Sleep Flashcards

1
Q

Which gender is more likely to develop insomnia?

A

Females

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2
Q

Prevalence of chronic insomnia

A

10%

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3
Q

Medical conditions that can cause, contribute, or exacerbate insomnia

A
psychiatric conditions
pain
thyroid abnormalities
asthma
reflux
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4
Q

Medications that can cause, contribute, or exacerbate insomnia

A

SSRIs
Steroids
Stimulants
Beta-agonists

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5
Q

Characteristics of Insomnia

A

Difficulty falling asleep
Frequent nocturnal awakenings
early-morning awakenings
may result in daytime impairments in concentration and school or work performance

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6
Q

Transient insomnia

A

lasts only a few days

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7
Q

Short-term insomnia

A

lasts less than 3 weeks

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8
Q

Chronic insomnia

A

lasts longer than 1 month

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9
Q

How to improve sleep hygiene

A

keep a regular sleep schedule
exercise frequently, but not less than 2 hours before bed
Avoid alcohol and stimulants in the late afternoon and evening
Maintain a comfortable sleeping environment that is dark, quiet, and free of intrusions
Avoid consuming large quantities of food or liquids immediately before bedtime

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10
Q

1st line treatment for insomnia

A

BDZs

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11
Q

BDZ adverse effects

A

residual sedation in waking hours
grogginess
psychomotor impairment

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12
Q

antidepressants used in insomnia treatment

A
trazodone
amitriptyline
mirtazapine
nefaxadone
doxepin
Appealing because it can treat underlying depression as well (2 birds 1 stone)
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13
Q

Why are antidepressants unappealing in treating insomnia?

A

side effects!! (carry over sedation, grogginess, anticholinergic effects (drys up) and weight gain)

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14
Q

Ramelteon Mechanism

A

melatonin receptor agonist

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15
Q

Ramelteon adverse effects

A

fatigue, nausea, dizziness, drowsiness (wanted)

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16
Q

Lunesta (Eszopiclone)

A

DOA - 8 hours
Dose range - 2-3mg
Can be used for up to 6 months to treat chronic insomnia

17
Q

Temazepam

A

DOA - 7 hours
Dose range - 7.5-30mg
moderate duration, well tolerated, and inexpensive

18
Q

Sonata (Zaleplon)

A

DOA - 6 hours
Dose range - 5-10mg
Short-acting, only for difficulty falling asleep

19
Q

Zolpidem

A

DOA - 6-8 hours
Dose range - 5-10mg
Short to moderate duration, with no effects on sleep arcitecture