SLE Flashcards
Give some triggers for SLE.
Smoking
UV radiation
Procainamide, isoniazid and hydralazine
Sex hormone exposure
Three skin features.
Why might they have a sore mouth?
Malar rash
Discoid rash
Photosensitivity
Ulcers in mouth and nose.
Two cardiovascular symptoms.
Libman sacks endocarditis (mitral valve affected)
Myocarditis
What advice would you often a pregnant women with SLE?
Beware of repeated miscarriage especially if it flares up during pregnancy.
What race is most likely to be affected by SLE?
Afro Caribbean> South Asians > Caucasians
What is lupus profundus?
Panniculitis - subcutaneous tissue inflammation
Treatment?
Severe cases?
Lifestyle modification
DMARDs - hydroxychloroquine, azathiprine, mycophenolate
Use of steroids - prednisolone, methylprednisolone
IV cyclophosphamide