CPAP therapy for OSA. These improvements are moderate to large. Subjective scores improve to a larger degree than objective scores.

 Evaluation of attention-based cognitive outcomes, there is a much more modest improvement of functioning with CPAP

 QOL: the large impairments in sleepiness and energy related QOL scores show substantial improvement with CPAP—those with the most severe OSA reap the most benefit

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8
Q

Metabolic effects of OSA?

A

 Insulin Resistance: hyperglycemia resulting from both an impaired insulin secretory response to glucose and decreased insulin effectiveness in stimulating glucose uptake by skeletal muscle and in restraining hepatic glucose production

 Metabolic Syndrome: hyperinsulinemia, glucose intolerance, dyslipidemia, central obesity and hypertension; all risk factors for vascular disease

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9
Q

Diagnosis of OSA?

A

A polysomnogram measures the following parameters during sleep:

 EEG

 EOG

 Leg movement

 EKG

 EMG

 Oxygen saturation

 Airflow

 Chest movement

 Abdomen movement

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10
Q

 Polysomnogram interpretation for OSA?

A

 Sleep staging

 RDI/AHI

 Oxygen Saturation

 Central vs. obstructive apnea

 Mild, moderate, severe apnea

 Periodic leg movements

 Other sleep related difficulties

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11
Q

Treatment options for OSA?

A

 Weight loss

 Avoidance of alcohol

 Smoking cessation

 Alteration of body position during sleep

 Treatment of nasal obstruction

 CPAP

 Oral appliances

 Surgery

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12
Q

Explain the CPAP for OSA?

A

 Positive pressure maintains airway patency

 Titration

 100% effective

 Patients often not compliant.

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13
Q

Oral appliances for OSA?

A

 Oral appliances

 Mandibular repositioning devices

 Fit by a dentist

 Hold the jaw and tongue forward

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14
Q

what do we do for pediatric OSA?

A

 Tonsillectomy and Adenoidectomy is 97% curative in the pediatric population.

 Tonsillectomy for OSA has become the most common reason to perform a tonsillectomy.

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15
Q

Standardization of of tonsil size?

A
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16
Q

History of Tonsilectomy?

A

 In U.S.

 1959: 1.4 million tonsillectomies performed

 1979: 500,000

 1985: 340,000

 1996: 287,000

 In 1950s and 1960s chronic infection primary surgical indication

 Now, airway obstruction and obstructive sleep apnea more common indications

 Improvement in medical management with Abx

17
Q

Complications of Tonsilectomy?

A

 2% post-operative hemorrhage: Most common 5-10 days after surgery

 Dehydration

 POPE—Post-obstructive pulmonary edema.

 Velopharyngeal insufficiency.

18
Q

Adult treatment options for OSA?

A

Surgical options are many, but uvulopalatopharyngoplasty (UP3) has been most commonly employed in adults

19
Q

what is a Uvulectomy?

A

A patient with a large uvula who snores and has few or no symptoms of apnea may benefit from uvulectomy. The patient can be given local anesthesia, and uvulectomy can be performed as an office procedure by using cautery or a carbon dioxide laser. In 1993, laser-assisted uvulopalatoplasty was first described as a procedure for individuals who snore and have mild OSA. The procedure consists of incising the inferior rim of the soft palate and uvula. The tonsils are not removed.

20
Q

Explain nasal reconstruction?

A

Relief of nasal obstruction alone rarely cures OSA; however, patient tolerance and response to nasal CPAP are often improved. Septoplasty, septorhinoplasty, and turbinate reduction may be indicated in patients who have predisposing anatomy. Turbinates can be reduced in a number of different ways, including traditional total or partial turbinectomies, submucous resection, cryotherapy, laser vaporization, bipolar radiofrequency coblation, and radiofrequency ablation.

21
Q

Explain a permanent tracheotomy for OSA?

A

 cures OSA

 indicated most often for severe apnea associated with life-threatening cardiac arrhythmias.

 less frequent indications:

 morbid obesity

 obstruction with severe hypoxia

 disabling daytime somnolence

 Not commonly used today.

22
Q

in a multidisiplinatarian approach to OSA who should be consulted?

A

 ENT

 Neurology (Sleep)

 Pulmonary (Sleep)

 Oral Surgeon

 Sleep Lab

23
Q

Explain UP3?

A

 UP3  Success rate=40% (20%-90%)

 Is it a valued procedure?  Isolated  Combined with other procedures

UP3 cannot be the only treatment for obstruction  Nasal  Palatal  Tongue base

24
Q

is severity of disease an indicator of successful UP3?

A

Severity of disease is NOT a prognostic indicator of successful UP3.

 AHI (5-15)=40% success rate

25
Q

Full options to treat OSA?

A

 CPAP  Oral appliance  Nasal  Nasal Valve  UP2 (radiofrequency)  UP2 (pillar)  UP2 (surgical)
 UP3  TBRF  Genioglossus advancement  Thyro-hyoid suspension  Maxillo-mandibular advancement (MMA)

26
Q

UP3 failure rate?

A

 60% failure rate with UP3  Unchanged  Many actually worse

27
Q

Surgical treatment for OSA?

A

 Surgical treatment

 Strive to avoid failure

 Multiphase treatment should be identified

28
Q

Mild disease requires what sort of resection?

A

UP3 failures  Conservative resections for mild disease

29
Q

BMI grading for OSA?

A

 Grade 0 (<20kg/m2)

 Grade I (20-25 kg/m2)

 Grade II (25-30 kg/m2)

 Grade III (20-35 kg/m2)

 Grade IV (>40 kg/m2)